Isotopically Labeled Compounds
Medchemexpress LLC Glyburide-d3 | 1219803-02-7 | C23H25D3ClN3O5S | 1 MG
Glyburide-d3 is a deuterium-labeled version of Glibenclamide, an orally active inhibitor of ATP-sensitive K+ channels (KATP). It is used in research related to diabetes and obesity, inhibiting P-glycoprotein and blocking SUR1 subunits of KATP. Glyburide-d3 also impacts mitochondrial bioenergetics and can induce autophagy.
- Deuterium labeled version of Glibenclamide.
- Orally active ATP-sensitive K+ channel (KATP) inhibitor.
- Used in research for diabetes and obesity.
- Inhibits P-glycoprotein.
- Blocks SUR1 subunits of KATP.
- Inhibits cystic fibrosis transmembrane conductance regulator protein (CFTR).
- Impacts mitochondrial bioenergetics.
- Can induce autophagy.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Cayman Chemical Prostaglandin D2 methyl ester
PGD2 methyl ester is a more lipid-soluble, cell-permeable prodrug form of PGD2.{14117} It binds to the human and mouse PGD2 receptors (DP1 and CRTH2/DP2) with 5-10 fold lower affinity than PGD2.{11494}
Cambridge Isotope Laboratories p-Coumaric acid (propyl-13C3 99%) CP 99% 1 mg
p-Coumaric acid (propyl-13C3 99%) CP 99% 1 mg
Cayman Chemical -ClImbazole-d4 1mg
An internal standard for the quantification of climbazole by GC- or LC-MS
Cambridge Isotope Laboratories 1 2 3-TriCN (PCN-13) (13C10 99%) 10 ug/mL in isooctane 1 2 mL
1 2 3-TriCN (PCN-13) (13C10 99%) 10 ug/mL in isooctane 1 2 mL
Cayman Chemical -cIs-EpoxIconazole-d4 500ug
An internal standard for the quantification of cis-epoxiconazole by GC- or LC-MS
Medchemexpress LLC Indole-d6 | 104959-27-5 | MFCD22124219 | 123.18 | 5 MG
Indole-d6 is the deuterium labeled Indole, an endogenous metabolite. This compound can be used as a tracer and as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS. Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Cambridge Isotope Laboratories Uridine phosphoramidite (U-15N2 98%) CP 95% 50 mg
Uridine phosphoramidite (U-15N2 98%) CP 95% 50 mg
Medchemexpress LLC Heptadecanoic acid-d3 | 202528-95-8 | 273.47 | 10 MG
Heptadecanoic acid-d3 is the deuterium labeled Heptadecanoic acid. Heptadecanoic acid is an odd chain saturated fatty acid (OCS-FA). It is associated with several diseases, including coronary heart disease, prediabetes, type 2 diabetes, and multiple sclerosis.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Creatine-d3 | 143827-19-4 | 99.5% | 134.15 | 25 MG
Creatine-d3 is a deuterium-labeled Creatine. Creatine, an endogenous amino acid derivative, plays an important role in cellular energy, particularly in muscle and brain.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes are incorporated into drug molecules, primarily as tracers for quantitation during drug development.
- Deuteration can affect the pharmacokinetic and metabolic profiles of drugs.
Cayman Chemical HydrocortIson-d4 1mg
An internal standard for the quantification of hydrocortisone/cortisol by GC- or LC-MS
Cambridge Isotope Laboratories Cytidine phosphoramidite (U-15N3 98%) CP 95% 10 mg
Cytidine phosphoramidite (U-15N3 98%) CP 95% 10 mg
Cambridge Isotope Laboratories O O-Dimethyl thiophosphate potassium salt (dimethyl-D6 98%) 100 ug/mL in methanol 1 2 mL
O O-Dimethyl thiophosphate potassium salt (dimethyl-D6 98%) 100 ug/mL in methanol 1 2 mL