Cell Line Lysates
Cayman Chemical Mutnt IDH1-IN-1 5mg
An inhibitor of mutant IDH1 (IC50s = 42, 4, and 80 nM for IDH1R132H/R132H, IDH1R132C/R132C, and IDH1R132H/WT, respectively, for conversion of α-KG to 2-HG); selective for IDH1 mutant conversion of α-KG to 2-HT over IDH1WT/WT conversion of isocitrate to α-KG (IC50 = 1,998 nM) and over IDH2 (IC50s = >10,000 nM); inhibits 2-HG production in vitro (IC50 = 81.5 nM)
Cayman Chemical HerbImycIn C 2.5mg
A bacterial metabolite; cytotoxic to HeLa and Ehrlich cells (IC50s = 7.3 and 1.2 μg/ml, respectively)
Abcam Human EI24 knockout HeLa cell lysate.
Human EI24 knockout HeLa cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human THEMIS2 (ICB1) knockout A549 cell lysate.
Human THEMIS2 (ICB1) knockout A549 cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
ABclonal Technology Phospho-MYL9-T18/S19 Rabbit pAb
Myosin, a structural component of muscle, consists of two heavy chains and four light chains. The protein encoded by this gene is a myosin light chain that may regulate muscle contraction by modulating the ATPase activity of myosin heads. The encoded protein binds calcium and is activated by myosin light chain kinase. Two transcript variants encoding different isoforms have been found for this gene.
Abcam Human CERK knockout HEK-293T cell lysate.
Human CERK knockout HEK-293T cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human USP42 knockout HeLa cell lysate.
Human USP42 knockout HeLa cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human RBBP7 (RbAp46) knockout HCT116 cell lysate.
Human RBBP7 (RbAp46) knockout HCT116 cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Cayman Chemical DeacetylravIdomycIn 2.5mg
A microbial metabolite with light-dependent antibiotic and anticancer activities; active against Gram-positive bacteria including B. subtilis, S. aureus, S. epidermidis, and E. faecalis (MICs = 0.78-1.56 and <0.006-0.049 μg/ml in the absence and presence of fluorescent light, respectively); reduces colony formation by human colon cancer cells in a clonogenic assay in a light-dependent manner
World Precision Instrument Liquid Waveguide Capillary Cell, 500 cm pathlength
UV/VIS/NIR absorbance spectroscopy is governed by Beer’s Law, where the absorbance signal is proportional to chemical concentration, light path length and the compound’s specific molar absorption coefficient. Typical optical pathlengths of cuvettes and flow cells are between 0.2cm and 10 cm. Longer pathlengths are difficult to achieve due to mechanical constraints. Liquid Waveguide Capillary Cells (LWCCs) fill this gap. LWCCs are fiber optic flow cells that combine an increased optical pathlength (10–500 cm) with small sample volumes ranging from 2.4 µL to about 3mL. Compared with a standard 1cm cell, a 1 mAU signal is enhanced one hundred fold with a 100 cm flowcell to 100 mAU, using WPI’s patented aqueous waveguide technology.*
They can be connected via optical fibers to a spectrophotometer with fiber optic capabilities.
Abcam Human VAC14 knockout HeLa cell lysate.
Human VAC14 knockout HeLa cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Cayman Chemical AmIdepsIn A 2.5mg
A fungal metabolite that inhibits DGAT activity, preventing triacylglycerol formation (IC50s = 10.2 and 15.5 µM in rat liver microsomes and Raji cells, respectively
Abcam Human IFI16 knockout A549 cell lysate.
Human IFI16 knockout A549 cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human TRAPPC2L knockout HEK-293T cell lysate.
Human TRAPPC2L knockout HEK-293T cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human RPS27L knockout HeLa cell lysate.
Human RPS27L knockout HeLa cell lysate.
The product is subject to the following: Abcam Restricted Use Statement