Substrates
=O | 1g | 117545132](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502192947.JPG-250.jpg)
eMolecules 2096330-15-1 | 2-Dibromomethyl-5-nitrophenylboronic acid, pinacol ester | Combi-Blocks | MFCD19981555 | 420.890 | C13H16BBr2NO4 | 97.000 | CC1(C)OB(OC1(C)C)c1cc(ccc1C(Br)Br)[N+]([O-])=O | 1g | 117545132
2-Dibromomethyl-5-nitrophenylboronic acid, pinacol ester | Combi-Blocks | 2096330-15-1 | MFCD19981555 | 420.890 | C13H16BBr2NO4 | 97.000 | CC1(C)OB(OC1(C)C)c1cc(ccc1C(Br)Br)[N+]([O-])=O | 1g | 117545132
CPC Scientific Ac-Arg-Gly-Lys(Ac)-AMC (trifluoroacetate salt) 5MG
This peptide is the fluorogenic substrate for assaying histone deacetylase (HDAC) activity in a two-step enzymatic reaction. The assay consists of the initial lysine deacetylation by HDAC followed by the release of the fluorescent group by trypsin.ONE-LETTER SEQUENCE: Ac-RGK(Ac)-AmcMOLECULAR FORMULA: C28H40N8O7MOLECULAR WEIGHT:600.68STORAGE CONDITIONS: -20 5C, CAS REGISTRY NUMBER: [660846-97-9], RESEARCH AREA: MiscellaneousREFERENCES: D.Wegener et al., Chem. Biol., 10, 61 (2003)
Biotium NucView 530 Caspase-3 Substrate, 1 mM in DMSO, Trial Size
NucView Caspase-3 Substrates are novel fluorogenic substrates for real-time or endpoint detection of apoptosis in live cells. The non-toxic, no-wash substrates do not inhibit caspase-3 unlike other caspase substrates or FLICA assays permitting multiday analysis. Consisting of a high-affinity DNA dye linked to a DEVD caspase-3 substrate moiety, the cell permeable non-fluorescent substrate is cleaved by caspase-3 in apoptotic cells to emit fluorescence, allowing detection of both caspase-3 activity and apopototic nuclear morphology. Suitable for flow cytometry, fluorescence microscopy, or live cell imaging systems, staining is compatible with fixation and permeabilization for immunostaining. NucView 488 is validated in over 100 cell types and 200 publications. Available with blue (NucView 405), green (NucView 488), or red (NucView 530) fluorescence, in DMSO or PBS for DMSO-sensitive cells, and as kits with apoptosis or necrosis probes. NucView technology is covered by U.S. patents.
Medchemexpress LLC HER2/CD340 Human B 5ug | 5ug
The HER2/CD340 protein is a dynamic tyrosine kinase that is essential in the neuregulin receptor complex and regulates microtubule dynamics Upon activation it triggers the MEMO1-RHOA-DIAPH1 pathway inhibits GSK3B and promotes the association of APC and CLASP2 on the cell membrane to achieve microtubule stabilization HER2/CD340 Protein Human (Biotinylated Domain 4 HEK293 His-Avi) is the recombinant human-derived HER2/CD340 protein expressed by HEK293 with C-His-Avi labeled tag
Abcam 8-Octanoylo x ypyrene-1,3,6-trisulfonic acid trisodium salt, 25MG
MW 650.6 Da. Highly polar and water soluble lipase substrate derived from HPTS (pyranine), which forms tight micelles in aqueous solutions. Lipase activity can be established by measuring the fluorescence kinetics following the increase in emission of HPTS (hydroxypyrene trisulfonic acid). Due to its low pKa value (7.3), it is partially dissociated to form an anion that shows strong absorption (max: 460 nm) and maximum intensity at 520 nm. Fluorescence intensity is pH dependent between Ex:440-480 nm and reaches the isosbestic point at Ex: 415 nm.
The product is subject to the following: Abcam Restricted Use Statement
Biotium Aquaphile™ Coelenterazine h, lyophilized solid
Aquaphile coelenterazine native is a bioluminescence substrate in a special formulation format that is readily dissolved in water or PBS buffer for in vivo use.Properties: Yellow solid soluble in water or PBS buffer; Store at -20°C and protect from light; C26H21N3O3; MW: 423; [55779-48-1].
Enzo Life Sciences MeOSuc-AAPV-pNA (5mg). CAS: 70967-90-7
Highly sensitive substrate for human and mouse neutrophil elastase (leukocyte elastase) and neutrophil proteinase 3 (PR-3, myeloblastin), but not cathepsin G nor chymotrypsin. This substrate can be used for in vitro assays with purified enzyme, or with biological fluids or conditioned medium. Hydrolysis of the substrate can be detected at 405-410 nm. Purity: ≥98%. Solubility: Soluble in DMSO (>20 mM) or methanol (1 mg/mL). Long Term Storage: -20°C.
Enzo Life Sciences Ac-IEPD-AMC (5mg)
Fluorogenic substrate for caspase-8 and granzyme B. Ex.: 360 nm, Em.: 450 nm. The Km of recombinant human granzyme B for Ac-IEPD-AMC is 160 µM, with a Vmax about eight-fold lower than that of Ac-IEPD-pNA (BML-P133). Alternative name: Caspase 8 substrate (fluorogenic), Granzyme B substrate (fluorogenic). Purity: ≥95%. Solubility: Soluble in DMSO. Long Term Storage: -20°C.
Enzo Life Sciences Digoxigenin-UTP, alkali-stable (250nmol)
Digoxigenin-UTP can replace UTP in reactions catalyzed by T3, T7 or SP6 RNA polymerases. The digoxigenin-labeled RNA transcripts produced by these reactions are suitable for a wide range of applications such as nucleic acid hybridization, sequencing, and genome analysis. The transcription reaction produces multiple RNA copies of the DNA template(s) during a short incubation period. RNA probes offer higher target specificity and greater sensitivity than the corresponding DNA-DNA hybrids. The single-stranded RNA probes offer selectivity unavailable with double-stranded DNA probes, because they are strand-specific. Furthermore, RNA probes hybridize much more efficiently to target molecules than DNA probes because there is no self-hybridization. Alternative name: Digoxigenin-11-UTP. Concentration: 10mM. Quantity: 25µl. Purity: ≥93% (HPLC). Formulation: Liquid. Solution in water.
Seracare Life Sciences Inc STABLEDAB HRP SUBSTRATE KIT
StableDAB remains active and does not precipitate over a 2 week period at use dilution; at ambient temperature it remains stable for 1 week. At 2-8C it remains stable for 2 weeks. Diaminobenzidine (DAB)is the most commonly used substrate for the histochemical detection of peroxidase. It reacts with HRP to produce an insoluble brown precipitate and can be used in staining tissues and on membranes. The main disadvantage of DAB is that it must be used immediatley to avoid reaction with the enzyme. KPL's StableDAB overcomes this disadvantage and can remain ready-to-use for 2 weeks after preparation. Kit includes StableDAB Peroxidase Substrate and Buffer Concentrate.Smooth muscle actin in skin tissue, using streptavidin peroxidase stained with StableDAB, Contrast BLUE counterstain.
Aat Bioquest D-Luciferin potassium salt CAS 115144-35-9 (100 mg)
Luciferin is the most popular and versatile bioluminescent substrate. This catalog is for 100 mg.
Aat Bioquest D-Luciferin potassium salt CAS 115144-35-9 (1 g)
Luciferin is the most popular and versatile bioluminescent substrate. This catalog is for 1 g.
Cayman Chemical LIpase Substrate 1.2mL
This assay kit provides the convenience of an all-inclusive cell-based reporter assay system for M-CSFR signaling. In addition to Reporter Cells included are an optimized culture medium for use in reviving the cryopreserved cells a culture medium for use in preparing test sample treatments the physiological activator M-CSF as a positive control Luciferase Detection Reagents and a cell culture-ready assay plate
Bioworld 4-Methylumbelliferyl-á-D-Glucopyranoside, 250 mg
4-Methylumbelliferyl-α-D-glucopyranoside[4-Methylumbelliferyl-α-D-Glucoside]C16H18O8MW 338.3Fluorescent substrate for -α-D-Glucosidase.Purity: >98%. 4-Methylumbelliferone <50ppm.Soluble in 2% acetone/water 1:1.CAS 17833-43-1This product is sold for laboratory research use only.