Protein Purification
MilliporeSigma™ Calbiochem™ P2Y Antagonist II, BPTU
A phenoxypyridinyl-phenylurea that acts as a highly selective P2Y1 antagonist (Ki = 6nM against 0.5nM 2-MeS-ADP for hu
MilliporeSigma™ Calbiochem™ Ibotenic Acid
A highly potent agonist of NMDA and mGlu receptors.
MilliporeSigma™ Calbiochem™ MLKL Inhibitor, Necrosulfonamide
MLKL Inhibitor, Necrosulfonamide, CAS 432531-71-0, is a cell-permeable inhibitor that covalently modifies Cys88 and blocks human MLKL adaptor function.
MilliporeSigma™ Calbiochem™ GPR40 Agonist II
The GPR40 Agonist II controls the biological activity of GPR40. This small molecule/inhibitor is primarily used for Biochemicals applications.
MilliporeSigma™ Calbiochem™ D-erythro-Sphingosine, N,N-Dimethyl-
A cell-permeable and reversible inhibitor of protein kinase C (PKC; IC50 = 12 μM) and stimulates Src kinase activity.
MilliporeSigma™ Calbiochem™ RSK Inhibitor II
The RSK Inhibitor II, also referenced under CAS 501437-28-1, controls the biological activity of RSK. This small molecule/inhibitor is primarily used for Cell Signaling applications.
MilliporeSigma™ Calbiochem™ Dantrolene, Sodium Salt
A cell-permeable blocker of intracellular calcium release from the sarcoplasmic reticulum that acts by binding to the ryanodine receptor.
MilliporeSigma™ Calbiochem™ Akt Inhibitor V, Triciribine
The Akt Inhibitor V, Triciribine, also referenced under CAS 35943-35-2, controls the biological activity of Akt.
MilliporeSigma™ Calbiochem™ RHC-80267
Selective inhibitor of DAG lipase activity in canine platelets (IC50 = 4 nM) and in a variety of mammalian cells.
MilliporeSigma™ Calbiochem™ Nedd4/Rsp5 Signaling Inducer, NAB2
A cell-permeable compound that protects against alpha-synuclein toxicity.
MilliporeSigma™ Calbiochem™ Okadaic Acid, Potassium Salt
Water-soluble analog of Okadaic Acid. Inhibits protein phosphatases 1 and 2A.
MilliporeSigma™ Calbiochem™ TrkB Agonist, 7,8-Dihydroxyflavone
A cell permeable flavone based compound with neurotrophic and neuroprotective properties
MilliporeSigma™ Calbiochem™ gp130 Inhibitor, SC144
Cell-permeable inhibitor of gp130. Binds to gp130 and induces its phosphorylation at Ser782 in ovarian cancer cells. Suppresses constitutive phosphorylation of and nuclear translocation of Stat3.
MilliporeSigma™ Calbiochem™ Tankyrase 1/2 Inhibitor VI, G007-LK
Tankyrase 1/2 Inhibitor VI, G007-LK, CAS 1380672-07-0, is a cell-permeable, potent and highly selective inhibitor of tankyrase (IC50 = 33 and 26nM for TNKS1 and TNKS2, respectively).
MilliporeSigma™ Calbiochem™ Dynamin Inhibitor V, 34-2
The Dynamin Inhibitor V, 34-2 controls the biological activity of Dynamin. This small molecule/inhibitor is primarily used for Membrane applications.