Isotopically Labeled Compounds
Revvity Health Sciences Inc Unquenched standard set (H-3, C-14, blank), 10 mL
Unquenched standard set (H-3, C-14, blank), 10 mL
Selleck Chemical LLC Estrone-d4 E8251-1MG
Estrone-D4 is the deuterated form of Estrone Estrone is an estrogen
Cambridge Isotope Laboratories L-Glutamine-N-Fmoc (13C5 99% 15N2 99%) 0 1 g
L-Glutamine-N-Fmoc (13C5 99% 15N2 99%) 0 1 g
Medchemexpress LLC (Rac)-DPPC-d6 | 82765-17-1 | 98.0% | 740.08 | 10 MG
This product is a deuterated labeled phosphoglyceride used in lipid research.
- Suitable for lipid research applications.
Cambridge Isotope Laboratories SODIUM PYRUVATE (3-13C, 99%), 0.25 G, 124052-04-6
SODIUM PYRUVATE (3-13C, 99%), 0.25 G, 124052-04-6
Medchemexpress LLC Nizatidine-d3 | 1246833-99-7 | 98.8% | 5 MG
Nizatidine-d3 is the deuterium-labeled form of Nizatidine, a potent and orally active histamine H2 receptor antagonist. It is used in the research of stomach and intestinal ulcers by decreasing gastric acid secretion and preventing ulcer recurrence. Its deuterium labeling makes it valuable as a tracer and internal standard for quantitative analysis in drug development.
- Deuterium labeled Nizatidine
- Potent and orally active histamine H2 receptor antagonist
- Used for research of stomach and intestines ulcers
- Decreases secretion of gastric acid
- Prevents ulcers from returning after healing in animal models
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Venlafaxine-d6 | 1020720-02-8 | 98.55% | 5 MG
Venlafaxine-d6 is the deuterium labeled Venlafaxine. Venlafaxine (Wy 45030) is an orally active, potent serotonin (5-HT)/norepinephrine (NE) reuptake dual inhibitor and an antidepressant. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules
Medchemexpress LLC Xylometazoline-d4 hydrochloride | 1218-35-5 | 1 MG
Xylometazoline-d4 hydrochloride is a deuterated form of Xylometazoline hydrochloride (HY-B0475). Xylometazoline hydrochloride acts as an α-adrenergic receptor agonist with a Ki ranging from 0.05 to 1.7 μM. It is known for its ability to constrict nasal blood vessels and consequently increase nasal airflow, making it suitable for research concerning nose stuffiness and runny nose.
- This compound serves as a tracer.
- It can be utilized as an internal standard for quantitative analysis through methods like NMR, GC-MS, or LC-MS.
- Stable heavy isotopes, such as deuterium, are incorporated into drug molecules primarily for quantitation during the drug development process.
- Deuteration can impact the pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC Flumequine-13C3 | 1185049-09-5 | 1 MG
Flumequine-13C3 is the 13C3 labeled Flumequine. It is a quinolone antibiotic that acts as a topoisomerase II inhibitor, with an IC50 of 15 μM (3.92 μg/mL).
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Applicable in isotope-labeled compounds research
- Suitable for metabolic flux analysis
- Used in therapeutic drug monitoring
Medchemexpress LLC Trospium-d8 chloride | 10405-02-4 | 1 MG
Trospium-d8 (chloride) is the deuterium-labeled form of Trospium chloride. Trospium chloride is an orally active, specific, and competitive antagonist of muscarinic cholinergic receptors (mAChRs), exhibiting antimuscarinic activity. It binds with high affinity to muscarinic receptors M1, M2, and M3, but not nicotinic cholinergic receptors.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Incorporation of stable heavy isotopes can affect pharmacokinetic and metabolic profiles of drugs
Medchemexpress LLC 2-Piperidinecarboxamide, N-(2,6-dimethylphenyl)-1-propyl-d7 | 1392208-04-6 | 99.6% | 1 MG
(Rac)-Ropivacaine-d7 is a stable isotope-labeled compound, identified as 2-Piperidinecarboxamide, N-(2,6-dimethylphenyl)-1-propyl-d7. It appears as a white to off-white solid with an isotopic enrichment of 99.11%. This product is intended for research use only and should be handled by qualified personnel in appropriately equipped facilities.
- High purity of 99.6% (HPLC)
- Stable under recommended storage conditions
- Ideal for laboratory chemical applications and substance manufacturing
- For research use only
Medchemexpress LLC 2-Oxazolidinone, 5-[(3,5-dimethylphenoxy-2,4,6-d3)methyl]- | 1192812-66-0 | 98.0% | 5 MG
Metaxalone-d3 is a deuterium-labeled derivative of Metaxalone, an FDA-approved muscle relaxant. It primarily acts on the central nervous system by inhibiting polysynaptic reflex arcs. It also inhibits MAO-A, offering anti-inflammatory and antioxidant effects. Stable heavy isotopes have been incorporated into drug molecules for tracing and can influence drug pharmacokinetics and metabolic profiles.
- Deuterium labeled Metaxalone
- FDA-approved muscle relaxant
- Inhibits polysynaptic reflex arcs
- Inhibits MAO-A, providing anti-inflammatory and antioxidant effects
- Isotopic enrichment of 99.10%
Medchemexpress LLC Moricizine Hydrochloride | 29560-58-5 | 98.0% | 5 MG
Moricizine Hydrochloride (EN 313) is an orally active Class I antiarrhythmic agent. It works by decreasing the maximum rate of phase 0 depolarization, increasing the rates of phase 2 and 3 repolarization, and decreasing both the action potential duration and the effective refractory period.
- Orally active class I antiarrhythmic agent
- Decreases the maximum rate of phase 0 depolarization
- Increases rates of phase 2 and 3 repolarization
- Decreases action potential duration
- Decreases effective refractory period
- Target: Cytochrome P450
- Pathway: Metabolic enzyme/protease
Medchemexpress LLC Rabeprazole-d4 sodium | 117976-90-6 | 98.6% | 1 MG
Rabeprazole-d4 sodium is a deuterium-labeled version of Rabeprazole sodium, a second-generation proton pump inhibitor. It irreversibly inactivates gastric H+/K+-ATPase and induces apoptosis. This compound is suitable for research on gastric ulcerations and gastroesophageal reflux.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Rabeprazole-d4 sodium | 117976-90-6 | 98.6% | 5 MG
Rabeprazole-d4 (sodium) is the deuterium labeled Rabeprazole sodium, a second-generation proton pump inhibitor (PPI) that irreversibly inactivates gastric H+/K+-ATPase. It induces apoptosis and acts as a uridine nucleoside ribohydrolase (UNH) inhibitor with an IC50 of 0.3 μM. This compound can be used for the research of gastric ulcerations and gastroesophageal reflux.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Incorporates stable heavy isotopes, potentially affecting pharmacokinetic and metabolic profiles of drugs.