Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ PICK1 PDZ Domain Inhibitor, FSC231
The PICK1 PDZ Domain Inhibitor, FSC231 controls the biological activity of PICK1. This small molecule/inhibitor is primarily used for Neuroscience applications.
MilliporeSigma™ Calbiochem™ L-(–)-Norepinephrine-(+)-bitartrate
α,β-Adrenergic agonist.
MilliporeSigma™ Calbiochem™ Rolipram
A cell-permeable, selective inhibitor of cAMP-specific phosphodiesterase (PDE IV; IC50 = 800 nM).
MilliporeSigma™ Calbiochem™ Ebselen
A cell-permeable, non-selective inhibitor of COX-1 and COX-2.
MilliporeSigma™ Calbiochem™ AG 490
A cell-permeable, reversible, substrate competitive, and potent inhibitor of epidermal growth factor receptor kinase autophosphorylation (IC50 = 100 nM).
MilliporeSigma™ Calbiochem™ CL316243 Hydrate
A very potent agonist highly selective for β3 adrenoceptors (EC50 =
MilliporeSigma™ Calbiochem™ MIF Antagonist, ISO-1
The MIF Antagonist, ISO-1, also referenced under CAS 478336-92-4, controls the biological activity of MIF.
MilliporeSigma™ Calbiochem™ PARP Inhibitor IX, EB-47
The PARP Inhibitor IX, EB-47 controls the biological activity of PARP. This small molecule/inhibitor is primarily used for Cell Structure applications.
MilliporeSigma™ Calbiochem™ FPT Inhibitor II
The FPT Inhibitor II controls the biological activity of FPT. This small molecule/inhibitor is primarily used for Cancer applications.
MilliporeSigma™ Calbiochem™ RNA Polymerase I Inhibitor II, BMH-21
A cell-permeable compound that blocks the growth and viability of a variety of cancer cell lines (GI50 = 160 nM in NCI-60 cells), but does not affect normal cells.
MilliporeSigma™ Calbiochem™ D609, Potassium Salt
Selective inhibitor of phosphatidylcholine (PC)-specific phospholipase C (Ki = 5-10 μM).
MilliporeSigma™ Calbiochem™ VEGFR2/Flt3/c-Kit Inhibitor
The VEGFR2/Flt3/c-Kit Inhibitor, also referenced under CAS 796967-10-7, controls the biological activity of VEGFR2/Flt3/c-Kit. This small molecule/inhibitor is primarily used for Activators/Inducers applications.
MilliporeSigma™ Calbiochem™ JAK2 Inhibitor X, FLLL32
A cell permeable analog of curcumin that acts as a specific inhibitor of JAK2 (≈5 μM) and blocks STAT3 phosphorylation in MDA-MB-231 and PANC-1 cancer cells.
MilliporeSigma™ Calbiochem™ TMEM16A Activator, Eact
The TMEM16A Activator, Eact modulates the biological activity of TMEM16A. This small molecule/inhibitor is primarily used for Activators/Inducers applications.
MilliporeSigma™ Calbiochem™ Bufalin
A cardiotonic steroid isolated from toads of Bufo species that potently inhibits ouabain-sensitive Na+,K+-ATPase activity (IC50 = 1.4 nM).