Antibody-Binding Proteins and Conjugates
Revvity Health Sciences Inc AlphaScreen Anti-FITC Donor Beads, 1 mg
AlphaScreen Anti-FITC Donor Beads, 1 mg
Revvity Health Sciences Inc LANCE Ultra Anti-Human IgG ULight Antibody, 2 nmoles
LANCE Ultra Anti-Human IgG ULight Antibody, 2 nmoles
Cayman Chemical Rosiglitazone (potassium salt), Purity: ≥98%, CAS: 316371-84-3, 50 mg
A PPARγ agonist; activates PPARγ1 and PPARγ2 in reporter assays (EC50s = 30 and 100 nM, respectively); selectively activates chimeras containing the LBDs of PPARγ over PPARα and PPARδ in a cell-based reporter assay at 10 mM; an inhibitor of ACSL4 (IC50 = 0.5 µM), inhibits RSL3-induced ferroptosis in Pfa1 cells and Pparg KO cells, and increases survival in a Gpx4 KO mouse model of ferroptosis at 0.0125 mg/ml in the drinking water; decreases HbA1c and fasting blood glucose levels in a rat model of type 2 diabetes induced by STZ and a high-carbohydrate and high-fat diet at 4 mg/kg
Cayman Chemical Angeli's Salt, Purity: ≥99%, CAS: 13826-64-7, 50 mg
A classical nitroxyl (NO-) donor; dissociates in a pH-dependent, first order process with a half-life of 2.3 minutes at 37°C, pH 7.4, to liberate 0.54 moles for NO per mole of parent compound
Biotium CD282 / TLR2(TLR2/221), CF594 conjugate, 0.1mg/mL
This MAb reacts with human Toll-like receptor 2 (TLR2). It is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is expressed most abundantly in peripheral blood leukocytes, and mediates host response to Gram-positive bacteria and yeast via stimulation of NF-kappaB.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low
Biotium HCG-intact(HCGab/52), CF488A conjugate, 0.1mg/mL
This MAb is a very special because it reacts ONLY with the intact-HCG and not with either free alpha- or free beta-chain of HCG. HCG is a glycoprotein and is composed of two non-identical, non-covalently linked polypeptide chains designated as the alpha and beta subunits. The alpha subunit is identical to that of thyroid stimulating hormone (TSH), follicle stimulating hormone (FSH), and luteinizing hormone (LH). HCG is secreted in large quantities by normal trophoblasts. It is present only in trace amounts in non-pregnant urine and sera but rises sharply during pregnancy. HCG MAb detects cells and tumors of trophoblastic origin such as choriocarcinoma. Large cell carcinoma and adenocarcinoma of the lung demonstrate anti-hCG positivity in 90% and 60% of cases respectively. 20% of lung squamous cell carcinomas are positive. HCG expression by non-trophoblastic tumors may indicate aggressive behavior.Primary antibodies are available purified, or with a selection of fluorescent CF
Biotium CD284 / TLR4(TLR4/230), CF647 conjugate, 0.1mg/mL
This MAb reacts with human Toll-like receptor 2 (TLR4). It is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. Mutations in this gene have been associated with differences in LPS responsiveness. Multiple transcript variants encoding different isoforms have been found for this gene.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional
Revvity Health Sciences Inc LANCE Ultra Phospho-BTK (Tyr223) Detection Kit, 10,000 Assay Points
LANCE Ultra Phospho-BTK (Tyr223) Detection Kit, 10,000 Assay Points
Cell Signaling Technology TCF1/TCF7 Monoclonal Antibody, Rabbit, BSA and Azide Free, 100 μg
This TCF1/TCF7 (C63D9) Rabbit Monoclonal Antibody is a carrier-free formulation designed to detect endogenous levels of total TCF1/TCF7 protein. Produced by immunizing animals with a synthetic peptide corresponding to a region surrounding Pro96 of the human TCF1/TCF7 protein, this antibody does not recognize dominant negative isoforms lacking the amino-terminal β-catenin binding domain and does not cross-react with LEF1. This antibody is ideal for specialized or custom labeling applications.
- Validated for western blotting, immunohistochemistry (paraffin), immunofluorescence (frozen and immunocytochemistry), and flow cytometry (fixed/permeabilized)
- Supplied in 1X PBS without BSA or sodium azide
- Quality control tested by size exclusion chromatography
- Reactivity with human and mouse samples
- Recommended to store at -20°C in single-use aliquots
Advanced Targeting Systems 100UG FAB-ZAP HUMAN SECND CONJ
Fab-ZAP is a chemical conjugate of goat anti-human monovalent antibody and the ribosome-inactivating protein, saporin.
Cayman Chemical Semaglutide (sodium salt), Purity: ≥98%, CAS: 2924330-56-1, 50 mg
A GLP-1R agonist (EC50 = 6.2 pM in a reporter assay using BHK cells expressing the human receptor); decreases blood glucose levels in the db/db mouse model of type 2 diabetes (ED50 = <2 nmol/kg); prevents decreases in the number of dopaminergic neurons in the substantia nigra and increases in lipid peroxidation in the substantia nigra and striatum, as well as improves motor coordination in the rotarod and footprint tests in a mouse model of Parkinson’s disease induced by MPTP at 25 nmol/kg; decreases neuronal loss in the hippocampal dentate gyrus and CA1 and CA3 regions and improves motor coordination and grip strength in the beam-walking and hanging wire tests, respectively, in a rat model of stroke induced by permanent MCAO at 10 nmol/kg every other day
Abcam Glutathione Peroxidase Assay Kit (Colorimetric)
Glutathione Peroxidase Assay Kit (Colorimetric)
The product is subject to the following: Abcam Restricted Use Statement
