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Diketone-PEG4-PFP ester is a PEG-based PROTAC linker used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one for an E3 ubiquitin ligase and the other for the target protein. They exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. This product is for research use only and not sold to patients.
PEG-based PROTAC linker
Used in the synthesis of PROTACs
Utilizes the intracellular ubiquitin-proteasome system
Selectively degrades target proteins
For research use only
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An ester prodrug form of PGE1; exhibits a faster penetration flux than the free acid form of PGE1 when applied topically to isolated mouse skin; topical administration reduces fluid pressure within human dermal fibroblast cell aggregates at 1 mM
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
An ester prodrug form of PGE1; exhibits a faster penetration flux than the free acid form of PGE1 when applied topically to isolated mouse skin; topical administration reduces fluid pressure within human dermal fibroblast cell aggregates at 1 mM
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
Diketone-PEG4-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
PEG-based PROTAC linker
Can be used in the synthesis of PROTACs
Contains two different ligands connected by a linker
Exploits the intracellular ubiquitin-proteasome system
Selectively degrades target proteins
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
We are committed to bringing you Greener Alternative Products which adhere to one or more of The 12 Principles of Greener Chemistry. This product has Inherently Safer Chemistry compared to the standard use of phenol and chloroform to perform DNA extractions.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
M-PEG4-CH2-methyl ester is a PEG- and Alkyl/ester-based PROTAC linker. It is utilized in the synthesis of PROTACs, which are designed to selectively degrade target proteins by exploiting the intracellular ubiquitin-proteasome system.
Can be used in the synthesis of PROTACs
Exploits the intracellular ubiquitin-proteasome system
Molecular weight of 264.32
Appears as a colorless to light yellow liquid
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More