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An inhibitor of NEDD8-activating enzyme; inhibits NEDDylation of UBC12 in a cell-free assay using recombinant human NAE; selectively inhibits NEDDylation over SUMOylation and ubiquitination in A549 cells; inhibits the growth of A549 cells (GI50 = 5.5 µM); inhibits tumor growth in an AGS gastric adenocarcinoma mouse xenograft model at 60 mg/kg
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
An ENPP3 inhibitor (Ki = 53.7 nM); selective for ENPP3 over ENPP1, ENPP2, TNAP, CD73, NTPDase 1, NTPDase 2, and NTPDase 3; inhibits CAII and CAIX (Kis = 74.7 and 20.3 nM, respectively)
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
Silica membrane columns for large scale non-transfection grade plasmid DNA extraction. 250 ug plasmid DNA binding capacity. 6.5 ml bed volume. Fits into most 15ml centrifuge/culture tubes. Requires proper centrifuge and rotor. Less expensive and faster alternative to anion-exchange columns. For DNA used for cell transfection please try our anion exchange columns (1970050) instead.
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CHAPSO3- [(3-Cholamidopropyl) dimethylammonio]-2-hydroxy-1-propanesulfonate] A nondenaturing zwitterionic detergent suitable for use as a solubilizing agent for membrane proteins Ref: MacDonald, R.C., Biochim. Biophys. Acta, 733, 210 (1983) SpecificationsUltra Pure GradeAppearance: SolidMelting Point: 184-186 °C(lit.)
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
5M NaCl 1 ml. For use with the Zymo-Spin™ ChIP Kit for chromatin immunoprecipitation assays. Sold individually for other applications or as part of the Zymo-Spin™ ChIP Kit.
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CD8 alpha enhances the responses of antigen-specific CTL activated through TCR through binding MHC class I favoring lipid raft partitioning of TCR and inducing intracellular signaling CD8 alpha is also found on dendritic cells and rat macrophages but whether CD8 alpha enhances responses of a partner receptor like TCR to activate these cells is not known
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MW 544.4 Da, Purity >98%. Aminonuclease antibiotic agent. Protein biosynthesis inhibitor. Induces cell cycle arrest in G2/M phase and apoptosis. Inhibits transport of proteins into mitochondria. Inhibits translation in vivo.