Clinical Chemistry Controls
ABclonal Technology Ferritin Heavy Chain Rabbit
This gene encodes the heavy subunit of ferritin the major intracellular iron storage protein in prokaryotes and eukaryotes It is composed of 24 subunits of the heavy and light ferritin chains Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues A major function of ferritin is the storage of iron in a soluble and nontoxic state Defects in ferritin proteins are associated with several neurodegenerative diseases This gene has multiple pseudogenes Several alternatively spliced transcript variants have been observed but their biological validity has not been determined
Cayman Chemical Docosahexaenoyl SerotonIn 10mg
A hybrid molecule patterned after N-arachidonoyl serotonin; effects of docosahexaenoyl serotonin are unknown
LABSYSTEMS DIAGNOSTICS OY CAH Multilevel Controls in DBS format
NeoMass CAH Multilevel DBS Controls are used for quality assurance in determining the accuracy of the analytes androstenedione, cortisol, 11-deoxycortisol, 21-deoxycortisol, 17-hydroxyprogesterone and 21-hydroxyprogesterone in Dried Blood Spots (DBS). These DBS controls are prepared by using human blood and are available as a control set with 3 levels. The controls are handled and used in the same way as newborn DBS samples. It is recommended to use controls in duplicates at each level per run.
Cayman Chemical Cholesterol SulfatesodIM100mg
An endogenous component of cell membranes where it serves as a substrate for steroid synthesis, influences lipid metabolism, stabilizes cell membranes, regulates the activity of functional proteins, and plays a role in keratinocyte differentiation and development of the epidermal barrier
ABclonal Technology Cystatin A Rabbit mAb
The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins, and kininogens. This gene encodes a stefin that functions as a cysteine protease inhibitor, forming tight complexes with papain and the cathepsins B, H, and L. The protein is one of the precursor proteins of cornified cell envelope in keratinocytes and plays a role in epidermal development and maintenance. Stefins have been proposed as prognostic and diagnostic tools for cancer.
Cayman Chemical H4 PosItIve Control 12.5nmol
A PROTAC that drives FAK degradation binds to the FAK kinase domain (IC50 15.8 nM) and induces FAK degradation in A549 cells (DC50 1.3 nM) inhibits A549 cell migration and invasion at 100 nM reduces hepatic FAK levels in mice at 8 mg/kg
Cayman Chemical 7-dehydro Cholesterol 25g
An immediate precursor to cholesterol; accumulates in Smith-Lemli-Opitz syndrome (SLOS); highly susceptible to free radical oxidation, giving rise to several oxysterols that may be involved in the pathogenesis of SLOS; levels are increased in brain, liver, and serum in a rat model of SLOS induced by the DHCR7 inhibitor AY 9944; converted to vitamin D3 by UVB light ex vivo