Isotopically Labeled Compounds
Medchemexpress LLC D18 | 2230218-36-5 | 98.8% | C21H28N6 | 1 MG
D18 is an immune modulator and acts as a TLR7/8 dual agonist. It increases PD-L1 expression through epigenetic regulation, sensitizing tumors to PD-1/PD-L1 blockade. This substance is also an ADC cytotoxin used for the synthesis of ADC HE-S2 (HY-144497) and exhibits strong immune activation and anti-tumor activity, commonly used in cancer research.
- Acts as a TLR7/8 dual agonist
- Increases PD-L1 expression through epigenetic regulation
- Sensitizes tumors to PD-1/PD-L1 blockade
- Utilized as an ADC cytotoxin for ADC HE-S2 synthesis
- Exhibits strong immune activation and anti-tumor activity
- Used in cancer research, including colon cancer
Cambridge Isotope Laboratories Acetone-D6 (D, 99.9%), 10 X 0.5Ml, 666-52-4
Acetone-D6 (D, 99.9%), 10 X 0.5Ml, 666-52-4
Medchemexpress LLC Uracil | 202407-06-5 | MDL-MFCD01073456 | 98.0% | 118.04 g/mol | 13C4H4 15N2O2 | 10 MG
Uracil-13C4,15N2 is an isotopically labeled uracil provided as a solid research standard for analytical and tracer applications. Four carbon atoms are 13C and two nitrogens are 15N; the material is supplied at high purity and intended for use in mass spectrometry, metabolic labeling, and tracer studies.
- Isotopically labeled with 13C4 and 15N2.
- High purity: 98.0%.
- Suitable for mass spectrometry and tracer studies.
- Available in small research quantities (10 MG).
- Supplied as a solid for convenient handling and storage.
Medchemexpress LLC Pristane-d40 | 16416-35-6 | 50 MG
Pristane-d40 is deuterium labeled Pristane. Pristane (Norphytane) is a naturally occurring hydrocarbon oil found in small quantities in many plants, various marine organisms, and is the most active component of mineral oil. It acts as a non-antigenic adjuvant and induces MHC class II-restricted, arthritogenic T cells in rats.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Cambridge Isotope Laboratories BROMOBENZENE (D5, 99.5%), 5 G, 4165-57-5
BROMOBENZENE (D5, 99.5%), 5 G, 4165-57-5
Medchemexpress LLC Squalene-d6 | 1875101-86-2 | 416.75 | 5 MG
Squalene-d6 (Super Squalene-d6) is a deuterium labeled Squalene. Squalene (Super Squalene) is an intermediate product in the synthesis of cholesterol, and shows several pharmacological properties such as hypolipidemic, hepatoprotective, antiatherosclerotic, cardioprotective, antioxidant, and antitumour activity.
- This compound can be used as a tracer.
- This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Epicoprostanol-d5 5mg
Epicoprostanol-d5 is the deuterium labeled Epicoprostanol Epicoprostanol is the compound found in adipocere[1][2]
Medchemexpress LLC D-Fructose-d7 | 100 MG
D-Fructose-d7 is the deuterium labeled D-Fructose. D-Fructose (D(-)-Fructose) is a naturally occurring monosaccharide found in many plants. For research use only. We do not sell to patients.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process.
- Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
Cambridge Isotope Laboratories AMMONIUM NITRATE (15N2, 98%+), 1 G, 43086-60-8
AMMONIUM NITRATE (15N2, 98%+), 1 G, 43086-60-8
Cambridge Isotope Laboratories URACIL (1,3-15N2, 98%), 0.25 G, 5522-55-4
URACIL (1,3-15N2, 98%), 0.25 G, 5522-55-4
Cambridge Isotope Laboratories INDOLE-3-ACETIC ACID (PHENYL-13C6, 99%), 0.01 G
INDOLE-3-ACETIC ACID (PHENYL-13C6, 99%), 0.01 G
Cambridge Isotope Laboratories POTASSIUM THIOCYANATE (13C, 95-99%) 95%+ PURE, 0.5 G, 143827-33-2
POTASSIUM THIOCYANATE (13C, 95-99%) 95%+ PURE, 0.5 G, 143827-33-2
Cambridge Isotope Laboratories L-ALANINE (1-13C, 99%), 0.5 G, 21764-56-7
L-ALANINE (1-13C, 99%), 0.5 G, 21764-56-7
Cambridge Isotope Laboratories ETHYL ACETATE (1-13C, 99%), 5 G, 3424-59-7
ETHYL ACETATE (1-13C, 99%), 5 G, 3424-59-7
Medchemexpress LLC Thymidine-15N2 | 50-89-5 | 244.22 | 5 MG
Thymidine-15N2 is the 15N labeled Thymidine, a specific precursor of deoxyribonucleic acid. It is used as a cell synchronizing agent and functions as a DNA synthesis inhibitor, capable of arresting cells at the G1/S boundary prior to DNA replication. Stable heavy isotopes, such as 15N, are incorporated into drug molecules to serve as tracers for quantitation during drug development.
- Used as a tracer and an internal standard for quantitative analysis.
- Can be analyzed by NMR, GC-MS, or LC-MS techniques.
- Functions as a DNA synthesis inhibitor.
- Arrests cells at the G1/S boundary.
- Suitable for metabolic flux analysis.
- Applied in various research areas, including cancer, cell cycle, and anti-infection studies.