Endothelial cells (EC) line the blood vessels of the entire circulatory system from aorta to capillaries and act as a barrier between circulating blood and the rest of the vessel wall/surrounding tissues. Endothelial cells are involved in the processes of angiogenesis vasculogenesis vasoregulation coagulation fibrinolysis and selective blood barrier. They are also implicated in pathophysiological processes including cardiovascular disease and cancer development. Cell Applications Inc. offers the widest variety of endothelial cells from different vascular beds. Matched smooth muscle cells obtained from the same arteries are available as well.The most commonly used human endothelial cells are Human Umbilical Vein Endothelial Cells (HUVEC) Human Microvascular Endothelial Cells (HMVEC) and Human Aortic Endothelial Cells (HAOEC). Select lots of HUVEC HMVEC and HAOEC have been pre-screened to demonstrate stimulation-dependent angiogenesis and key endothelial cell signaling pathwa