Cell Culture Media, Supplements, and Reagents
Medchemexpress LLC HY-15427 5mg Medchemexpress, GDC-0834 CAS:1133432-49-1 Purity:>98%
Medchemexpress, HY-15427 5mg GDC-0834 CAS:1133432-49-1 GDC-0834 is a potent and selective BTK inhibitor. GDC-0834 inhibits BTK with an in vitro IC50 of 5.9 and 6.4 nM in biochemical and cellular assays, respectively, and in vivo IC50 of 1.1 and 5.6 μM in mouse and rat, respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Apexbio Technology LLC Puromycin aminonucleoside(Synonyms: Puromycin Aminonucleoside, Puromycin Nucleoside, 3'-Amino-3'-deoxyadenosine, PAN, NSC 3056, Puromycin Aminonucleosid, Adenosine, 3'-amino-3'-deoxy-), 50mg, CAS: 58-60-6.
Puromycin aminonucleoside (CAS 58-60-6) is the aminonucleoside moiety derived from the antibiotic puromycin It induces nephrotic injury in experimental animal models leading to significant proteinuria and structural alterations in renal glomeruli In vitro treatment with puromycin aminonucleoside alters podocyte morphology characterized by reductions in cellular microvilli and disruption of foot-process structures In vivo administration in rats induces glomerular lesions resembling focal segmental glomerulosclerosis (FSGS) and lipid accumulation in mesangial cells This compound serves primarily as an investigative tool in elucidating mechanisms underlying nephrotic syndrome
Selleck Chemical LLC Spectinomycin 2HCl S2510-50mg
Spectinomycin 2HCl (Actinospectacin) is a new parenteral antibiotic prepared from Streptomyces spectabilis
Medchemexpress LLC HY-101243 5mg Medchemexpress, XMD16-5 CAS:1345098-78-3 Purity:>98%
Medchemexpress, HY-101243 5mg XMD16-5 CAS:1345098-78-3 XMD16-5 is a potent TNK2 inhibitor with IC 50 values of 16 and 77 nM for the D163E and R806Q mutations, respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Bioworld Thidiazuron (TDZ), 1 g
Thidiazuron (TDZ)Synonym: Phenyl-N'-(1,2,3-thiadiazol-5-yl) ureaCytokinin like growth regulator Absorbed via the leafPlant cell culture testedAppearance: white to off-white powderMelting Point: 210.5-212.5 ºCSoluble in DMSOIrritating to eyes, respiratory system and skin; do not breathe dustSolubilizeat 1 mg/mLin 0.1N KOH
Medchemexpress LLC HY-101039A 5mg Medchemexpress, AR-M 1000390 (hydrochloride) CAS:209808-47-9 Purity:>98%
Medchemexpress, HY-101039A 5mg AR-M 1000390 (hydrochloride) CAS:209808-47-9 AR-M 1000390 hydrochloride is an exceptionally selective, potent δ opioid receptor agonist with an EC 50 of 7.2±0.9 nM for δ agonist potency. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HZX-02-059 | 2240205-30-3 | 99.4% | 487.48 | 50 MG
HZX-02-059 is a potent methuosis inducer and dual-target PIKfyve/tubulin inhibitor with anticancer activity. Methuosis primarily disrupts the balance of endocytosis and exocytosis, leading to the formation of numerous vesicles and inducing cell death. This compound also induces cell vacuolization, promotes apoptosis, downregulates the p53 pathway, inhibits PI3K/AKT phosphorylation, and inhibits c-Myc and NF-κB transcription.
- Potent methuosis inducer
- Dual-target PIKfyve/tubulin inhibitor
- Anticancer activity
- Induces cell vacuolization
- Promotes apoptosis
- Downregulates the p53 pathway
- Inhibits PI3K/AKT phosphorylation
- Inhibits c-Myc and NF-κB transcription
Enzo Life Sciences Irsogladine. maleate (50mg). CAS: 84504-69-8
Irsogladine is a selective PDE4 inhibitor which also enhances gap junction intercellular communication. It inhibits angiogenesis in wild-type and plasminogen activator-deficient mice. Purity: ≥98% (UHPLC). Solubility: Soluble in DMSO (25 mg/ml). Long Term Storage: Ambient.
Medchemexpress LLC Vancomycin (hydrochloride) | 1404-93-9 | 99.47% | 1450 Da | 250 MG
Vancomycin hydrochloride is an antibiotic used for treating bacterial infections. It functions by inhibiting the second stage of cell wall synthesis in susceptible bacteria. Additionally, vancomycin modifies the cell membrane's permeability and selectively suppresses ribonucleic acid synthesis.
- Inhibits bacterial cell wall synthesis.
- Alters cell membrane permeability.
- Selectively inhibits ribonucleic acid synthesis.
- Active against many Gram-positive bacteria, including *Staphylococcus aureus* and enterococci.
- Glycopeptide compound.
Medchemexpress LLC Loratadine-d5 | 1398065-63-8 | 99.96% | 387.91 | 5 MG
Loratadine-d5 is the deuterium labeled Loratadine. Loratadine (SCH-29851) is a selective inverse peripheral histamine H1-receptor agonist with an IC50 of >32 μM. It has anti-dengue-virus (DENV) activity and can inhibit immunologic release of inflammatory mediators. It can be used as a tracer or an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS. Deuteration has gained attention due to its potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Selective inverse peripheral histamine H1-receptor agonist.
- Has anti-dengue-virus (DENV) activity.
- Can inhibit immunologic release of inflammatory mediators.
- Can be used as a tracer or an internal standard for quantitative analysis.
- Deuteration can affect the pharmacokinetic and metabolic profiles of drugs.
Apexbio Technology LLC Zaltoprofen 74711-43-6 10mg
Zaltoprofen (CAS 74711-43-6) is a nonsteroidal anti-inflammatory small molecule that functions as a cyclooxygenase (COX) inhibitor with a moderate selectivity for COX-2 over COX-1 (IC50 values of 0 34 M for COX-2 and 1 3 M for COX-1) In addition to inhibiting prostaglandin synthesis through COX modulation zaltoprofen has been shown to suppress bradykinin-induced nociceptive responses independent of its COX-inhibitory activity This multifaceted mechanism makes zaltoprofen a relevant tool for investigating inflammatory pathways and pain signaling in biomedical research
Apexbio Technology LLC Amoxicillin trihydrate 61336-70-7 1g
Amoxicillin trihydrate (CAS 61336-70-7) is a small-molecule inhibitor targeting bacterial cell wall synthesis It is designed to inhibit peptidoglycan cross-linking thereby disrupting bacterial cell wall biosynthesis and resulting in cell lysis Amoxicillin trihydrate exerts its biological activity primarily through inhibition of bacterial transpeptidase enzymes involved in cell wall synthesis In in vitro studies Amoxicillin trihydrate demonstrates bactericidal activity with reported minimum inhibitory concentration (MIC) values of approximately 0 01 g/ml for Streptococcus viridans 0 25 g/ml for Bacillus anthracis and 50 g/ml for Retterella indica Based on these pharmacological properties Amoxicillin trihydrate holds research potential in antibacterial susceptibility testing microbial growth inhibition studies and in vitro pharmacological investigations