Lectins
Sigma Aldrich Fine Chemicals Biosciences Lectin from Phytolacca ame5MG
Lectins are carbohydrate-binding proteins omnipresent found in fungi plants and animals. The structure of lectin is diversely studied in plants and animals. The secondary structure of this protein is rich in -strands and possesses a carbohydrate binding sites on the surface.
Cayman Chemical Cholesteryl Erucate 250mg
A potent and selective FTase inhibitor (IC50 21 nM) greater than 30-fold selective for FTase over GGTase (IC50 790 nM) prevents farnesylation of Ras inhibits proliferation of cells transformed by Ras farnesylation reduces GTP-Ras decreases angiographic vasospasm and improves clinical scores in a dog model of subarachnoid hemorrhage
Cayman Chemical Cholesteryl LIgnocerate 5mg
An NSAID and a COX inhibitor (IC50s 0.9-2.7 and 1.5-20 UM for human COX-1 and COX-2 respectively) inhibits A23187-induced release of arachidonic acid in isolated rat peritoneal neutrophils and macrophages (IC50s 60 and 10 UM respectively) inhibits carrageenan-induced paw edema in rats
Cayman Chemical Cholesteryl Docosapentaenoate
A BTK inhibitor (Kis 0 91 1 6 1 3 12 6 and 3 4 nM for wild-type BTK BTKC481S BTKC481R BTKT474I and BTKT474M respectively) selective for BTK over a panel of 287 additional kinases at 1 UM inhibits anti-IgM antibody-induced BTK phosphorylation in B cells (IC50 3 1 nM) as well as anti-IgM- or CD40L-induced proliferation of B cells (IC50s 1 2 and 1 4 nM respectively) reduces ankle thickness and cartilage damage in a rat model of collagen-induced arthritis
Cayman Chemical Cholesteryl Docosapentaenoate
A BTK inhibitor (Kis 0 91 1 6 1 3 12 6 and 3 4 nM for wild-type BTK BTKC481S BTKC481R BTKT474I and BTKT474M respectively) selective for BTK over a panel of 287 additional kinases at 1 UM inhibits anti-IgM antibody-induced BTK phosphorylation in B cells (IC50 3 1 nM) as well as anti-IgM- or CD40L-induced proliferation of B cells (IC50s 1 2 and 1 4 nM respectively) reduces ankle thickness and cartilage damage in a rat model of collagen-induced arthritis
Cayman Chemical Cholesteryl LInoleate 50mg
A limonoid triterpenoid reduces HIV-1 replication in infected PBMCs (EC50 52 2 M) dose-dependently reduces HUVEC proliferation invasion tube formation and MMP-2 and MMP-9 activity at 5-25 g/ml increases GST activity in small intestinal mucosa liver and forestomach homogenates of mice by 4 17- 3 44- and 1 16-fold respectively at 10 mg increases TGR5-dependent luciferase activity 5 5-fold in HEK293 cells at 100 M completely prevents weight gain and reduces serum glucose and insulin levels by 30 and 89 8 respectively in mice fed a high-fat diet at 0 2 increases the white blood cell count and the specific antibody titer in blood by approximately 10-fold in mice in response to sheep red blood cells at 10 mol/kg
Cayman Chemical Cholesteryl Heptadecnoate 50mg
A PEGylated building block has been used as a linker to conjugate folic acid to 12-DSPE as a component in the formation of doxorubicin-containing liposomes with anticancer activity has been conjugated to oleanolic acid which improves oleanolic acid-induced inhibition of cell proliferation by 677-fold in HepG2 cells
Cayman Chemical Cholesteryl LInoleate 500mg
A microbial monosaccharide has been found in the cell wall of bacteria such as S bovis and in the O-specific polysaccharide of LPS in species including E coli and P maltophilia a component of the surface glycopeptidolipids of M avium
Cayman Chemical D-Galactose 1kg
A mixed-type non-competitive inhibitor of telomerase (IC50 93 nM) that has little effect on several mammalian DNA and RNA polymerases bacterial DNA helicase or HIV-1 reverse transcriptase induces senescence or apoptosis in cancer cells
Cayman Chemical Plnt Tomato TomatIn 25mg
Induces the differentiation of MHC-positive cardiomyocytes from embryonic stem cells with an EC50 value of 0.1 UM
Cayman Chemical PHA-767491hydrochlorIde 50mg
A nucleoside analog and prodrug form of ara-CTP triphosphorylated to ara-CTP by the successive actions of deoxycytidine kinase deoxycytidylate kinase and nucleoside diphosphate kinase inhibits proliferation of HL-60 ML-1 Raji and Jurkat human leukemia cell lines (IC50s 37 17 16 and 72 nM respectively) induces cell cycle arrest at the G0/G1 phase in HL-60 cells at 2.5 and 15 UM reduces tumor growth and increases tumor caspase-3 activity in an MOLM-13 mouse xenograft model at 75 mg/kg per day intraperitoneally increases survival and reduces brain herpesvirus titers in infected rats at 80 and 320 mg/kg subcutaneously
Biolegend Spark RedTM 718 anti-human CD4
Spark Red™ 718 anti-human CD45 [2D1]; Isotype: Mouse IgG1, κ; Reactivity: Human; Apps: FC; Size: 25 tests