Isotopically Labeled Compounds
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Medchemexpress LLC Alfacalcidol-d6 | 1641940-94-4 | C27H38D6O2 | 5 MG
Alfacalcidol-d6 is the deuterium labeled Alfacalcidol, functioning as a non-selective VDR activator. This compound can be utilized as a tracer and an internal standard for quantitative analysis methods such as NMR, GC-MS, or LC-MS.
- Deuterium-labeled compound
- Non-selective VDR activator
- Suitable for use as a tracer
- Functions as an internal standard for quantitative analysis
- Applicable in NMR, GC-MS, and LC-MS analytical techniques
Storage conditions: Powder: -20°C for 3 years, 4°C for 2 years. In solvent: -80°C for 2 years, -20°C for 1 year.
Medchemexpress LLC Arachidic acid-d4 (Icosanoic acid-d4) | 1219803-69-6 | 316.56 | 1 MG
Arachidic acid-d4 is the deuterium-labeled version of Arachidic acid, a long-chain saturated fatty acid also known as Eicosanoic acid. It is naturally found in plasma phospholipids, fish, cannabis, and various plant oils. This compound is valuable as a tracer or an internal standard for quantitative analysis, especially with techniques like NMR, GC-MS, or LC-MS.
- Deuterium-labeled version of arachidic acid.
- Long-chain saturated fatty acid.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis.
- Suitable for NMR, GC-MS, or LC-MS applications.
- Deuteration may affect pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC Creatine-d3 | 143827-19-4 | 99.5% | 134.15 | 25 MG
Creatine-d3 is a deuterium-labeled Creatine. Creatine, an endogenous amino acid derivative, plays an important role in cellular energy, particularly in muscle and brain.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes are incorporated into drug molecules, primarily as tracers for quantitation during drug development.
- Deuteration can affect the pharmacokinetic and metabolic profiles of drugs.
Cayman Chemical Rabeprazole-d4sodIum salt 1mg
An internal standard for the quantification of rabeprazole by GC- or LC-MS
Cayman Chemical ConIvaptn-d4 1mg
An internal standard for the quantification of conivaptan by GC- or LC-MS
New England Biolabs, Inc. Ribonucleoside-Vanadyl Complex (200 mM) – 10 ml
Ribonucleoside-vanadyl complex is a potent inhibitor of various ribonucleases. This complex is compatible with cell fractionation methods as well as sucrose-gradient centrifugations. The 200 mM stock solution is reconstituted to a green-black clear solution by incubating the sealed vial at 65C. Once open, the entire sample should be aliquoted into smaller samples and frozen. The ribonucleoside-vanadyl complex should be added to all buffers to a final concentration of 10 mM. The buffers should not contain EDTA since one equivalent will totally dissociate the complex. We do not recommend the use of the vanadyl complex in cell-free translation systems and with reverse transcriptase). The vanadyl complex can be used in the selective degradation of DNA while preserving RNA since pancreatic deoxyribonuclease I is not inhibited. Removal of the ribonucleoside-vanadyl complex from the RNA can be accomplished by adding 10 equivalents of EDTA before ethanol precipitation.
Medchemexpress LLC Losartan-d4 | 1030937-27-9 | 99.4% | 426.94 | 5 MG
Losartan-d4 is the deuterium labeled Losartan. Losartan is an angiotensin II receptor antagonist, competing with the binding of angiotensin II to AT1 receptors with an IC50 of 20 nM.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Sigma Aldrich Fine Chemicals Biosciences Glycine 2 13C 99 atom 13C1G
REAGENT Glycine 2 13C 99 atom 13C1G
Medchemexpress LLC C18-ceramide-d7 | 1840942-14-4 | 99.0% | 573.00 | C36H64D7NO3 | 500 UG
C18-ceramide-d7 is a deuterium-labeled analogue of C18-ceramide used as a tracer and internal standard in lipid analysis and mass spectrometry. Supplied as a solution at 1.75 mM in methanol:chloroform (10:90), the material is intended for research use only and should be stored at -20°C.
- Isotopically labeled internal standard (d7) for quantitative lipidomics
- High purity: 99.0%
- Molecular weight: 573.00
- Chemical formula: C36H64D7NO3
- Pack size: 500 μg, 1.75 mM in 500 μL
- Storage: store at -20°C
Medchemexpress LLC 1,25-dihydroxyvitamin D3-13C3 (calcitriol-13C3) | 32222-06-3 | 97.0% | 413.57 | C24(13C3)H38O3 | 5 UG
Calcitriol-13C3 is a 13C-labeled form of calcitriol (1,25-dihydroxyvitamin D3) provided as a stable-isotope analytical standard for research use. It is intended as a tracer and internal standard for quantitative NMR, GC-MS, and LC-MS methods and is supplied as a small-volume ethanolic solution; protect from light and store under inert atmosphere for recommended shelf life.
Cayman Chemical 2-NonylquInolIn-4 1H-on-d4 5mg
An internal standard for the quantification of 2-nonylquinolin-4(1H)-one by GC- or LC-MS
Medchemexpress LLC Pregn-4-ene-3,20-dione-1,2-d2, 11,17,21-trihydroxy-, (11β)- | 1257650-73-9 | 364.47 | 5 MG
Hydrocortisone-d2 is a deuterium-labeled version of Hydrocortisone (Cortisol), a naturally occurring steroid hormone and glucocorticoid secreted by the adrenal cortex. This compound is intended for research use only and serves as a valuable tool in scientific studies.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Offers potential to affect pharmacokinetic and metabolic profiles of drugs due to deuteration.
- Used in studies investigating the impact of deuterium substitution on pharmaceutical pharmacokinetics.
- Used in research on the differential effects of hydrocortisone on tight junction proteins and allergic T-cell responses.
- Utilized in studies exploring hydrocortisone's role in preserving the vascular barrier.
Medchemexpress LLC L-Tryptophan-d8 | 1233395-93-1 | 212.27 | 5 MG
L-Tryptophan-d8 is the deuterium labeled L-Tryptophan, an essential amino acid that acts as a precursor of serotonin, melatonin, and vitamin B3.
- Can be used as a tracer.
- Functions as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC L-Asparagine-15N2 monohydrate | 287484-32-6 | 152.12 | 5 MG
L-Asparagine-15N2 monohydrate is the 15N-labeled version of L-Asparagine monohydrate. L-Asparagine monohydrate is an essential amino acid for leukemic cells and serves as a substrate for L-Asparaginase. L-Asparaginase is a potent anti-leukemic enzyme that depletes asparagine (Asn) and glutamine (Gln), thereby inhibiting protein biosynthesis in lymphoblasts. The removal of L-asparagine from plasma by L-Asparaginase leads to inhibition of RNA and DNA synthesis and subsequent apoptosis. L-Asparaginase demonstrates cell-killing ability both in vitro and in vivo, selectively inhibiting the growth of cancer cells that have low asparagine synthetase (AASNS) expression. L-Asparagine monohydrate can also be utilized as a biomarker and sensor for the study of childhood acute lymphoblastic leukemia.
- This compound can be used as a tracer.
- This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.