Flow Cytometry Analyzer Supplies
AdipoGen VSTM5 msFc ms non-lytic
Recombinant protein. The extracellular domain of mouse VSTM5 aa 28-146 is fused to the N-terminus of the mouse Fc IgG2a non-lytic mutant. Source CHO cells. Lyophilized. Contains PBS. The V-set and transmembrane domain-containing protein VSTM family is composed of 8 proteins VSTM1v1, VSTM1v2, VSTM2a, VSTM2b, VSTM2L, VSTM3, VSTM4 and VSTM 5. Members of the VSTM family are associated with the regulation of functions of immune cells, adipose cells and neuronal cells. The VSTM family is an immunoglobulin Ig superfamily that shares structural similarities with the B7-like transmembrane proteins involved in immune regulation. VSTM1 and VSTM4 play positive and negative roles in macrophage activation, respectively. VSTM3 TIGIT acts as a co-inhibitory receptor that suppresses the cytokine production of T cells and NK cells.
AdipoGen IL-2 hSwitch-2monome-KIH
Recombinant protein. The extracellular domain of human IL-2 aa 21-153 mutant pH-resistant Switch-2 containing mutations T37H, R38L, T41S, F42Y, and K43G is fused at the C-terminus to the Fc portion of human IgG1 Knobs-into-Holes technology see reference J.B. Ridgway, et al. Protein Eng. 9, 617 1996. Source HEK 293 cells. Lyophilized. Contains PBS. Interleukin-2 IL-2 is a 133 amino acid glycoprotein with one intramolecular disulfide bond and variable glycosylation. It is secreted by activated T cells and induces proliferation and maturation of activated T cells, natural killer cells and lymphokine activated killer cells. IL-2 also stimulates proliferation of antibody-producing B cells, activates neutrophils and induces mononuclear cells to secrete IFN-gamma and TNF-alpha and -beta.
AdipoGen IL-2 SuperkH9T MonoFc-KIHh
Recombinant Protein. The extracellular domain of human IL-2 aa 21-153 mutant H9T containing the mutations of H9 L80F / R81D / L85V / I 86V / I92F and the new mutation Q126T is fused at the C-terminus to the Fc portion of human IgG1 Knobs-into-Holes technology see reference J.B. Ridgway, et al. Protein Eng. 9, 617 1996. Source HEK 293 cells. Lyophilized. Contains PBS. Interleukin-2 IL-2 is a 133 amino acid glycoprotein with one intramolecular disulfide bond and variable glycosylation. It is secreted by activated T cells and induces proliferation and maturation of activated T cells, natural killer cells and lymphokine activated killer cells. IL-2 also stimulates proliferation of antibody-producing B cells, activates neutrophils and induces mononuclear cells to secrete IFN-gamma and TNF-alpha and -beta.
AdipoGen IL-2 Superk MonomFc-KIHh
Recombinant Protein. Human IL-2 aa 21-153 mutant H9 containing the mutations L80F / R81D / L85V / I 86V / I92F is fused at the C-terminus to the Fc portion of human IgG1 Knobs-into-Holes technology see reference J.B. Ridgway, et al. Protein Eng. 9, 617 1996. Source HEK 293 cells. Lyophilized. Contains PBS. Interleukin-2 IL-2 is a 133 amino acid glycoprotein with one intramolecular disulfide bond and variable glycosylation. It is secreted by activated T cells and induces proliferation and maturation of activated T cells, natural killer cells and lymphokine activated killer cells. IL-2 also stimulates proliferation of antibody-producing B cells, activates neutrophils and induces mononuclear cells to secrete IFN-gamma and TNF-alpha and -beta. Moreover, studies have shown that IL-2 is required for activation-induced apoptosis, an important homeostatic mechanism in the immune system, which is involved in the maintenance of peripheral tolerance to self-antigens.
AdipoGen IL-38 aa20-152hmonom-KIH
Recombinant Protein. Human IL-38 aa 20-152 is fused at the C-terminus to the Fc portion of human IgG1 Knobs-into-Holes technology see reference J.B. Ridgway, et al. Protein Eng. 9, 617 1996. Source HEK 293 cells. Lyophilized. Contains PBS. IL-38 IL-1F10 belongs to the IL-1 family of proteins. IL-38 is expressed in heart, placenta, fetal liver, spleen, thymus and tonsil. The expression in a variety of immune tissues and similarity to IL-1Ra suggest a role of IL-38 in the inflammatory response. It has been reported that removal of the N-terminus domain of the interleukins of the IL-1F family such as IL-1F5 / 6 / 8 or 9 also called IL-36Ra, IL-36alpha, IL-36beta or IL-36gamma is important to increase their biological activity. Recently it has been shown that IL-38 is N-terminally processed and secreted by apoptotic cells.
Biolegend Ultra-LEAFTM Purified anti-hum
Ultra-LEAF™ Purified anti-human CD27 [W22076F]; Isotype: Rat IgG2a, κ; Reactivity: Human; Apps: Block; Size: 100 μg
Biolegend Spark YGTM 593 anti-human CD19
Spark YG™ 593 anti-human CD19 [SJ25C1]; Isotype: Mouse IgG1, κ; Reactivity: Human; Apps: FC; Size: 25 tests
STEMCELL Technologies Human Recombinant PDGF-BB ACF
Platelet-derived growth factor, animal component-free - 10 Ug
STEMCELL Technologies Human Recombinant CCL19 MIP-3
Chemokine ligand 19 or macrophage inflammatory protein-3 beta - 100 Ug
Abcam N-(p-Coumaroyl)serotonin, Antibacterial agent, 25MG
MW 322.36 g/mol, Purity >95%. An antioxidative phenolic naturally found in plants, including safflower seed and millet grain. Inhibits the production of proinflammatory cytokines by LPS-stimulated human blood monocytes. It is believed that this inhibition is a result of the partial down-regulation of cytokine mRNA levels and inhibition of NF-κB activation. Ameliorates atherosclerosis in vivo, reducing lesion area in mice and rabbits. Augments fibroblast proliferation, and promotes relaxation of vascular smooth muscle cells in vitro. Functions as an antioxidant, inhibiting the effects of high glucose-induced cell death, caspase-3 activation, and the overproduction of the mitochondrial superoxide.
The product is subject to the following: Abcam Restricted Use Statement
Abcam N-(p-Coumaroyl)serotonin, Antibacterial agent, 10MG
MW 322.36 g/mol, Purity >95%. An antioxidative phenolic naturally found in plants, including safflower seed and millet grain. Inhibits the production of proinflammatory cytokines by LPS-stimulated human blood monocytes. It is believed that this inhibition is a result of the partial down-regulation of cytokine mRNA levels and inhibition of NF-κB activation. Ameliorates atherosclerosis in vivo, reducing lesion area in mice and rabbits. Augments fibroblast proliferation, and promotes relaxation of vascular smooth muscle cells in vitro. Functions as an antioxidant, inhibiting the effects of high glucose-induced cell death, caspase-3 activation, and the overproduction of the mitochondrial superoxide.
The product is subject to the following: Abcam Restricted Use Statement
Biolegend LEGENDplex™ Buffer Set A3 Apps: Multiplex - Component; Size: 100 tests
LEGENDplex™ Buffer Set A3 Apps: Multiplex - Component; Size: 100 tests
Biolegend Cell-Vive™ Ultra-LEAF™ Defined Human TruStain FcX™, GMP Apps: FC; Size: 100 tests
Cell-Vive™ Ultra-LEAF™ Defined Human TruStain FcX™, GMP Apps: FC; Size: 100 tests
Biolegend Zombie YG581™ Fixable Viability Kit Apps: FC; Size: 500 tests
Zombie YG581™ Fixable Viability Kit Apps: FC; Size: 500 tests