Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ Dynamin Inhibitor II, MiTMAB
The Dynamin Inhibitor II, MiTMAB, also referenced under CAS 1119-97-7, controls the biological activity of Dynamin. This small molecule/inhibitor is primarily used for Membrane applications.
MilliporeSigma™ Calbiochem™ Stauprimide
A cell-permeable ESCs (Embryonic Stem Cells) EMT (Epithelial-Mesenchymal Transition) inducer that is reported to prime/sensitize human and murine ESC cultures for much more enhanced/efficient differentiation into progenitor cells of multiple lineages.
MilliporeSigma™ Calbiochem™ MAGL Inhibitor III, JZL184
The MAGL Inhibitor III, JZL184, also referenced under CAS 1101854-58-3, controls the biological activity of MAGL.
MilliporeSigma™ Calbiochem™ Protease Inhibitor Cocktail Set I
A cocktail of five protease inhibitors that will inhibit a broad range of proteases and esterases. Supplied with a data sheet.
MilliporeSigma™ Calbiochem™ Bax-Inhibiting Peptide, V5
A cell-permeable pentapeptide based on the Ku70-Bax inhibiting domain that offers cytoprotection.
MilliporeSigma™ Calbiochem™ PKCθ Pseudosubstrate Inhibitor, Myristoylated
The PKCθ Pseudosubstrate Inhibitor, Myristoylated controls the biological activity of PKCθ. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ InSolution™ Y-27632 in DMSO
InSolution™ Y-27632 is a 10mm solution in DMSO. A highly potent, cell-permeable, reversible, and selective inhibitor of Rho-associated protein kinases (Ki = 140nM for p160ROCK).
MilliporeSigma™ Calbiochem™ Cisplatin
Reported to sensitize glioma cells to TNF-α-induced apoptosis.
MilliporeSigma™ Calbiochem™ Nitric Oxide Synthase, Neuronal Inhibitor I
The Nitric Oxide Synthase, Neuronal Inhibitor I, also referenced under CAS 357965-99-2, controls the biological activity of neuronal Nitric Oxide Synthase. This small molecule/inhibitor is primarily used for Inflammation/Immunology applications.
MilliporeSigma™ Calbiochem™ CARM1 Inhibitor
The CARM1 Inhibitor controls the biological activity of CARM1. This small molecule/inhibitor is primarily used for Cell Structure applications.
MilliporeSigma™ Calbiochem™ MreB Perturbing Compound A22
A cell-permeable isothiourea compound that specifically, rapidly and reversibly perturbs MreB function without affecting eukaryotic actin polymerization.
MilliporeSigma™ Calbiochem™ 11beta-HSD1 Inhibitor, 10j
The 11beta-HSD1 Inhibitor, 10j, also referenced under CAS 1009373-58-3, controls the biological activity of 11beta-HSD1. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
MilliporeSigma™ Calbiochem™ Autotaxin Inhibitor II, HA130
A thiazolidinedione that is designed to target the ATX active site thr210 with a boronic moiety and shown to potently inhibit ATX lysoPLD activity (IC50 ∽28nM using recombinant human ATX or human plasma) in a reversible manner with a mixed-type Lineweaver-Burk kinet
MilliporeSigma™ Calbiochem™ Bcr-abl Inhibitor IV, Imatinib
A cell-permeable, orally bioavailable 2-phenylaminopyrimidine derived compound that competitively binds to ATP-binding site of Abl and stabilizes the inactive conformation, and acts as a highly potent and reversible inhibitor of Abl (IC50 = 38, 25 and 25nM for v-Abl, Bcr-Abl, and c-Abl, respective
MilliporeSigma™ Calbiochem™ DPDPE
A potent agonist selective for δ opioid receptor (EC50