Histology, Cytology, and Anatomical Pathology
Fisher Scientific offers a wide range of chemicals and reagents, including histology-grade solvents, designed specifically for medical laboratory professionals.
Histology
Histology is the study of the microscopic anatomy of cells and tissues. Fisher Scientific offers a wide range of chemicals and reagents, including histology-grade solvents, designed specifically for medical laboratory professionals.
All Fisher Scientific chemicals undergo rigorous quality assurance and testing procedures. Additional benefits of choosing the Fisher Scientific brand include:
- Histology-grade solvents available in F-style poly bottle
- High-purity Optima-grade solvents available in Safe-Cote bottles
- Solvents filtered to remove particulates
Let Fisher Scientific help you find everything you need for use in your histology applications. Explore products by technical procedure:
Step One: Fixation
In the fixation stage, a fixative is used to modify tissue by stabilizing the protein, so it is resistant to further changes; thus, fixatives are used to protect tissue from degradation and to maintain the structure of the cells, including sub-cellular components, such as cell organelles (nucleus, endoplasmic reticulum and mitochondria).
Differentiators
- Extensive line of common fixatives
- "Use tested" by an independent histology lab
Step Two: Processing
In the processing stage, tissues must go through a dehydration process to replace water with the material that will be used for embedding, so the tissue samples adhere to the embedding material. The most common technique is paraffin wax embedding.
Samples are immersed in multiple baths of progressively more concentrated ethanol to remove water from the tissues, followed by a clearing agent, such as xylene, to remove the alcohol and finally hot molten paraffin wax, which replaces the xylene and infiltrates the tissue.
Differentiators
- Various ease of use packaging configurations, which include FisherLOCK tamper-evident caps, EcoSafPak shipper and F-style bottles
- Specially filtered for use in histology applications