Isotopically Labeled Compounds
Medchemexpress LLC Propan-2-amine-d6 h 50mg
Propan-2-amine-d6 hydrochloride is the deuterium labeled Propan-2-amine[1]
Medchemexpress LLC Exatecan-d5 mesylate | 2819276-88-3 | 99.8% | 536.58 | 50 MG
Exatecan-d5 mesylate is a deuterium-labeled version of Exatecan mesylate. It acts as a DNA topoisomerase I inhibitor, with an IC50 of 2.2 μM (0.975 μg/mL), and is used in cancer research.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis using NMR, GC-MS, or LC-MS.
Medchemexpress LLC Z,Z-Dienestrol-d6 | 91297-99-3 | 99.8% | 272.37 | 1 MG
Z,Z-Dienestrol-d6 is the deuterium labeled Z,Z-Dienestrol. This compound can be used as a tracer and as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS. Deuteration has gained attention due to its potential to affect the pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC Methyl palmitate-13C16 | 112-39-0 | 286.33 | 5 MG
Methyl palmitate-13C16 is the 13C labeled Methyl palmitate. Methyl palmitate, an acaricidal compound occurring in green walnut husks, inhibits phagocytic activity and immune response. Methyl palmitate also possesses anti-inflammatory and antifibrotic effects.
- Used as a tracer.
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules as tracers for quantitation during the drug development process.
Cambridge Isotope Laboratories CAFFEINE (2-13C, 99%; 1,3-15N2, 98%+), 0.1 G
CAFFEINE (2-13C, 99%; 1,3-15N2, 98%+), 0.1 G
Cambridge Isotope Laboratories UREA (13C, 99%; 15N2, 98%+), 0.5 G, 78405-35-3
UREA (13C, 99%; 15N2, 98%+), 0.5 G, 78405-35-3
Medchemexpress LLC Nortriptyline hydrochloride | 894-71-3 | 99.98% | 100 MG
Nortriptyline hydrochloride is the main active metabolite of Amitriptyline, classified as a tricyclic antidepressant. It functions as a potent autophagy inhibitor and demonstrates anticancer effects, intended for research use only.
- Inhibits the Norepinephrine transporter (NET, SLC6A2)
- Reduces viability of bladder cancer cells
- Induces cell cycle arrest
- Induces apoptosis in bladder cancer cells
- Blocks reuptake of Norepinephrine more potently than Serotonin
Cambridge Isotope Laboratories DIETHYL MALONATE (2-13C, 99%), 1 G, 67035-94-3
DIETHYL MALONATE (2-13C, 99%), 1 G, 67035-94-3
Cambridge Isotope Laboratories L-ASPARTIC ACID (1,4-13C2, 99%), 0.5 G, 101247-29-4
L-ASPARTIC ACID (1,4-13C2, 99%), 0.5 G, 101247-29-4
Cambridge Isotope Laboratories TRIETHYL ORTHOACETATE (1,2-13C2, 99%), 0.5 G
TRIETHYL ORTHOACETATE (1,2-13C2, 99%), 0.5 G
Cayman Chemical SalIcylIc AcId-d4 5mg
An internal standard for the quantification of salicylic acid by GC- or LC-MS
Medchemexpress LLC Glycerol-d3 | 7325-16-8 | >98% | 500 MG
Glycerol-d3 is the deuterium labeled Glycerol. Glycerol is utilized in sample preparation and gel formation for polyacrylamide gel electrophoresis. It can be used as a tracer and as an internal standard for quantitative analysis through NMR, GC-MS, or LC-MS. Deuteration of drug molecules, which involves incorporating stable heavy isotopes of hydrogen, carbon, and other elements, can impact their pharmacokinetic and metabolic profiles.
- Used in sample preparation and gel formation for polyacrylamide gel electrophoresis.
- Can be used as a tracer and internal standard for quantitative analysis.
- Useful for NMR, GC-MS, or LC-MS applications.
- Deuteration can impact pharmacokinetic and metabolic profiles of drug molecules.
Medchemexpress LLC Canrenone-d6 (Aldadiene-d6) | 976-71-6 | 98.8% | 1 MG
Canrenone-d6 is the deuterium-labeled version of Canrenone. Canrenone (Aldadiene) is an aldosterone antagonist frequently used as a diuretic agent. It is intended for research use only.
- Used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes of hydrogen, carbon, and other elements are incorporated into drug molecules, primarily as tracers for quantitation during drug development.
- Deuteration can potentially influence the pharmacokinetic and metabolic profiles of drugs.
Cayman Chemical L-KynurenIn-d4 500ug
An internal standard for the quantification of kynurenine by GC- or LC-MS
Medchemexpress LLC Nortriptyline hydrochloride | 894-71-3 | 99.98% | 1 ML
Nortriptyline hydrochloride (Desmethylamitriptyline) is the main active metabolite of Amitriptyline, functioning as a tricyclic antidepressant. It also acts as a potent autophagy inhibitor and demonstrates anticancer effects.
- Potent autophagy inhibitor
- Anticancer effects
- Inhibits Norepinephrine transporter (NET, SLC6A2)
- Blocks Norepinephrine reuptake more potently than Serotonin
- Reduces viability and induces apoptosis in bladder cancer cells
- Inhibits bladder tumor growth in vivo