Traditional Kinetic Jaffé Traditional Kinetic Jaffé methods are subject to severe interference by both bilirubin and hemolysis because the absorbance of these substances changes progressively with time due to oxidation or "bleaching" during the reaction. Synermed VI360 Kinetic Jaffé The Synermed kinetic creatinine decolorizes both bilirubin and hemoglobin. The background absorbance is lower thereby simplifying the spectrophotometric measurement of absorbance change and eliminating negative interference due to loss of absorbance of chromatic substances. No Interference from Serum BilirubinNo Interference from Serum HemoglobinCompares to Expensive Enzymatic Methods