Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ Beclin-1 Activator I, TAT-Beclin-1, Scrambled
A randomly shuffled Beclin-1 (267-284) peptide made cell-permeable by covalently attaching to HIV-1 Tat protein transduction domain via a diglycine linker
MilliporeSigma™ Calbiochem™ ADP-HPD, Dihydrate, Ammonium Salt
ADP-HPD, Dihydrate is an amino analog of ADP-ribose that acts as a highly potent, noncompetitive, and specific inhibitor of poly(ADP-ribose) glycohydrolase (PARG; IC50 = 120 nM).
MilliporeSigma™ Calbiochem™ InSolution™ Epoxomicin, Synthetic
InSolution™ Epoxomicin, Synthetic, is a 1 mM solution of Epoxomicin, Synthetic (Cat. No. 324800) in DMSO.
MilliporeSigma™ Calbiochem™ Alsterpaullone
A cell-permeable, potent, reversible, and ATP competitive inhibitor of GSK-3β (IC50 = 4 nM) and Cdk1/cyclin B (IC50 = 35 nM).
MilliporeSigma™ Calbiochem™ Kifunensine, Kitasatosporia kifunense
A potent alkaloid inhibitor of mannosidase I.
MilliporeSigma™ Calbiochem™ Apoptosis Activator VI, CD437/AHPN
The Apoptosis Activator VI, CD437/AHPN, also referenced under CAS 125316-60-1, modulates Apoptosis. This small molecule/inhibitor is primarily used for Cancer applications.
MilliporeSigma™ Calbiochem™ InSolution™ Akt Inhibitor VIII, Isozyme-Selective, Akti-1/2
The InSolution™ Akt Inhibitor VIII, Isozyme-Selective, Akti-1/2 controls the biological activity of Akt.
MilliporeSigma™ Calbiochem™ InSolution™ SRT1720, HCl
A 25 mM (10 mg/650 μl) sterile-filtered solution of SRT1720, HCl in DMSO.
MilliporeSigma™ Calbiochem™ MMP-2 Inhibitor IV
The MMP-2 Inhibitor IV controls the biological activity of MMP-2. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
MilliporeSigma™ Calbiochem™ U0126
U0126, CAS 109511-58-2, is a potent and specific inhibitor of MEK1 (IC50 = 72 nM) and MEK2 (IC50 = 58 nM). The inhibition is noncompetitive with respect to both ATP and ERK.
MilliporeSigma™ Calbiochem™ HIF-1α Translation Inhibitor, KC7F2
The HIF-1α Translation Inhibitor, KC7F2, also referenced under CAS 927822-86-4, controls the biological activity of HIF-1α. This small molecule/inhibitor is primarily used for Cell Structure applications.
MilliporeSigma™ Calbiochem™ Exo1
A cell-permeable methylanthranilate analog that reversibly inhibits vesicular traffic from ER to Golgi in mammalian cells by inducing tubulation and collapsing of the Golgi membrane.
MilliporeSigma™ Calbiochem™ Leupeptin, Hemisulfate, Microbial
Leupeptin hemisulfate, CAS 103476-89-7, is a reversible inhibitor of trypsin-like proteases and cysteine proteases.
MilliporeSigma™ Calbiochem™ AG 126
A cell-permeable inhibitor of lipopolysaccharide (LPS)-induced synthesis of tumor necrosis factor-α and nitric oxide in murine peritoneal macrophages.
MilliporeSigma™ Calbiochem™ Pamidronate, Disodium Salt
A potent and specific inhibitor of bone resorption that does not cause any significant detrimental effect on bone growth and mineralization at concentrations used.