Native Proteins and Derivatives
Cayman Chemical 3AmIno3deoxyadenosIn5 2.1mg
An agonist of PPARa activates PPARa in HepG2 cells in a reporter assay at 1 UM but does not activate PPARB or PPARY at 10 UM prevents T0901317-induced triglyceride accumulation in HepG2 cells at 3 UM scavenges ROS and peroxynitrite in cell-free assays (IC50s 39.7 and 2.39 UM respectively) inhibitsBglucuronidase and tyrosinase (IC50s 8.9 and 0.01 UM for the bovine liver and mushroom enzymes respectively) reduces age-induced increases in liver weight and triglyceride levels in a rat model of hepatic steatosis at 5 mg/kg
Cayman Chemical 3OMethylgunosIn5OtrI 2.7mg
A lignan scavenges ABTS radicals in a cell-free assay (IC50 19.4 UM) inhibits LPS-induced NO production in RAW 264.7 macrophages (IC50 84.45 UM) inhibits AB42 self-aggregation in a cell-free assay at 20 UM
Cayman Chemical Rp2DeoxyadenosIn5O 1 2.1mg
An ETA receptor antagonist (Ki 13 nM in rat aortic vascular smooth muscle cells) inhibits ET-1-induced contractions in isolated rat aortic rings and mesenteric microvessels (pA2s 8.1 and 7.97 respectively) decreases systolic blood pressure in DOCA-salt hypertensive rats at 50 mg/kg decreases MAP and LVDP in normotensive pigs at 1 and 5 mg/kg reduces myocardial infarct size as a percentage of the area at risk in a porcine model of LAD coronary artery ligation-induced ischemia-reperfusion injury
Biocare Medical, LLC Factor XIIIa Antibody - Concentrate, 1.0 ml
This is a monoclonal antibody to the A-subunit of human coagulation Factor XIII. Studies have shown it recognizes human Factor XIII Achain in both reduced and non-reduced forms. It does not react with human Factor XIII B-chain or human Factor XII. Factor XIII is a betaglobulin found in plasma and is composed of two subunits. Factor XIIIA is the catalytic subunit and is a dimer of M.W. 160,000. According to studies, Factor XIII is present in plasma as an alpha2beta2 heterodimer (M.W. 320,000); whereas in platelets, only the alpha2 unit exists. Factor XIIIa is a dermal dendrocyte marker and shows variable reaction with these types of tumors (3,4). It can be used for histiocytic phenotyping and has been reported to mark capillary hemangiomas and tumors of the central nervous system (1-6). Factor XIIIa has also been used with CD34 to differentiate between dermatofibroma and dermatofibrosarcoma protuberans (3).
Sigma Aldrich Fine Chemicals Biosciences fibronectin bovine plasma5MG
fibronectin is a glycoprotein with multiple domains. It comprises a N-terminal central binding domain and a heparin-binding domain. Bovine plasma fibronectin has polypeptide chains with disulfide linkage and corresponds to a molecular weight of 220 and 215 kDa.
Sigma Aldrich Fine Chemicals Biosciences fibronectin bovine plasma1MG
fibronectin is a glycoprotein with multiple domains. It comprises a N-terminal central binding domain and a heparin-binding domain. Bovine plasma fibronectin has polypeptide chains with disulfide linkage and corresponds to a molecular weight of 220 and 215 kDa.
Sigma Aldrich Fine Chemicals Biosciences Thrombin Protease Cytiva 2
Thrombin is a protease used to digest fusion proteins prepared from pGEX vectors recognition sequence for thrombin (pGEX-1lT pGEX-2T pGEX-2TK pGEX-4T-1 pGEX-4T-2 and pGEX-4T-3). Purified from bovine plasma.Thrombin is a protease used to digest fusion proteins prepared from pGEX vectors (see pGEX Vectors (GST Gene fusion System)) containing the recognition sequence for thrombin (pGEX-1lT pGEX-2T pGEX-2TK pGEX-4T-1 pGEX-4T-2 and pGEX-4T-3).
Cayman Chemical CalpaIn InhIbItr III 10mg
A triacylglycerol containing heneicosaNIc acid groups at the sn-1 sn-2 and sn-3 positions has been used as an internal standard for the quantification of fatty acids in human breast milk samples and triacylglycerols in rat heart
American Research Products Inc Anti FN1 Fibronectin F8 IL12
Anti-Human FN1/Fibronectin (F8-IL12) Research Grade
Cayman Chemical PseudogInsenosIde F11 50mg
An internal standard for the quantification of norgestrel by GC- or LC-MS
Cayman Chemical 17mthyl StearIc ACD mthyl 20mg
A semisyntheticBlactam antibiotic active against clinical isolates of methicillin-susceptible S. aureus and penicillin-susceptible S. pneumoniae as well as group A group B and viridans group streptococci in vitro (MIC90s 0.06-2 Ug/ml) less effective toward other bacteria (MIC90 16 Ug/ml for S. epidermidis S. haemolyticus E. faecalis E. faecium MRSA and penicillin-intermediate and -resistant S. pneumoniae) targets the bacterial cell wall inhibits S. pneumoniae penicillin-binding proteins 1a 1b 2a 2b and 3 in vitro (IC50s 0.17-1.75 UM) inhibits growth of S. aureus in a thigh model of infection in mice (ED50 45.19 mg/kg s.c.)