Molecular Sieves
Apexbio Technology LLC TCS-PIM-1-4a 327033-36-3 5mg
TCS-PIM-1-4a is a small-molecule inhibitor targeting Pim kinases a family of serine/threonine kinases It is designed to selectively inhibit Pim kinases thereby modulating signaling pathways related to cell growth and survival TCS-PIM-1-4a exerts its biological activity primarily through activation of AMP-activated protein kinase (AMPK) resulting in inhibition of the mammalian target of rapamycin complex 1 (mTORC1) signaling pathway In cell-based studies TCS-PIM-1-4a demonstrates cytotoxic activity against diverse hematological tumor cell lines including myeloid and lymphoid subtypes with IC50 values ranging from approximately 0 8 to 40 M Based on these pharmacological properties TCS-PIM-1-4a holds research potential in investigations of Pim kinase signaling and therapeutic strategies for hematological malignancies
Strem, An Ascensus Company CAS# 70955-01-0. 1kg. Molecular sieves, -600 mesh powder (Linde 4A). MFCD00131613
CAS# 70955-01-0. 1kg. Molecular sieves, -600 mesh powder (Linde 4A). MFCD00131613. Molecular Weight: . Molecular Formula: . Color/form: white pwdr. Strem# 93-5403. http://www.strem.com/catalog/v/93-5403/
Cayman Chemical 15hydroxy ProstaglndIn Dehy
Cayman’s 15-PGDH Inhibitor Screening Assay Kit provides a robust and EAsy-to-use platform for identifying novel inhibitors of human 15-PGDH, the enzyme that catalyzes the oxidation of prostaglandins to 15-keto metabolites with reduced biological activity. Measurement of 15-PGDH activity is carried out by monitoring the reduction of NAD+ to NADH. The reduction of NAD+ to NADH is accompanied by an increase in fluorescence at 445 nm following excitation at 340 nm. The potent and reversible 15-PGDH inhibitor ML-148 Assay Reagent is included as a positive control and inhibits 15-PGDH with an IC50 value of 11 nM.
Medchemexpress LLC Nutlin-3a | 675576-98-4 | MFCD14636430 | 99.1% | 581.49 | C30H30Cl2N4O4 | 25 MG
Nutlin-3a is a small-molecule MDM2 antagonist used in research to activate wild-type p53, stabilize p53 protein, and induce apoptosis and autophagy. It is intended for laboratory research use and is characterized for cell-based and biochemical assays.
- Inhibits MDM2-p53 interaction, leading to p53 activation.
- Induces apoptosis and autophagy in p53 wild-type cells.
- High reported purity (≈99.1%) suitable for research applications.
- Molecular formula C30H30Cl2N4O4 and molecular weight ~581.5 g/mol.
- Available in multiple solid and solution sizes for experimental flexibility.
- For research use only; not for human or animal therapeutic use.
Medchemexpress LLC Avg-233 | 2151937-80-1 | 98.1% | 25 MG
AVG-233 (CAS 2151937-80-1) is a small-molecule RNA-dependent RNA polymerase (RdRp) inhibitor used for research on respiratory syncytial virus (RSV). It prevents initiation of the viral polymerase complex and shows nanomolar activity against RSV isolates (reported EC50 = 0.14-0.31 μM). Supplied as an off-white to yellow solid for laboratory use.
- Potent RdRp inhibitory activity (RSV EC50 = 0.14-0.31 μM).
- High purity solid, typically reported around 98%.
- Molecular formula C26H22ClN5O3; molecular weight 487.94.
- Available in multiple small-scale pack sizes suitable for research.
- Intended for in vitro and preclinical research; follow safety and storage recommendations.
Medchemexpress LLC Semaphorin-4A/SEMA4A 50ug
Recombinant mouse Semaphorin-4A extracellular domain expressed in HEK293 cells, supplied lyophilized with a C-terminal 6xHis tag. Provided at 50 μg with >95% purity and formulated for stability; certificate of analysis and datasheet are available for quality verification.
- Mouse extracellular domain (residues T33-H682).
- Expressed in HEK293 mammalian cells for proper folding and post-translational modifications.
- C-terminal 6xHis tag for affinity purification and detection.
- Lyophilized formulation with stabilizers for extended storage stability.
- Purity greater than 95% as determined by reducing SDS-PAGE.
- Supplied at 50 μg suitable for in vitro research applications.
- Certificate of analysis and datasheet provided for quality assurance.
Cayman Chemical 15-hydroxy Prostaglandin Dehy
Immunogen: Synthetic peptide from an internal region of human 15-PGDH • Host: Rabbit • Species Reactivity: (+) Human, baboon, mouse • Application: WB
Sigma Aldrich Fine Chemicals Biosciences Molecular sieves 5 A 3.21KG
REAGENT Molecular sieves 5 A… 3.21KG
Medchemexpress LLC (Z)-1-((2-(trifluoromethyl)phenyl)methylene)-5-(thiazol-2-yl)thiourea | 438190-29-5 | MFCD01152003 | 99.9% | 273.23 g·mol⁻¹ | C11H6F3NO2S | 10 MG
SMI-4a is a selective, cell-permeable, ATP-competitive inhibitor of Pim-1 kinase supplied as a high-purity research chemical. It inhibits Pim-1 (IC50 = 24 μM; Ki = 0.6 μM) and Pim-2 (IC50 = 100 μM), is provided as a white to off-white solid in a 10 mg package, and includes recommended storage conditions for powder and solutions.
- Selective ATP-competitive Pim-1 kinase inhibitor suitable for research use.
- High purity suitable for biochemical and cellular assays.
- Supplied as a 10 mg solid for small-scale experiments.
- Includes storage recommendations for powder and dissolved samples.
- Contains chemical identifiers for unambiguous compound tracking.
Chem-Impex International, Inc. Molecular sieves, 3?, beads 8-12 mesh | 1318-02-1 | MFCD00147627 | 1KG
Molecular sieves, 3?, beads 8-12 mesh, 1318-02-1, MFCD00147627, 1KG
Sigma Aldrich Fine Chemicals Biosciences Molecular sieves, 4 Ã… pellets, 1.6 mm diameter | 70955-01-0 | MFCD00131613 | 1KG
Molecular sieves, 4 Ã… pellets, 1.6 mm diameter | 70955-01-0 | MFCD00131613 | 1KG
Cayman Chemical 15hydroxy ProstaglndIn Dehy
Source: Active recombinant human C-terminal His-tagged 15-PGDH expressed in E. coli • Amino acids: 3-256 • MW: 29.9 kDa
Medchemexpress LLC 4alpha-phorbol 12-myristate 13-acetate | 63597-44-4 | MFCD00153860 | 99.0% | 616.83 | C36H56O8 | 1 MG
4alpha-phorbol 12-myristate 13-acetate is the inactive stereoisomer of TPA used as a negative control in experiments that monitor TPA-activated signaling events. It is supplied as a high-purity research reagent in a small-mass vial suitable for in vitro assays.
- Inactive negative control for TPA-activated events.
- High purity (99.0%) for reproducible results.
- Molecular formula C36H56O8 and molecular weight 616.83 for accurate identification.
- Supplied in a 1 mg package suitable for small-scale studies.
Medchemexpress LLC Semaphorin-3A (SEMA3A) protein, mouse, Fc-tag | >95.0% | 500 UG
Recombinant mouse Semaphorin-3A (SEMA3A) is supplied as an N-terminal human Fc-tagged protein expressed in HEK293 cells for in vitro research. The protein is glycosylated, with an apparent molecular weight of approximately 80-95 kDa, and is available in sizes up to 500 μg.
- Purity greater than 95% by reducing SDS-PAGE.
- N-terminal human Fc tag facilitates detection and capture.
- Expressed in HEK293 to preserve mammalian glycosylation.
- Glycosylated molecular weight approximately 80-95 kDa.
- Store at -20°C; aliquot and freeze at -80°C for long-term storage.