Substrates
MilliporeSigma™ Calbiochem™ Z-Phe-Arg-7-amido-4-methylcoumarin, Hydrochloride
Used as substrate for fluorogenic assay of plasma and glandular kallikreins. MilliporeSigma™; Calbiochem™ Z-Phe-Arg-7-amido-4-methylcoumarin, Hydrochloride also acts as substrate for cathepsin B, cathepsin L, and papain.
BD Ac-DEVD-AMC Caspase-3 Substrate
Synthetic tetrapeptide fluorogenic substrate for Caspase-3 (CPP32) containing the amino acid sequence of the PARP cleavage site at Asp-216
BD Ac-DEVD-AFC Caspase-3 Substrate
Synthetic tetrapeptide substrate for caspase-3 containing the amino acid sequence which is the target for caspase-3-mediated proteolysis
R&D Systems™ Z-Leu-Arg-Gly-Gly-AMC
This item is in process of being discontinued.
Thermo Scientific Chemicals Cathepsin K Substrate (fluorogenic)
For cellular and molecular biology applications | 578.65 g/mol
Cayman Chemical MPO ChlorInatIon Substrate 1ea
A Clk1 Clk2 and Clk4 inhibitor (IC50s 8 20 and 12 nM respectively) selective for these kinases over Clk3 (IC50 >3000 nM) as well as DYRK1A DYRK1B DYRK2 HIPK1 and HIPK3 (IC50s 213 956 1309 187 and 159 nM respectively) but does inhibit HIPK2 (IC50 23 nM)
Cayman Chemical SPHK Substrate 1ea
A PD-1/PD-L1 interaction inhibitor (IC50 6.3 nM) increases T cell proliferation in a PD-L1-overexpressing CT26 colon cancer cell and T cell co-culture at 20 nM promotes T cell infiltration into an in vitro PD-L1-overexpressing murine Lewis lung carcinoma tumor matrix at 20 and 80 nM reduces tumor growth and promotes CD8 and CD4 T cell tumor infiltration in a PD-L1-overexpressing murine Lewis lung carcinoma model at 20 mg/kg
Sigma Aldrich Fine Chemicals Biosciences SIGMA ALDRICH FINE CHEMICALS BIOSCIENCES
NC3953864 AZOALBUMIN PROTEASE SUBSTR 5G
