Protein Purification
MilliporeSigma™ Calbiochem™ Guanosine 3',5'-cyclic Monophosphorothioate, β-Phenyl-1,N2-etheno-8-bromo-, Rp-Isomer, Sodium Salt
A metabolically-stable, competitive inhibitor of protein kinase G types 1α and 1β (Ki = 30 nM).
MilliporeSigma™ Calbiochem™ InSolution™ Necrostatin-1
A cell-permeable, potent, and selective blocker of necroptosis (EC50 = 494nM in FADD-deficient Jurkat cells treated with TNF-α), a nonapoptotic necrotic cell death pathway mediated by death-domain receptors (DRs) that offers neuroprotection in a murine model of ischemic brain inj
MilliporeSigma™ Calbiochem™ Vacuolin-1
A cell-permeable triazine based compound that inhibits Ca
MilliporeSigma™ Calbiochem™ Acetyl-Pepstatin
An aspartyl protease inhibitor that acts as an effective inhibitor of HIV-1 proteinase (Ki = 20nM at pH 4.7) and HIV-2 proteinase (Ki = 5nM at pH 4.7).
MilliporeSigma™ Calbiochem™ CX546
A positive allosteric modulator selective for the AMPA receptors.
MilliporeSigma™ Calbiochem™ Pancuronium Dibromide
A highly potent competitive antagonist selective for nAChRs (IC50
MilliporeSigma™ Calbiochem™ AMPA Agonist, CMPA
The AMPA Agonist, CMPA controls the biological activity of AMPA. This small molecule/inhibitor is primarily used for Biochemicals applications.
MilliporeSigma™ Calbiochem™ MMP-9 Inhibitor I
MMP-9 Inhibitor I, CAS 1177749-58-4, is a cell-permeable, potent, and reversible MMP-9 Inhibitor (IC50 = 5 nM). At high concentration inhibits MMP-1 (IC50 = 1.05 μM) & MMP-13 (IC50 = 113 nM).
MilliporeSigma™ Calbiochem™ EGFR Activator, NSC 228155
A nitro-benzoxadiazole compound that directly binds to the dimerization domain of sEGF receptor to generate stable dimers and allosterically activate the receptor.
MilliporeSigma™ Calbiochem™ Triptolide, Tripterygium wilfordii
A novel diterpene triepoxide isolated from the Chinese herb Tripterygium wilfordii that acts as a potent immunosuppressant and anti-inflammatory agent.
MilliporeSigma™ Calbiochem™ ER Export Inhibitor II, FLI-06
A cell-permeable compound that reversibly blocks cellular glycosylation and surface expression of Notch, APP, Klotho by blocking events prior to cargo assembly at the ER exit sites.
MilliporeSigma™ Calbiochem™ Caspase-3 Inhibitor I, Cell-Permeable
The Caspase-3 Inhibitor I, Cell-Permeable controls the biological activity of Caspase-3. This small molecule/inhibitor is primarily used for Cancer applications.
MilliporeSigma™ Calbiochem™ GGTI-286
A potent, cell-permeable, and selective inhibitor of GGTase I.
MilliporeSigma™ Calbiochem™ Ubiquitin Isopeptidase Inhibitor I, G5
The Ubiquitin Isopeptidase Inhibitor I, G5, also referenced under CAS 108477-18-5, controls the biological activity of Ubiquitin Isopeptidase. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
MilliporeSigma™ Calbiochem™ SecinH3
A cell-permeable triazolo compound that acts as a Sec7 domain-binding, selective antagonist against cytohesin family small GEFs.