Substrates
MEDCHEMEXPRESS LLC Gly-Phe-AMC | 201852-70-2 | 98.8% | 379.41 | 1 MG
Gly-Phe-AMC is a fluorogenic peptide substrate composed of a peptide sequence of glycine and phenylalanine, linked to the fluorophore AMC. It also functions as a cathepsin C substrate and is widely used to detect the activity of various proteases.
- Fluorogenic peptide substrate
- Functions as a cathepsin C substrate
- Widely used to detect the activity of various proteases
MEDCHEMEXPRESS LLC L-Prolinamide, L-lysyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)- (diTFA) | 133066-53-2 | 97.7% | 628.52 | 25 MG
Lys-Pro-AMC diTFA is a fluorogenic substrate utilized for the detection and measurement of specific enzyme activities. This compound appears as a white to off-white solid.
- Fluorogenic substrate for enzyme activity detection.
- Utilized for the measurement of specific enzyme activities.
- Supplied as a white to off-white solid.
- Soluble in H₂O at 100 mg/mL (159.10 mM) with sonication.
- Soluble in DMSO at 100 mg/mL (159.10 mM) with sonication (use newly opened DMSO due to hygroscopic nature).
MEDCHEMEXPRESS LLC Ac-Tyr-Val-Ala-Asp-AMC | 149231-65-2 | 665.69 | 1 MG
Ac-YVAD-AMC is a potent caspase inhibitor that effectively suppresses bacteria-induced cell death, specifically within hypersensitive response (HR) cells. This compound is valuable in research for studying cellular apoptosis and inflammatory processes.
- Inhibits caspase activity
- Suppresses bacteria-induced cell death in HR cells
- Useful for apoptosis research
- Supports studies on inflammatory pathways
DIAPHARMA GROUP INC Chromogenix S-2765, 25 mg
Chromogenix S-2765 is a chromogenic substrate for determination of Factor Xa activity. It is also very sensitive to trypsin. S-2765 is suitable for measuring FXa inhibition in heparin anti-Xa assays and antithrombin anti-Xa assays.
Vector Laboratories VECTOR Blue Alkaline Phosphatase (AP) Substrate Kit 200 ml
VECTOR Blue Alkaline Phosphatase (AP) Substrate Kit produces a blue, heat-stable reaction product. This chromogen can be used singly or in combination with other alkaline phosphatase or peroxidase substrates for multiple label applications. Sections stained with the VECTOR Blue substrate can be dehydrated, cleared, and permanently mounted; however, non-xylene clearing agents and non-xylene based mounting media (such as VectaMount) must be used because the reaction product is soluble in xylene. VECTOR Blue can also be used on blots in applications such as ELISPOT, singly or in combination with a peroxidase substrate such as AEC. The stock solutions in this kit are provided in convenient dropper bottles, with sufficient volume for 200 ml working solution.
AnaSpec 520 MMP FRET Substrate I, Sensitive FRET Assay Tool, High Purity ≥95%, 0.1 mg
The 520 MMP FRET Substrate I is a sensitive fluorogenic peptide specially designed for detecting Matrix Metalloproteinases (MMPs). Its unique FRET mechanism allows rapid enzymatic activity measurements, particularly for MMP-13. This substrate excels in research areas like cancer and apoptosis, offering a reliable way to quantify protease activity with clear fluorescent readouts, differentiate enzymatic activity, and ensure reliable results for scientific studies.
MEDCHEMEXPRESS LLC D-luciferin potassium | 115144-35-9 | 100.0% | 318.41 g·mol^-1 | C11H7KN2O3S2 | 1G
D-Luciferin potassium is the water-soluble potassium salt of D-luciferin, the natural substrate for firefly luciferase. It produces yellow-green bioluminescence upon ATP-dependent oxidation and is used for biochemical luciferase assays, cell-based reporter assays, and in vivo imaging. The compound is supplied as a solid powder suitable for preparation of aqueous solutions for experimental use.
- Water-soluble potassium salt for easy aqueous formulation.
- Suitable for bioluminescent luciferase assays and imaging.
- High analytical purity (manufacturer lists 99.97%).
- Molecular weight 318.41 g·mol⁻¹ and formula C11H7KN2O3S2.
- Available in multiple pack sizes including 1 g for laboratory use.