Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ Caffeine
Trimethylated xanthine that acts as a potent central nervous system stimulant.
MilliporeSigma™ Calbiochem™ Bexarotene
A retinoid X receptor (RXR) agonist that can permeate the blood-brain barrier and rapidly reduce Aβ40 and Aβ42 levels in APP/PS1 mice in an ApoE-dependent manner.
MilliporeSigma™ Calbiochem™ 2,3-Butanedione 2-Monoxime
An inhibitor of skeletal and cardiac muscle contraction.
MilliporeSigma™ Calbiochem™ BMP Inhibitor II, DMH1
The BMP Inhibitor II, DMH1, also referenced under CAS 1206711-16-1, controls the biological activity of BMP. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ InSolution™Blebbistatin, Racemic
InSolution™Blebbistatin, Racemic, is a 50mm in 90% DMSO. A cell-permeable, selective, and reversible inhibitor of nonmuscle myosin II. Blocks cell blebbing and disrupts cell migration and cytoKinesis.
MilliporeSigma™ Calbiochem™ CA-074
CA-074, also referenced under CAS 134448-10-5, modulates the biological activity of cathepsin B. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
MilliporeSigma™ Calbiochem™ Adenosine 3',5'-cyclic Monophosphate, 8-Bromo-, Sodium Salt
Cell-permeable cAMP analog that has greater resistance to phosphodiesterases than cAMP.
MilliporeSigma™ Calbiochem™ bpV(HOpic)
A potent phosphotyrosine phosphatase inhibitor.
MilliporeSigma™ Calbiochem™ (+)-Brefeldin A, Eupenicillium brefeldianum
Specifically and reversibly blocks translocation of proteins from the endoplasmic reticulum (ER) to the Golgi apparatus without affecting endocytosis or lysosome function.
MilliporeSigma™ Calbiochem™ (±)-Blebbistatin
(±)-Blebbistatin, CAS 674289-55-5, is a cell-permeable, selective, and reversible inhibitor of nonmuscle myosin II. Blocks cell blebbing and disrupts cell migration & cytoKinesis in vertebrate cells.
MilliporeSigma™ Calbiochem™ CA-074 Me
CA-074 Me, CAS 147859-80-1, is a cell-permeable analog of CA-074 that acts as an irreversible inhibitor of intracellular cathepsin B.
MilliporeSigma™ Calbiochem™ Calyculin A, Discodermia calyx
Calyculin A, CAS 101932-71-2, is a cell-permeable inhibitor of protein phosphatase 2A (IC50 = 0.5-1 nM) and protein phosphatase 1 (PP1; IC50 = 2 nM).
MilliporeSigma™ Calbiochem™ Camptothecin, Camptotheca acuminata
A cell-permeable DNA topoisomerase I inhibitor.
MilliporeSigma™ Calbiochem™ Pre-mRNA Splicing Inhibitor, Isoginkgetin
The Pre-mRNA Splicing Inhibitor, Isoginkgetin, also referenced under CAS 548-19-6, blocks the spliceosome-meidated splicing process.
MilliporeSigma™ Calbiochem™ IκB Kinase Inhibitor Peptide, Cell-Permeable
The IκB Kinase Inhibitor Peptide, Cell-Permeable controls the biological activity of IκB Kinase. This small molecule/inhibitor is primarily used for Inflammation/Immunology applications.