Tryptic Soy Broth, Modified with Novobiocin & Acid Digest of Casein is used for the selective enrichment of enterohemorrhagic E. coli in foods. Conforms to USDA Formulation with Novobiocin supplementation in a laboratory setting. Tryptic Soy Broth, Modified with Novobiocin & Acid Digest of Casein is not intended for use in the diagnosis of disease or other conditions in humans. The first major outbreak of E. coli O157:H7 was in 1982, and traced to contaminated hamburgers. Other known sources of infection include sprouts, lettuce, salami, unpasteurized milk, juice and/or swimming in or drinking contaminated water. Tryptic Soy Broth, Modified with Novobiocin & Acid Digest of Casein is used to enrich food samples suspected of having low levels of EHEC during pathogen testing.For more information visit https://www.neogen.com/solutions/Microbiology/tryptic-soy-broth-modified-with-8-mg-novobiocin-and-acid-digest-casein