Substrates
Medchemexpress LLC Z-Gly-Gly-Arg-AMC | 66216-78-2 | 99.9% | 579.60 | 50 MG
Z-Gly-Gly-Arg-AMC is a thrombin-specific fluorogenic substrate used for testing thrombin generation in PRP and platelet-poor plasma (PPP) (Ex/Em = 390/480 nm).
- Thrombin-specific fluorogenic substrate.
- Suitable for testing thrombin generation in PRP and platelet-poor plasma (PPP).
- Excitation/Emission wavelengths: 390/480 nm.
CPC Scientific Ac-Asp-Glu-Asp(EDANS)-Glu-Glu-Abu-psi-(COO)Ala-Ser-Lys(DABCYL)-NH2 (trifluoroacetate salt) 0.5MG
A HCV protease substrate that incoporates an ester bond between residues P1 and P1. Due to ready transesterification of the scissile bond to the acyl-enzyme intermediate, this substrate shows very high kcat/Km values, enabling detection of activity with subnanomolar nonstructural protein 3 (NS3 protease) concentrations. It is widely used for the continuous assay of NS3 protease activity. Substrate cleavage is proportional to the enzyme concentration with a detection limit for NS3 between 1 nM and 250 pM. Upon cleavage of this substrate, fluorescence can be monitored at Abs/Em = 355/500 nm. As an internally quenced fluorogenic substrate, it can be used to monitor HCV NS3 protease activity.SEQUENCE: Ac-Asp-Glu-Asp(EDANS)-Glu-Glu-Abu-psi-(COO)Ala-Ser-Lys(DABCYL)-NH2 (trifluoroacetate salt)ONE-LETTER SEQUENCE: Ac-DED(EDANS)-EE-Abu-psi-(COO)AS-K(DABCYL)-NH2MOLECULAR FORMULA: C68H89N15O25S1MOLECULAR WEIGHT: 1548.6STORAGE CONDITIONS: -20 5 CCAS REGISTRY NUMBER: SYNONYMS: Ac-
Gold Biotechnology Inc D Luciferin Potassium 500mg
L uciferin is a common bioluminescent reporter used for in vivo imaging of the expression of luciferase This water soluble substrate for the firefly luciferase enzyme utilizes ATP and Mg2 as cofactors to emit a characteristic yellow-green emission in the presence of oxygen which shifts to red light in vivo at 37 C Through the utilization of ATP the reaction can be further used to indicate the presence of energy or life in order to function as a life-death stain
Cayman Chemical Abl Substrate Peptide triflu
A peptide substrate for Abl; selectively phosphorylated by Abl over c-Src kinase at 20 µM; has been used to quantify Abl kinase activity in vitro
Cayman Chemical AMC Arachidonoyl Amide
A fluorometric FAAH substrate used for enzyme activity measurement; release of the fluorescent AMC (ex/em = 360/465 nm) allows for fast and convenient measurement of FAAH activity
Abcam CENTA, beta-lactamase substrate, Yellow chromogenic beta-lactamase substrate, 10MG
MW 535.6 Da, Purity >98%. Yellow chromogenic β-lactamase substrate. Hydrolyses readily in the presence of all β-lactamases except for Aeromonas hydrophila metalloenzyme. Suitable for kinetic studies, the detection of the enzymes in crude extracts and chromatographic fractions. Absorbs light at 346 nm (Δε = -2500 M-¹ cm-¹) or 405 nm (Δε = +6400 M-¹ cm-¹).
The product is subject to the following: Abcam Restricted Use Statement
Cayman Chemical Gly-Gly-AMC 1mg
A fluorogenic peptide substrate; used to assess the activity of bacterial proteases from P. aeruginosa and S. aureus; enzyme activity can be quantified by fluorescent detection of free AMC (also known as 7-amino-4-methylcoumarin), which is excited at 340-360 nm and emits at 440-460 nm
Medchemexpress LLC Boc-Gly-Lys-Arg-AMC | 109358-48-7 | 616.71 | 25 MG
Boc-Gly-Lys-Arg-AMC is a polypeptide identified through peptide screening, a research tool that primarily uses immunoassay to pool active peptides. This method is applicable for protein interaction, functional analysis, and epitope screening, particularly in agent research and development.
- Identified through peptide screening
- Utilizes immunoassay to pool active peptides
- Applicable for protein interaction studies
- Suitable for functional analysis
- Useful for epitope screening
- Valuable in agent research and development
- For research use only
Medchemexpress LLC Carboxybenzoyl-leucyl-arginine 7-amido-4-methylcoumarin | 156192-32-4 | 99.2% | 578.66 g/mol | C30H38N6O6 | 5 MG
Z-Leu-Arg-AMC is a fluorogenic peptide substrate for assaying cysteine proteases such as cathepsin K. It consists of a carboxybenzoyl (Z)-protected leucyl-arginine linked to 7-amido-4-methylcoumarin (AMC); enzymatic cleavage releases fluorescent AMC for sensitive kinetic measurements. Supplied as a solid or as a 10 mM solution in DMSO for research use only.
- Sensitive fluorogenic reporter released on protease-mediated cleavage.
- Suitable for cathepsin K and other cysteine protease activity assays.
- High reported purity for consistent, reproducible results.
- Available as solid or pre-prepared DMSO solution for flexible use.
- Soluble in DMSO; handle and store according to standard reagent recommendations.
Sino Biological Peptide Substrates: Amyloid Beta Peptide (1-42)
The Amyloid Beta Peptide (42 aa) sequence is DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA. It is produced synthetically and treated with 1,1,1,3,3,3-Hexafluoro-2-propanol (HFIP) prior to drying which breaks down pre-formed fibrils and monomerizes the peptide.
Medchemexpress LLC Ac-IETD-AFC | 211990-57-7 | 99.3% | 729.65 | 10 MG
Ac-IETD-AFC is a fluorogenic substrate for caspases-8, -3, and -10, as well as granzyme B. This product is intended for research use only and is not sold to patients.
- Fluorogenic substrate for caspase-8, caspase-3, caspase-10, and granzyme B
- Suitable for enzyme labeling and fluorescence studies
- Used in apoptosis and caspase research
- Excitation wavelength less than 380 nm
- Emission wavelength 496-570 nm (green)
Medchemexpress LLC Z-Gly-Gly-Arg-AMC acetate | 2070009-61-7 | 99.84% | 639.66 | 50 MG
Z-Gly-Gly-Arg-AMC acetate is a thrombin-specific fluorogenic substrate primarily used for testing thrombin generation in both platelet-rich plasma (PRP) and platelet-poor plasma (PPP). This compound, characterized by excitation/emission wavelengths of 390/480 nm, is provided as a solid, typically white to off-white, and is strictly for research applications.
- Thrombin-specific fluorogenic substrate
- Suitable for thrombin generation assays in PRP and PPP
- Exhibits excitation at 390 nm and emission at 480 nm
- Supplied as a white to off-white solid
- Intended for research use only
Abcam 4-Trifluoromethylumbelliferyl oleate, 10MG
MW 494.6 Da. Fluorescent lipase substrate. Releases highly fluorescent 4-trifluoromethylumbelliferone upon hydrolysis. 4-trifluoromethylumbelliferone is insensitive to pH making it suitable for use in food analysis.
The product is subject to the following: Abcam Restricted Use Statement
AdipoGen Ac-Arg-Leu-Arg-AMC (5 mg)
Ac-Arg-Leu-Arg-AMC (5 mg), AdipoGen Life Sciences. Chemical. CAS: 929903-87-7 (free base). Formula: C30H46N10O6 . C2HF3O2. MW: 642.8 . 114.0. Fluorogenic tri-peptide substrate for measuring the trypsin-like peptidase activity of the 20S proteasome. It is cleaved exclusively at the amide R-AMC bond to release fluorescent product. Shows low Km and high specific activity. Excitation: 380nm. Emission: 460nm. This substrate is useful for inhibitor screening and kinetic analysis.
Abcam PAP-AMC, Tyrosinase substrate, Fluorogenic tyrosinase substrate, 100UG
MW 310.3 g/mol, Purity >98%. Fluorogenic tyrosinase substrate. Achieve your results faster with highly validated, pure and trusted compounds.
The product is subject to the following: Abcam Restricted Use Statement