Isotopically Labeled Compounds
Medchemexpress LLC Metolazone-d7 | 2714484-71-4 | 99.9% | 5 MG
Metolazone-d7 is deuterium-labeled Metolazone, primarily used to treat congestive heart failure and high blood pressure. Stable heavy isotopes have been incorporated into this drug molecule for use as tracers in drug development, with deuteration potentially affecting pharmacokinetic and metabolic profiles.
- Molecular weight: 372.88
- Formula: C16H9D7ClN3O3S
- Unlabeled CAS: 17560-51-9
- Appearance: Solid
- Color: White to off-white
- Shipped at room temperature (continental US)
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Solubility in DMSO: ≥ 100 mg/mL
- Solubility in H2O: 0.67 mg/mL (requires ultrasonic)
- Storage (powder): -20°C for 3 years, 4°C for 2 years
- Storage (in solvent): -80°C for 6 months, -20°C for 1 month
Medchemexpress LLC Metolazone-d7 | 2714484-71-4 | 99.90% | 1 MG
Metolazone-d7 is deuterium labeled Metolazone, primarily used to treat congestive heart failure and high blood pressure. This compound can be used as a tracer and as an internal standard for quantitative analysis. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Used as a tracer
- Functions as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Deuterium substitution impacts pharmacokinetics
Medchemexpress LLC Metolazone-d7 | 2714484-71-4 | 99.9% | 500 UG
Metolazone-d7 is deuterium labeled Metolazone, primarily used to treat congestive heart failure and high blood pressure. Deuteration, the incorporation of stable heavy isotopes into drug molecules, has gained attention for its potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Cambridge Isotope Laboratories SODIUM PYRUVATE (1-13C, 99%), 0.5 G, 87976-71-4
SODIUM PYRUVATE (1-13C, 99%), 0.5 G, 87976-71-4
Cambridge Isotope Laboratories SODIUM PYRUVATE (1-13C, 99%), 1 G, 87976-71-4
SODIUM PYRUVATE (1-13C, 99%), 1 G, 87976-71-4
Apexbio Technology LLC Nortriptyline (hydrochloride) 894-71-3 10mM (in 1mL DMSO)
Nortriptyline hydrochloride (CAS 894-71-3) is a dibenzocycloheptene-derived tricyclic antidepressant that inhibits monoamine reuptake transporters It selectively blocks the norepinephrine transporter (NET) with a Ki of 3 4 nM and inhibits the serotonin transporter (SERT) with a Ki of 161 nM thereby increasing synaptic concentrations of these neurotransmitters in the central nervous system In vitro nortriptyline dose-dependently suppresses spontaneous migration and chemotaxis of human polymorphonuclear cells In vivo studies in rodents indicate partial blockade of noradrenaline depletion in nerve terminals at higher doses Nortriptyline is frequently employed in research on monoaminergic neurotransmission and antidepressant pharmacology
Apexbio Technology LLC Nortriptyline (hydrochloride) 894-71-3 100mg
Nortriptyline hydrochloride (CAS 894-71-3) is a dibenzocycloheptene-derived tricyclic antidepressant that inhibits monoamine reuptake transporters It selectively blocks the norepinephrine transporter (NET) with a Ki of 3 4 nM and inhibits the serotonin transporter (SERT) with a Ki of 161 nM thereby increasing synaptic concentrations of these neurotransmitters in the central nervous system In vitro nortriptyline dose-dependently suppresses spontaneous migration and chemotaxis of human polymorphonuclear cells In vivo studies in rodents indicate partial blockade of noradrenaline depletion in nerve terminals at higher doses Nortriptyline is frequently employed in research on monoaminergic neurotransmission and antidepressant pharmacology
Apexbio Technology LLC Nortriptyline (hydrochloride) 894-71-3 50mg
Nortriptyline hydrochloride (CAS 894-71-3) is a dibenzocycloheptene-derived tricyclic antidepressant that inhibits monoamine reuptake transporters It selectively blocks the norepinephrine transporter (NET) with a Ki of 3 4 nM and inhibits the serotonin transporter (SERT) with a Ki of 161 nM thereby increasing synaptic concentrations of these neurotransmitters in the central nervous system In vitro nortriptyline dose-dependently suppresses spontaneous migration and chemotaxis of human polymorphonuclear cells In vivo studies in rodents indicate partial blockade of noradrenaline depletion in nerve terminals at higher doses Nortriptyline is frequently employed in research on monoaminergic neurotransmission and antidepressant pharmacology