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MCC-AAQ-Exa is a drug-linker conjugate used in the development of antibody-drug conjugates (ADCs). It is produced by condensing an MCC maleimide-containing linker with an exatecan payload and is supplied as a research reagent for conjugation workflows.
Drug-linker conjugate for antibody-drug conjugate (ADC) development.
Contains an MCC maleimide linker enabling thiol conjugation to antibodies.
Derived from exatecan payload for potent cytotoxic activity once internalized.
Molecular weight 924.97.
Chemical formula C47H53FN8O11.
Purity 95.3% (as supplied).
CAS number 3052836-65-1.
Recommended storage: -20°C, protect from light, stored under inert gas; in solvent: -80°C up to 6 months, -20°C up to 1 month.
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Each Sweat control has a different molarity. Sweat Control 1 is approximately 40mmol/L, Sweat Control 2 is approximately 70mmol/L, and Sweat Control 3 is approximately 130mmol/L.
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