Custom Rearray cDNAs, shRNAs, siRNAs, and PCR Probes

R&D Systems VersaClone cDNA, Human G-CSF R/CD114 (NP_000751)

Mutations in G-CSFR are a cause of Kostmann syndrome, also known as severe congenital neutropenia

R&D Systems VersaClone cDNA, Human CD1b (NP_001755)

The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands

R&D Systems VersaClone cDNA, Human VSIG2 (NP_055127)

VSIG2 is a type I transmembrane glycoprotein at contains multiple N-glycosylation sites in the extracellular region and phosphorylation sites in the cytoplasmic tail.

R&D Systems VersaClone cDNA, Human IL-27 R alpha/WSX-1/TCCR (NP_004834)

IL27RA is involved in the regulation of Th1 type immune responses. It may also be involved in innate defense mechanisms

R&D Systems Mouse VISTA/B7-H5/PD-1H (NP_083008) VersaClone cDNA

Chromosome 10 open reading frame 54; GI24

R&D Systems VersaClone cDNA, Mouse BMPR-IA/ALK-3 (NP_033888)

BMPR1A is one of seven known type I serine/threonine kinases that are required for the signal transduction of TGF-β family cytokines

R&D Systems Human VSIG8 (NP_001013683) VersaClone cDNA

V-Set and Immunoglobulin Domain Containing 8

R&D Systems VersaClone cDNA, Mouse PD-L2/B7-DC (NP_067371)

The extracellular domains of mouse and human PD-L2 share approximately 72% amino acid sequence identity

R&D Systems VersaClone cDNA, Human VSIG3 (NP_001015887)

VSIG3/IGSF11 is an adhesion molecule that forms Ca-independent homophilic interactions

R&D Systems Human GlyT1/SLC6A9 (NP_964012) VersaClone cDNA

DKFZp547A1118; GlyT1; GlyT-1; GLYT1glyT-1

R&D Systems VersaClone cDNA, Human ABCB5 (NP_001157413)

ABC transporters and MDR will likely be important in the therapeutic optimization for cancer patients

R&D Systems VersaClone cDNA, Human IL-31 RA (NP_620586)

IL31RA is also expressed on keratinocytes, dorsal root ganglia neurons, and variably on lung epithelial cells

R&D Systems Human TGF-beta RI/ALK-5 (NP_004603) VersaClone cDNA

Transforming Growth Factor beta Receptor I

R&D Systems VersaClone cDNA, Mouse EphB1 (NP_775623)

Eph and Eph-related receptors have been implicated in mediating developmental events, particularly in the nervous system. It may also be involved in carcinogenesis of the digestive tract

R&D Systems VersaClone cDNA, Human IL-12 R beta 2 (NP_001550)

IL-12 R beta 1 binds specifically to IL-12 p40, a subunit of the heterodimeric IL-12, and is also a subunit of the IL-23 receptor complex, while IL-12 R beta 2 binds IL-12 p35

R&D Systems VersaClone cDNA, Human VSIG4 (NP_009199)

VSIG4 contributes significantly to innate immunity by binding and phagocytosis of complement opsonized invading pathogens

R&D Systems Human IL-10 R beta (NP_000619) VersaClone cDNA

D21S58; IL-10R2; IL10RB; CDw210b antigen

R&D Systems VersaClone cDNA, Human IL-12 R beta 1 (NP_005526)

IL-12 R beta 1 binds specifically to IL-12 p40, a subunit of the heterodimeric IL-12, and is also a subunit of the IL-23 receptor complex, while IL-12 R beta 2 binds IL-12 p35

R&D Systems VersaClone cDNA, Mouse GPR35 (NP_071715)

GPR53 acts as a receptor for kynurenic acid, an intermediate in the tryptophan metabolic pathway

R&D Systems Mouse CEACAM-2 (NP_001106839) VersaClone cDNA

Carcinoembryonic Antigen-related Cell Adhesion Molecule 2

R&D Systems VersaClone cDNA, Human Fas/TNFRSF6/CD95 (NP_000034)

The interaction of FAS with its ligand allows the formation of a death-inducing signaling complex that includes Fas-associated death domain protein (FADD), caspase 8, and caspase 10

R&D Systems Human LILRB2/CD85d/ILT4 (NP_005865) VersaClone cDNA

Leukocyte Immunoglobulin-like Receptor, Subfamily B (with TM and ITIM Domains), Member 5

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