Substrates
Medchemexpress LLC Z-Ala-Arg-Arg-AMC | 90468-18-1 | 98.4% | 692.77 g/mol | C33H44N10O7 | 5 MG
Z-Ala-Arg-Arg-AMC is a fluorogenic peptide substrate for quantifying trypsin-like activity of the proteasome. Proteolytic cleavage releases 7-amino-4-methylcoumarin (AMC), producing a fluorescence signal used in biochemical and enzymatic assays.
- Generates a fluorescent AMC signal upon proteolytic cleavage.
- Designed for measuring trypsin-like proteasome activity.
- High purity (~98.4%) suitable for research assays.
- Supplied as a solid; soluble in DMSO at about 50 mg/mL with ultrasonic assistance.
- Store sealed, away from moisture, under recommended low-temperature conditions.
- Available in small research-scale quantities (mg scale).
Sino Biological Peptide Substrates: Modified AKT Substrate
The Modified AKT Substrate peptide sequence (modified-CKRPRAASFAE) is based on the N-terminus of GSK3.
Abcam AFC (7-Amino-4-trifluoromethylcoumarin), Fluorescent marker
Fluorescent marker. Substrate for fluorogenic enzyme assays.
The product is subject to the following: Abcam Restricted Use Statement
Avanti Polar Lipids L-α-phosphatidylinositol-4,5-bisphosphate (Brain, Porcine) (ammonium salt), 383907-42-4, MFCD28901390, 10 mg
Formula Weight: 1096.385, Purity >99%, Stability: 3 Months, Storage Temperature: -20°C. Although PI(4,5)P2 is a minor component of cell membranes, it plays a critical role as a substrate for a number of important signaling proteins. PI(4,5)P2 is an intermediate in the IP3/DAG pathway where it is hydrolyzed by phospholipase C to liberate the second messengers, inositol 1,4,5-triphosphate (IP3) and diacylglycerol (DAG). PI(4,5)P2 is also a substrate for PI 3-kinase where it is phosphorylated to PI(3,4,5)P3, an activator of downstream signaling components such as the protein kinase AKT.
eMolecules Apollo Scientific D-Luciferin potassium salt 100mg 562533490 BIL1800 0 000 115144-35-9 MFCD00044928 318 410 C11H7KN2O3S2
Apollo Scientific D-Luciferin potassium salt 100mg 562533490 BIL1800 0 000 115144-35-9 MFCD00044928 318 410 C11H7KN2O3S2
Cayman Chemical TrnsglutamInase asy Substr 1ea
Transglutaminase Assay Substrate 1 has been tested and formulated to work exclusively with Cayman’s Transglutaminase Activity Assay Kit (Item No. 702250).
Cayman Chemical Abl SubstrAT PeptIdetrIflu 5mg
A peptide substrate for Abl; selectively phosphorylated by Abl over c-Src kinase at 20 µM; has been used to quantify Abl kinase activity in vitro
LifeSensors UBIQUITIN AMC 50UG
Ubiquitin-AMC is prepared via the conjugation of the C-terminus of mature, Ubiquitin with 7-amino-4-methylcoumarin (AMC). This conjugation quenches the intrinsic fluorescence of AMC.
Sino Biological Lipid Substrates: DLG (Dilauroyl-sn-glycerol)
The substrate solution used for assaying Diacylglycerol kinases.
Medchemexpress LLC Glycyl-L-proline 7-amido-4-methylcoumarin hydrobromide | 115035-46-6 | MFCD00152092 | 98.7% | 410.26 g·mol⁻¹ | C17H20BrN3O4 | 5 MG
Glycyl-L-proline 7-amido-4-methylcoumarin hydrobromide (CAS 115035-46-6) is a fluorogenic dipeptide substrate used to measure dipeptidyl peptidase IV (DPP-IV) activity. Enzymatic cleavage releases the fluorescent 7-amido-4-methylcoumarin (AMC) reporter, enabling sensitive continuous or end-point assays in biochemical and enzymatic studies. Supplied as an off-white to light yellow solid with high reported purity for research use.
- Specific fluorescent substrate for detecting DPP-IV activity.
- Releases 7-amido-4-methylcoumarin for sensitive fluorescence detection.
- Suitable for continuous or end-point enzyme assays.
- Compatible with standard fluorescence readers (abs/em ~353/442 nm).
- Supplied as a solid with high reported purity for biochemical use.
Apexbio Technology LLC Boc-Lys(Ac)-AMC 233691-67-3 250mg
Boc-Lys Ac -AMC (CAS 233691-67-3) is a fluorescently labeled peptide substrate designed for analyzing enzymatic activity of histone deacetylases (HDACs) It enables monitoring of HDAC-mediated deacetylation reactions Boc-Lys Ac -AMC exerts its biological activity primarily through acting as a fluorogenic substrate for HDACs where deacetylation leads to subsequent fluorescence release following proteolytic cleavage Based on these properties Boc-Lys Ac -AMC holds research potential in biochemical assays and drug screening studies for characterizing HDAC enzyme kinetics and assessing inhibitor potency related to epigenetic modulation
Enzo Life Sciences Chk 1 & 2 substrate (1mg)
This peptide sequence, KKKVSRSGLYRSPSMPENLNRPR, corresponds to amino acids 206-225 of the phosphatase CDC25C, which is a phosphorylation target of Chk1 on Ser216. The addition of three N-terminal lysines allows the peptide to be used in phosphocellulose kinase assays. Both Chk1 and Chk2 will phosphorylate this peptide. Alternative name: CDC25C (206-225). Long Term Storage: -20°C.
Electron Microscopy Sciences EMS Substrate Gold Coated Round Coverslips, 16 mm
EMS offers a variety of economically priced coated substrates. All coatings are deposited under vacuum using electron beam evaporation. These high quality substrates are coated with 500 Angstroms (50 nm) of gold, with a thin chromium adhesion layer (2-7 nm) between the glass and coating. All substrates are pre-cleaned using an ion source for quality assurance. Autoclavable. Packed in a cleanroom. Shipped in X0 Gel-Pak.
Dimensions: 16 mm
Material: Borosilicate glass
Selleck Chemical LLC Coumarin 6 S5170-25mg
Coumarin 6 is a fluorescent dye frequently used to facilitate the traceability of drug delivery systems in vitro