Tissue Lysates
Cayman Chemical SynthetIc AlysIn 1mg
An isothiocyanate with diverse biological activities; active against a variety of bacteria; directly inhibits PAH-induced CYP1A1 and CYP1A2 activity in MCF-7 cells at 0.5-2.5 µM; inhibits proliferation of HCT116 colon cancer cells (IC50 = 50s = 168 and 20 µM, respectively)
Cayman Chemical SynthetIc XAV939 1mg
A small molecule inhibitor of tankyrase 1 and 2 (IC50 = 11 and 4 nM, respectively); increases the protein levels of the axin-GSK3β complex and promotes the degradation of β-catenin; inhibits colony formation of APC-deficient colorectal cancer cells at 0.33 µM
Cayman Chemical GLP-11-32bulfrogtrIf 1mg
An endogenous incretin hormone; increases intracellular cAMP levels using HEK293 cells expressing human GLP-1R (EC50 = 0.051 nM); reduces blood glucose levels in an OGTT in fasted mice at 30 mg/kg
Cayman Chemical SynthetIc FumagIlol 1mg
A sesquiterpenoid with diverse biological activities; inhibits METAP2 (IC50 = 230 nM for the human enzyme); active against G. lamblia (IC50 = 3.4 µM); reduces the proliferation of isolated calf pulmonary artery endothelial cells (IC50 = 8.09 µM) and HUVECs (EC50 = 49 nM); inhibits the proliferation of isolated mouse splenocytes in a mixed lymphocyte reaction (IC50 = 250 nM)
Cayman Chemical BeauverIolIde I 1mg
A cyclodepsipeptide inhibitor of lipid droplet formation; inhibits lipid droplet formation at 3 and 10 µM and inhibits cholesterol synthesis (IC50 = 0.78 µM) in primary mouse peritoneal macrophages; inhibits ACAT activity in mouse macrophage membranes (IC50 = 6 µM)
Cayman Chemical GLP-17-36 amIdetrIfluoro 1mg
A peptide hormone released from intestinal L-cells upon nutrient consumption that binds the GLP-1 receptor (pIC50 = 8.5) in the pancreas and displays various antidiabetic effects
Cayman Chemical SynthetIc Bergaptol 1mg
A furanocoumarin with diverse biological activities; inhibits CYP3A4 (IC50 = 24.92 µM); scavenges DPPH and ABTS radicals in cell-free assays (EC50s = 26.66 and 13.55 UG/ml, respectively); reduces the replication of L. donovani, T. b. brucei, and T. cruzi in L6 myoblasts (IC50s = 2.5, 22.1, and 68 UG/ml, respectively); induces cell cycle arrest in the S phase and apoptosis in MCF-7 cells in a concentration-dependent manner; decreases the proliferation of HeLa and HepG2 cells (IC50s = 58.57 and 68.42 µM, respectively)
Cayman Chemical SynthetIc NImbIn 1mg
A limonoid with diverse biological activities; inhibits the growth of D. oryzae by 64.8% at 1,000 ppm; has antifeedant activity against S. littoralis in a choice test at 0.02-2,000 μM; decreases melanin content to 20.9% of control in B16 murine melanoma cells at 25 μg/ml; inhibits TPA-induced activation of EBV-EA in Raji cells (IC50 = 499 mol ratio/32 pmol TPA)
Cell Sciences Inc Research Grade Alnuctamab, Trivalent Bispecific Monoclonal Antibody, 1.0 mg
Research Grade Alnuctamab is a trivalent, bispecific humanized monoclonal antibody designed for laboratory research applications. It uniquely targets human BCMA and CD3e, facilitating T-cell-mediated targeting, making it an advanced reagent for enhanced research results. Provided in a quantity of 1.0 mg, it ensures optimal performance across various research protocols, delivering stability for up to 1 year.
Cayman Chemical UnIdentIfIed AcremIn I 1mg
A fungal metabolite; inhibits germination of P. viticola sporangia by 23.2 and 32.8% at 0.5 and 1 mM, respectively
Cayman Chemical SynthetIc ScoulerIn 1mg
A benzylisoquinoline alkaloid with diverse biological activities; selectively binds to the dopamine D1 and D2 receptors (Kis = 22 and 214 nM, respectively) over 5-HT1A and 5-HT2A receptor subtypes in HEK293 cells at 10 µM; inhibits proliferation in a panel of leukemia cell lines (IC50s = 2.7-6.5 µM); inhibits methamphetamine-induced conditioned place preference in mice at 5 mg/kg
Cayman Chemical CardIolIpIn18 018 018 01 1mg
A phospholipid containing the long-chain saturated fatty acid stearic acid
Cayman Chemical 5-trns ProstaglndIn E2 1mg
5-trans PGE2 occurs naturally in some gorgonian corals and is a common impurity in commercial lots of PGE1.{2213} It is 18 times more potent than PGE2 in activating adenylate cyclase in NCB-20 cell homogenates.{2180} 5-trans PGE2 accelerates fibrinolysis by enhancing plasminogen activation mediated by tissue-type plasminogen activator.{2177} It also inhibits platelet aggregation in human PRP with an IC50 of 180 nM.{1607}