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A collection of genes utilized by the RNA interference (RNAi) pathway; the RNAi pathway is a biological process in which RNA molecules inhibit gene expression or translation by neutralizing targeted mRNA molecules. Ideal for genetic screening.
These siRNA collections enable medium and high throughput analysis of phenotypes resulting from inhibition of large sets of targets from specific functional classes.
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The Silencer™ Select Human Epigenetics siRNA Library contains 1563 Ambion™ Silencer Select highly potent, chemically-modified siRNAs targeting 521 epigenetic enzymes, including those mediating epigenetic signaling through the acetylation and methylation of histones.
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DNA surveillance proteins monitor DNA integrity, and they can activate cell cycle checkpoints and DNA repair pathways in response to DNA damage. This can prevent potentially deleterious mutations.
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The Silencer™ Human Membrane Trafficking siRNA Library is designed for researchers targeting proteins known or predicted to participate in membrane trafficking or remodeling.
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The Invitrogen™ LentiArray™ Human Protease Library targets 475 genes with up to 4 gRNA per gene target (pooled in a single well) for a total of 1,900 gRNAs. Libraries are delivered as 100 μL of ready to use lentiviral particles per gene target.
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