Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ Caspase-1 Substrate VI, Fluorogenic
Fluorogenic caspase-1 substrate.
MilliporeSigma™ Calbiochem™ InSolution™ SB 202190
A potent and cell-permeable inhibitor of p38 MAP kinase
MilliporeSigma™ Calbiochem™ Zinc (II) Protoporphyrin IX
A potent and selective inhibitor of heme oxygenase, the enzyme which generates carbon monoxide (CO) and biliverdin.
MilliporeSigma™ Calbiochem™ Etomoxir
A cell-permeable, irreversible, and stereospecific compound that is shown to inhibit carnitine palmitoyltransferase (CPT)-1 and DGAT activity in the mitochondria of rat heart H9c2 myoblastic cells.
MilliporeSigma™ Calbiochem™ PI3Kδ Inhibitor, SW30
The PI3Kδ Inhibitor, SW30 controls the biological activity of PI3Kδ. This small molecule/inhibitor is primarily used for Membrane applications.
MilliporeSigma™ Calbiochem™ 4-Hydroxyphenylretinamide
A synthetic amide of all-trans retinoic acid (RA) that displays reduced toxicity relative to RA while maintaining significant biological activity.
MilliporeSigma™ Calbiochem™ Phosphoramidon, Disodium Salt
Inhibits some metalloendopeptidases.
MilliporeSigma™ Calbiochem™ MK-886
A cell-permeable, orally active NSAID that blocks cellular Cox pathway PGE2 production by inhibiting COX-1 and mPGES-1, but not COX-2, activity, as well as suppresses cellular 5-LO pathway activation by inhibiting FLAP, rather than 5-LO, activity.
MilliporeSigma™ Calbiochem™ sFRP-1 Inhibitor
The sFRP-1 Inhibitor, also referenced under CAS 915754-88-0, controls the biological activity of sFRP-1. This small molecule/inhibitor is primarily used for Activators/Inducers applications.
MilliporeSigma™ Calbiochem™ SecinH3
A cell-permeable triazolo compound that acts as a Sec7 domain-binding, selective antagonist against cytohesin family small GEFs.
MilliporeSigma™ Calbiochem™ Elastase Substrate IV, Colorimetric
A specific substrate for pancreatic elastase.
MilliporeSigma™ Calbiochem™ Autocamtide-2 Related Inhibitory Peptide II, Cell-permeable
The Autocamtide-2 Related Inhibitory Peptide II, Cell-permeable controls the biological activity of calmodulin-dependent protein kinase II. This small molecule/inhibitor is primarily used for Phosphorylation and Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ Hh Signaling Antagonist X, Itraconazole
The Hh Signaling Antagonist X, Itraconazole, also referenced under CAS 84625-61-6, controls the biological activity of Hh pathway. This small molecule/inhibitor is primarily used for Cell Signaling applications.
MilliporeSigma™ Calbiochem™ Valproic Acid, Sodium Salt
A cell-permeable, short-chained fatty acid that inhibits histone deacetylase (IC50 = 400 μM for HDAC1).
MilliporeSigma™ Calbiochem™ G-Protein βγ Binding Peptide, mSIRK
A cell-permeable, N-myristoylated G-protein βγ selective binding peptide that disrupts the interaction between α and βγ subunits and promotes the α subunit dissociation without stimulating nucleotide exchange.