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SMI-4a is a selective, cell-permeable, ATP-competitive inhibitor of Pim-1 kinase supplied as a high-purity research chemical. It inhibits Pim-1 (IC50 = 24 μM; Ki = 0.6 μM) and Pim-2 (IC50 = 100 μM), is provided as a white to off-white solid in a 10 mg package, and includes recommended storage conditions for powder and solutions.
Selective ATP-competitive Pim-1 kinase inhibitor suitable for research use.
High purity suitable for biochemical and cellular assays.
Supplied as a 10 mg solid for small-scale experiments.
Includes storage recommendations for powder and dissolved samples.
Contains chemical identifiers for unambiguous compound tracking.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
Nutlin-3a is a research-grade small-molecule MDM2 antagonist that stabilizes and activates p53, promoting apoptosis and autophagy in preclinical studies. Supplied as a purified solid for laboratory use, it is intended for cellular and biochemical investigation of p53-dependent pathways.
Potent MDM2 inhibitor that activates p53 signaling.
High purity suitable for research applications.
Characterized molecular weight and formula for analytical work.
Available in small quantities for experimental testing.
Documented in literature for studies of apoptosis and autophagy.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
A cholane-scaffold small molecule that functions as a selective agonist of GPBAR1 (TGR5) and is used in research on FXR and bile-acid receptor-mediated signaling. Supplied in solution and solid formats for flexibility in assay setup, it is intended for in vitro pharmacology and signaling studies.
High purity suitable for biochemical and cell-based assays.
Available as a 10 mM solution in DMSO for immediate use in assays.
Also offered as solid material in multiple sizes for dose optimization.
Molecular formula and weight provided to support analytical planning.
Commonly used in studies of bile acid receptor signaling and metabolic disease models.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
AVG-233 is a potent, orally active RNA-dependent RNA polymerase (RdRp) inhibitor used for research into respiratory syncytial virus (RSV). It prevents initiation of the viral polymerase complex and shows nanomolar activity against RSV strains and clinical isolates.
Potent RNA-dependent RNA polymerase inhibitor.
Reported EC50 = 0.14-0.31 μM against RSV strains and clinical isolates.
Molecular formula: C26H22ClN5O3.
Molecular weight: 487.94 g/mol.
Available as a solid in multiple pack sizes (5 mg-500 mg).
Intended for research use only; not for human or diagnostic use.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Molecular sieves are crystalline metal aluminosilicates having a 3-dimensional interconnecting network of silica and alumina tetrahedra. Natural water of hydration is removed from this network by heating to produce uniform cavities which selectively adsorb molecules of a specific size. The 3A form is made by substituting potassium cations for the inherent sodium ions of the 4A structure reducing the effective pore size to ~3A… excluding diameter 3A… e.g. ethane. The 4 to 8-mesh type is normally used in gas-phase applications. Molecular sieves are considered a universal drying agent in polar and nonpolar media.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More