Isotopically Labeled Compounds
Medchemexpress LLC Ethyl maltol-d5 | 4940-11-8 | 99.0% | 145.17 | 1 MG
Ethyl maltol-d5 is the deuterium labeled Ethyl maltol. Ethyl maltol is an orally active and important food additive and flavor enhancer. It is less toxic to rats and dogs and can enhance copper-mediated cytotoxicity and induce apoptosis in lung epithelial cells. For research use only.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes have potential to affect the pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC DL-Valine-d8 | 203784-63-8 | 100.0% | 125.20 | 100 MG
DL-Valine-d8 is the deuterium labeled DL-Valine. It is for research use only and not sold to patients. This compound is used for various applications in chemical analysis.
- This compound can be used as a tracer.
- This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Morpholine-d4 hydrochloride | 1115228-35-7 | 127.61 | 100 MG
Morpholine-d4 hydrochloride is the deuterium labeled Morpholine hydrochloride. This compound can be used as a tracer or as an internal standard for quantitative analysis. It is suitable for analysis by NMR, GC-MS, or LC-MS.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Glipizide-d11 | 1189426-07-0 | 96.4% | 5 MG
Glipizide-d11 is the deuterium labeled Glipizide. Glipizide (CP 2872; K 4024) is a potent, orally active, sulfonylurea class anti-diabetic agent used for type 2 diabetes mellitus research, but not for type 1. Glipizide acts by partially blocking ATP-sensitive potassium (KATP) channels among β cells of pancreatic islets of Langerhans.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Deuteration can impact the pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC Benzene-2,3,5,6-d4-sulfonamide, 4-amino-N-(5-methyl-3-isoxazolyl)- | 1020719-86-1 | 99.3% | 5 MG
Sulfamethoxazole-d4 (Ro 4-2130-d4) is a deuterium-labeled version of Sulfamethoxazole, a sulfonamide antibiotic with broad antibacterial activity. It inhibits bacterial folate metabolism by competing with 4-Aminobenzoic acid (PABA) to affect dihydropteroate synthetase and dihydropteroate reductase. This compound is used in research for conditions such as urinary tract infections (UTIs), prostatitis, and bronchitis. Deuterium labeling incorporates stable heavy isotopes into the drug molecule, which can serve as a tracer for quantitation during drug development and potentially affect pharmacokinetic and metabolic profiles.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Adenosine-1′-13C | 201996-55-6 | 96.3% | 1 MG
Adenosine-1′-13C is the 13C labeled Adenosine. Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular physiology and is for research use only.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Incorporates stable heavy isotopes into drug molecules for quantitation
- Has potential to affect pharmacokinetic and metabolic profiles of drugs
Medchemexpress LLC D-Glucose-d12-1 | 89798-27-6 | 99.4% | 100 MG
D-Glucose-d12-1 is a deuterium-labeled D-Glucose, which is a monosaccharide essential for general metabolism and acts as a critical signaling molecule in cellular metabolic status and stress response. Deuteration can influence the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Bromhexine-d3 hydrochloride | 611-75-6 | 99.0% | 1 MG
Bromhexine-d3 (hydrochloride) is a deuterium-labeled Bromhexine (hydrochloride) that functions as a potent and specific TMPRSS2 protease inhibitor with an IC50 of 0.75 μM. It holds potential for preventing and managing SARS-CoV-2 infection and also acts as an autophagy agonist. Additionally, Bromhexine hydrochloride serves as a mucolytic cough suppressant, suggesting its utility in various respiratory conditions. This product is intended for research use only.
- Deuterium labeled Bromhexine (hydrochloride)
- Potent and specific TMPRSS2 protease inhibitor
- Can prevent and manage SARS-CoV-2 infection
- Autophagy agonist
- Mucolytic cough suppressant
- Used as a tracer or internal standard for quantitative analysis
Medchemexpress LLC D-Glucose-13C2 | 201741-04-0 | 98.0% | 100 MG
D-Glucose-13C2 is the 13C labeled D-Glucose, a critical monosaccharide for general metabolism and a signaling molecule related to cellular metabolic status and stress response. This compound can be used as a tracer or an internal standard for quantitative analysis.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Istradefylline-13C,d3 | 2749234-46-4 | 98.3% | 388.44 | 50 MG
Istradefylline-13C,d3 is the 13C- and deuterium labeled Istradefylline. It is a very potent, selective and orally active adenosine A2A receptor antagonist with Ki of 2.2 nM in experimental models of Parkinson's disease.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Clotrimazole-d10 | 23593-75-1 | 97.5% | 354.90 | 1 MG
Clotrimazole-d10 is a deuterated labeled form of Clotrimazole (HY-10882), which is an imidazole derivative known for its antifungal properties and as a CYP (cytochrome P450) inhibitor. This compound also exhibits antibacterial activity, making it versatile for various research applications.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Mavacamten-d5 | 2453251-00-6 | 98.6% | 278.36 | 1 MG
Mavacamten-d5 is a deuterium-labeled version of Mavacamten (HY-109037), an orally active modulator of cardiac myosin. This compound is intended for research use only.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes are incorporated into drug molecules for quantitation during drug development.
- Deuteration can affect the pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC Glycine-2-13C | 20220-62-6 | MFCD00037550 | 99.3% | 76.06 g/mol | H2N13CH2COOH | 5mg
Glycine-2-13C is the 13C-labeled Glycine Glycine is an inhibitory neurotransmitter in the CNS and also acts as a co-agonist along with glutamate facilitating an excitatory potential at the glutaminergic N-methyl-D-aspartic acid (NMDA) receptors
Cambridge Isotope Laboratories DOPAMINE:HCL (2-(3,4-DIHYDROXYPHENYL)- ETHYLAMINE:HCL) (1-13C, 99%), 0.05 G
DOPAMINE:HCL (2-(3,4-DIHYDROXYPHENYL)- ETHYLAMINE:HCL) (1-13C, 99%), 0.05 G
Sigma Aldrich Fine Chemicals Biosciences Aldicarb-(N-methyl-13C,d3 carbamoyl-13C) >=98 atom %, >=98% (CP) | 1261170-75-5 | MFCD17677362 | 25MG
Aldicarb-(N-methyl-13C,d3 carbamoyl-13C) >=98 atom %, >=98% (CP) | Purity: >=98% (CP) | Mol Wt: 195.27 | 1261170-75-5 | MFCD17677362 | 25MG