Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ Akt Activator II, SC79
Akt Activator II, SC79, CAS 305834-79-1, is a cell-permeable compound that interacts with Akt PH domain PIP3 binding pocket and makes it more susceptible to phosphorylation by upstream Kinases.
MilliporeSigma™ Calbiochem™ (-)-Blebbistatin
The active enantiomer of (±)-Blebbistatin that accounts for the inhibitory activity towards ATPase and myosin II-dependent cellular processes.
MilliporeSigma™ Calbiochem™ TrkB Antagonist, ANA-12
A cell-permeable thiophene carboxymide derived compound that acts as a direct and selective antagonist of TrkB receptor
MilliporeSigma™ Calbiochem™ InSolution™Blebbistatin, Racemic
InSolution™Blebbistatin, Racemic, is a 50mm in 90% DMSO. A cell-permeable, selective, and reversible inhibitor of nonmuscle myosin II. Blocks cell blebbing and disrupts cell migration and cytoKinesis.
MilliporeSigma™ Calbiochem™ InSolution™ ALLN
A 10mm (5mg/1.30 ml) solution of ALLN (Cat. No. 208719) in DMSO.
MilliporeSigma™ Calbiochem™ Bryostatin 1
A macrocyclic lactone with antitumor properties.
MilliporeSigma™ Calbiochem™ (+)-Brefeldin A, Eupenicillium brefeldianum
Specifically and reversibly blocks translocation of proteins from the endoplasmic reticulum (ER) to the Golgi apparatus without affecting endocytosis or lysosome function.
MilliporeSigma™ Calbiochem™ BX-795
BX-795, also referenced under CAS 702675-74-9, modulates the biological activity of multiple kinases. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ BMP Inhibitor II, DMH1
The BMP Inhibitor II, DMH1, also referenced under CAS 1206711-16-1, controls the biological activity of BMP. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ Dantrolene, Sodium Salt
A cell-permeable blocker of intracellular calcium release from the sarcoplasmic reticulum that acts by binding to the ryanodine receptor.
MilliporeSigma™ Calbiochem™ Deltamethrin
Synthetic type II pyrethroid. Potent inhibitor of calcineurin. Causes an increase in neurotransmitter release at synapses, and increases intrasynaptosomal Ca2+ levels.
MilliporeSigma™ Calbiochem™ 1-β-D-Arabinofuranosylcytosine
Anticancer, antiviral agent that is especially effective against leukemias.
MilliporeSigma™ Calbiochem™ Cytoplasmic Dynein Inhibitor, Ciliobrevin D
Ciliobrevin D is a cell-permeable, reversible, and specific blocker of AAA+ ATPase motor cytoplasmic dynein. Disrupts spindle pole focusing and kinetochore-microtubule attachment (≈10 to 40 μM).
MilliporeSigma™ Calbiochem™ Daidzein
Inactive analog of Genistein.
MilliporeSigma™ Calbiochem™ Cytochalasin D, Zygosporium mansonii
Cytochalasin D, Zygosporium mansonii, CAS 22144-77-0, is a fungal toxin that is about 10-fold more potent than cytochalasin B in inhibiting actin filament function. Blocks cytoplasmic division.