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Molecular sieves are materials with pores of uniform size and diameter that are similar in size to small molecules; used to separate molecules by size; available in various pore size ranges, with drying solvent indicators, etc.
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Recombinant human Semaphorin-4A Fc fusion protein produced in HEK293 cells and supplied as a sterile, 0.22 μm filtered PBS solution (pH 7.4). The product is provided with analytical data confirming biological activity, an endotoxin specification, and a certificate of analysis reporting high purity. Intended for biochemical and cell-based assays involving SEMA4A interactions and signaling.
Expressed in HEK293 cells as an Fc fusion.
Supplied as PBS buffer, pH 7.4, 0.22 μm filtered.
Endotoxin level <1 EU/μg.
Purity 93.0% as determined by reducing SDS-PAGE.
Suitable for biochemical and cell-based interaction assays.
Store at -80°C and avoid repeated freeze-thaw cycles.
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4alpha-phorbol 12-myristate 13-acetate is the inactive stereoisomer of TPA used as a negative control in experiments that monitor TPA-activated signaling events. It is supplied as a high-purity research reagent in a small-mass vial suitable for in vitro assays.
Inactive negative control for TPA-activated events.
High purity (99.0%) for reproducible results.
Molecular formula C36H56O8 and molecular weight 616.83 for accurate identification.
Supplied in a 1 mg package suitable for small-scale studies.
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Regeneration or ActivationA saturated molecular sieve can be restored to its original capacity by regeneration the principle of which involves changing the conditions surrounding the adsorbent to correspond to a very low equilibrium capacity. In general the greater the difference between the equilibrium capacities of adsorption and regeneration the more rapid and complete the regeneration.The sieve may be regenerated in one of four ways1. Thermal reactivation -The maximum regeneration temperature for Silica is 300C.2. Pressure reactivation3. Passing an appropriate fluid through the gel bed at normal temperature and pressure.4. Displacement of adsorbates by passing a high concentration of molecules in a fluid through the bed.
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Regeneration or ActivationA saturated molecular sieve can be restored to its original capacity by regeneration the principle of which involves changing the conditions surrounding the adsorbent to correspond to a very low equilibrium capacity. In general the greater the difference between the equilibrium capacities of adsorption and regeneration the more rapid and complete the regeneration.The sieve may be regenerated in one of four ways1. Thermal reactivation -The maximum regeneration temperature for Silica is 300C.2. Pressure reactivation3. Passing an appropriate fluid through the gel bed at normal temperature and pressure.4. Displacement of adsorbates by passing a high concentration of molecules in a fluid through the bed.
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Cayman’s 15-PGDH Inhibitor Screening Assay Kit provides a robust and easy-to-use platform for identifying novel inhibitors of human 15-PGDH, the enzyme that catalyzes the oxidation of prostaglandins to 15-keto metabolites with reduced biological activity. Measurement of 15-PGDH activity is carried out by monitoring the reduction of NAD+ to NADH. The reduction of NAD+ to NADH is accompanied by an increase in fluorescence at 445 nm following excitation at 340 nm. The potent and reversible 15-PGDH inhibitor ML-148 Assay Reagent is included as a positive control and inhibits 15-PGDH with an IC50 value of 11 nM.
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Nutlin-3a is a small-molecule MDM2 antagonist used in research to activate wild-type p53, stabilize p53 protein, and induce apoptosis and autophagy. It is intended for laboratory research use and is characterized for cell-based and biochemical assays.
Inhibits MDM2-p53 interaction, leading to p53 activation.
Induces apoptosis and autophagy in p53 wild-type cells.
High reported purity (≈99.1%) suitable for research applications.
Molecular formula C30H30Cl2N4O4 and molecular weight ~581.5 g/mol.
Available in multiple solid and solution sizes for experimental flexibility.
For research use only; not for human or animal therapeutic use.
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