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A cell-permeable, reversible inhibitor of a mitochondrial glutaminase splice variant, glutaminase C (IC50 = ~2.5 µM), which is commonly found in cancer cells; blocks transformation induced by Rho GTPases and inhibits the proliferation of cancer cell lines without affecting normal cells
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An ATP-competitive inhibitor of JNK1, JNK2, and JNK3 (IC50s = 150, 220, and 70 nM, respectively); effective in vivo in gerbils, mice, and rats via oral, intravenous, or intraperitoneal administration
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A potent, reversible, ATP-competitive, and selective inhibitor of the Src family of protein tyrosine kinases: p56lck (IC50 = 5 nM), p59fynT (IC50 = 6 nM), Hck (IC50 = 20 nM)
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Includes sample test tubes and positive product control test tubes. The Pyrosate kit is developed as an easy-to-use LAL gel-clot test. The assay does not require special training or laboratory supplies. The step-by-step illustrated instructions allow the user to perform assays within minutes. The Pyrosate kit provides rapid results and is especially convenient for research, testing water and dialysate.
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A pyrimidine dicarboxamide that selectively inhibits MMP-13 (IC50 = 8 nM); blocks osterix-dependent calcification of matrices in limb bud cells during endochondral ossification
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Protein. Human FABP1 aa 1-127 is fused at the N-terminus to a His-tag. Source E. coli. Endotoxin content <1EU/µg purified protein LAL test Lonza. Liquid. 0.2µm-filtered solution in 20mM Tris-HCl, pH 8. Purity >90% SDS-PAGE. FABP1 is a fatty acid binding protein in adipocytes. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABPs regulate the fatty acid uptake, transport, and metabolism. FABP1 is required for cholesterol synthesis and metabolism.
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The EasySep™ Human Plasmacytoid DC Enrichment Kit is designed to isolate plasmacytoid dendritic cells (pDC) from fresh peripheral blood mononuclear cells by negative selection. Unwanted cells are targeted for removal with Tetrameric Antibody Complexes recognizing non-pDCs and dextran-coated magnetic particles. The labeled cells are separated using the EasySep™ magnet without the use of columns. Desired cells are poured off into a new tube.
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