Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ NAE Inhibitor, MLN4924
NAE Inhibitor, MLN4924, CAS 951950-33-7, is an AMP mimetic that forms a NAE-catalyzed NEDD8 adduct, which acts as a tight-binding, ATP-competitive NAE inhibitor (IC50 = 4.7nM).
MilliporeSigma™ Calbiochem™ InSolution™ Tamoxifen, 4-Hydroxy-, (Z)-
A 10 mM (2 mg/516 μL) sterile-filtered solution of (Z)-4-Hydroxytamoxifen in ethanol.
MilliporeSigma™ Calbiochem™ Oxymetazoline Hydrochloride
Oxymetazoline Hydrochloride is an α2-Adrenergic receptor agonist. Enhances EGF- and PDGF-induced DNA synthesis.
MilliporeSigma™ Calbiochem™ InSolution™ SU5402
Inhibits the tyrosine kinase activity of FGFR1 (IC50 = 10-20μM in the presence of 1mm ATP) by interacting with the catalytic domain of FGFR1
MilliporeSigma™ Calbiochem™ Tankyrase1/2 Inhibitor, XAV939
The Tankyrase1/2 Inhibitor, XAV939 controls the biological activity of Tankyrase1/2. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ RNA Polymerase III Inhibitor
RNA Polymerase III Inhibitor, CAS 577784-91-9, is a cell-permeable inhibitor of RNA Polymerase III (IC50 = 27 and 32 μM for human and S. cerevisiae RNA Pol III, respectively).
MilliporeSigma™ Calbiochem™ InSolution™ STAT3 Inhibitor VI, S3I-201
The InSolution™ STAT3 Inhibitor VI, S3I-201, also referenced under CAS 501919-59-1, controls the biological activity of STAT3. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ PDGFR Tyrosine Kinase Inhibitor V
The PDGFR Tyrosine Kinase Inhibitor V, also referenced under CAS 347155-76-4, controls the biological activity of PDGFR Tyrosine Kinase. This small molecule/inhibitor is primarily used for Phosphorylation and Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ SU1498
A potent, reversible, ATP-competitive and selective inhibitor of Flk-1 kinase (IC50 = 700 nM), a vascular endothelial growth factor (VEGF) receptor kinase.
MilliporeSigma™ Calbiochem™ InSolution™ Rac1 Inhibitor II, Z62954982
The InSolution™ Rac1 Inhibitor II, Z62954982, also referenced under CAS 1090893-12-1, controls the biological activity of Rac1. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ Ro-31-8425
A potent, cell-permeable, reversible, ATP-competitive, and selective protein kinase C inhibitor (IC50 = 15 nM for rat brain PKC).
MilliporeSigma™ Calbiochem™ SU9516
A cell-permeable 3-substituted indolinone compound that displays anti-proliferative and proapoptotic properties in tumor cells.
MilliporeSigma™ Calbiochem™ Tankyrase 1/2 Inhibitor VI, G007-LK
Tankyrase 1/2 Inhibitor VI, G007-LK, CAS 1380672-07-0, is a cell-permeable, potent and highly selective inhibitor of tankyrase (IC50 = 33 and 26nM for TNKS1 and TNKS2, respectively).
