CAS RN 28097-03-2
CAS RN 28097-03-2
IUPAC Name:
14-(hydroxymethyl)-3-[14-(hydroxymethyl)-18-methyl-13,17-dioxo-15,16-dithia-10,12,18-triazapentacyclo[12.2.2.0¹,¹².0³,¹¹.0⁴,⁹]octadeca-4,6,8-trien-3-yl]-18-methyl-15,16-dithia-10,12,18-triazapentacyclo[12.2.2.0¹,¹².0³,¹¹.0⁴,⁹]octadeca-4,6,8-triene-13,17-dione
Synonyms:
chaetocin
Molecular Weight (g/mol):
696.83
Molecular Formula:
C30H28N6O6S4
InChi Key:
PZPPOCZWRGNKIR-UHFFFAOYNA-N
SMILES:
CN1C(=O)C23CC4(C(NC5=CC=CC=C45)N2C(=O)C1(CO)SS3)C12CC34SSC(CO)(N(C)C3=O)C(=O)N4C1NC1=CC=CC=C21
1
–
2
of
2
results
1
Tocris Bioscience™ Chaetocin
CAS: 28097-03-2 Molecular Formula: C30H28N6O6S4
2
MilliporeSigma™ Calbiochem™ HMTase Inhibitor II, Chaetocin
A naturally occurring cell-permeable Chaetomium fungal epi-dithio-diketopiperazine that potently inhibits the H3K9 histone methyltransferase activity of Drosophila melanogaster SU(VAR)3-9 and its human homologue SUV39H1 (IC50 = 600 and 800 nM, respectively) in a SAM-competitive manner, while exhibiting much reduced potency against murine G9a or Neurospora crassa DIM5 H3K9 HMT (IC <sub