Antibody-Binding Proteins and Conjugates
Revvity Health Sciences Inc AlphaScreen Anti-FITC Donor Beads, 1 mg
AlphaScreen Anti-FITC Donor Beads, 1 mg
Cayman Chemical SalcaprozatesodIum salt 500mg
An intestinal permeation enhancer; increases jejunal accumulation of the bioactive peptide PW5 in vitro in a non-everted rat gut sac model; increases plasma concentrations of orally administered human parathyroid hormone (1-34) in pigs
Biotium CD106 / VCAM1(1.4C3), CF488A conjugate, 0.1mg/mL
CD106 (also known as vascular cell adhesion molecule-1, or VCAM-1) is a member of the Ig superfamily of adhesion molecules. It is expressed at high levels on cytokine stimulated vascular endothelial cells, and at minimal levels on un-stimulated endothelial cells. It is also present on follicular and inter-follicular dendritic cells of lymph nodes, myoblasts, and some macrophages. CD106 serves as a ligand for leukocyte beta-1 integrin VLA-4 and mediates cell adhesion of leukocytes to activated endothelium. It plays a role in various immunological and inflammatory responses.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Biotium Insulin(2D11-H5), CF488A conjugate, 0.1mg/mL
Recognizes a polypeptide which is identified as insulin, a 51-amino acid polypeptide composed of A and B chains connected through the C-peptide. Proinsulin, which has very little biological activity, is cleaved by proteases within its cell of origin into the insulin molecule and the C-terminal basic residue. Insulin enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides, and synthesis of proteins and nucleic acids. Deficiency of insulin results in diabetes mellitus. The main storage site for insulin is the pancreatic islets. Antibodies to insulin are important as beta-cell and insulinoma marker.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have
Biotium Thyroglobulin(2H11), CF488A conjugate, 0.1mg/mL
MAb 2H11 reacts with a partially defined epitope of human thyroglobulin. This epitope is different form the epitope recognized by MAb 6E1. Thyroglobulin is a 660 kDa dimeric pre-protein with mutiple glycosylation sites. It is produced by and processed within the thyroid gland to produce the hormone thyroxine and triiodothyronine. Prior to forming dimers, thyroglobulin monomers undergo conformational maturation in the endoplasmic reticulation. The vast majority of follicular carcinomas of the thyroid will give positive immunoreactivity for anti-thyroglobulin even though sometimes only focally. Poorly differentiated carcinomas of the thyroid are frequently anti-thyroglobulin negative. Adenocarcinomas of other-than-thyroid origin do not react with this antibody. This antibody is useful in identification of thyroid carcinoma of the papillary and follicular types. Presence of thyroglobulin in metastatic lesions establishes the thyroid origin of tumor. Anti-thyroglobulin, combined
Cayman Chemical TInptInsodIum salt 500mg
An atypical antidepressant; an agonist of MORs (EC50s = 194 and 641 nM for human and mouse receptors in a BRET assay for G protein activation; decreases immobility in the forced swim test in wild-type, but not MOR knockout mice at 30 mg/kg; increases locomotor activity at a dose of 30, but not 10 mg/kg, in the open field test; prevents increases in chronic restraint stress-induced GLT-1 expression in the rat hippocampal CA3 region at 10 mg/kg per day for 21 days
Jackson Immuno Research Labs DyLight 405-IgG Fraction Monoclonal Mouse Anti-Fluorescein (FITC)
DyLight 405-IgG Fraction Monoclonal Mouse Anti-Fluorescein (FITC)
Cayman Chemical AzlocIlInsodIum salt 500mg
A semisynthetic with broad spectrum antibacterial properties; used as part of antibiotic cocktails known as PANTA (with polymyxin B, amphotericin B, nalidixic acid, and trimethoprim) and PANTAV (PANTA with vancomycin)
Cayman Chemical MItIglInIdecalcIum salt 500mg
A SUR1/Kir6.2 inhibitor (IC50 = 4 nM); selective for SUR1/Kir6.2 over SUR2A/Kir6.2 and SUR2B/Kir6.2 channels (IC50s = 3 and 5 µM, respectively); induces insulin release in HIT-T15 insulinoma cells and isolated mouse pancreatic islets at 100 µM; increases postprandial plasma insulin levels and inhibits postprandial increases in plasma glucose levels in an STZ-induced rat model of diabetes
Biotium Cytokeratin 8(C-43), Biotin conjugate, 0.1mg/mL
Cytokeratin 8 (CK8) belongs to the type II (or B or basic) subfamily of high molecular weight cytokeratins and exists in combination with cytokeratin 18 (CK18). CK8 is primarily found in the non-squamous epithelia and is present in majority of adenocarcinomas and ductal carcinomas. It is absent in squamous cell carcinomas. Hepatocellular carcinomas are defined by the use of antibodies that recognize only cytokeratin 8 and 18. CK8 exists on several types of normal and neoplastic epithelia, including many ductal and glandular epithelia such as colon, stomach, small intestine, trachea, and esophagus as well as in transitional epithelium. Anti-CK8 does not react with skeletal muscle or nerve cells. Epithelioid sarcoma, chordoma, and adamantinoma show strong positivity corresponding to that of simple epithelia (with antibodies against CK8, CK18 and CK19). Reportedly, anti-CK8 is useful for the differentiation of lobular (ring-like, perinuclear) from ductal (peripheral-predominant)
Jackson Immuno Research Labs Alexa Fluor 790-ChromPure Mouse IgG whole molecule
Alexa Fluor 790-ChromPure Mouse IgG whole molecule
Jackson Immuno Research Labs DyLight 405-ChromPure Sheep IgG whole molecule
DyLight 405-ChromPure Sheep IgG whole molecule
Jackson Immuno Research Labs Peroxidase-ChromPure Mouse IgG whole molecule
Peroxidase-ChromPure Mouse IgG whole molecule
Jackson Immuno Research Labs Peroxidase-ChromPure Mouse IgG F(ab')2 fragment
Peroxidase-ChromPure Mouse IgG F(ab')2 fragment