
Karl Fischer Buffers and Reagents
Buffers and reagents intended for use with Karl Fischer (KF) titration techniques. KF titration is a classic titration method that uses coulometric or volumetric titration to determine the moisture content of a sample.
Karl Fischer (KF) reagents are used in the analytical technique developed by chemist Karl Fischer to accurately measure the water content of gases, liquids, and solids.
Key applications include:
- Analyzing water content in raw materials and finished products
- Estimating moisture in food, pharmaceuticals, chemicals, and petroleum products
- Determining the water content of laboratory samples.
Karl Fischer reagents contain a variety of chemicals in proprietary formulations. Consult the SDS for individual products for appropriate handling instructions and precautions.
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Filtered Search Results

MDL Number | 81734 |
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Packaging | Amber glass bottle |
Physical Form | Liquid |
Karl Fischer Aqualine™ Titrant 5, for Karl Fischer Titration By Volumetry, Fisher Chemical
For two-component system. Water equivalent: 5.0mg H2O/mL

HYDRANAL™ - Coulomat AG, Reagent for coulometric KF titration (anolyte solution), for cells with and without diaphragm, Honeywell Fluka™
SureTRACE
Supports traceability with guaranteed access to certificates and proactive change notifications.
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Supports traceability with guaranteed access to certificates and proactive change notifications.
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CAS | 288-32-4 |
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UN Number | UN1230 |
HYDRANAL™ - CRM Water Standard 1.0, Certified reference material for Karl Fischer titration (water content 1 mg/g = 0.1%), Honeywell Fluka™

Molecular Formula: C7H8O Molecular Weight (g/mol): 108.14 InChI Key: RDOXTESZEPMUJZ-UHFFFAOYSA-N PubChem CID: 7519 ChEBI: CHEBI:16579 IUPAC Name: anisole SMILES: COC1=CC=CC=C1

PubChem CID | 7519 |
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Molecular Weight (g/mol) | 108.14 |
ChEBI | CHEBI:16579 |
SMILES | COC1=CC=CC=C1 |
IUPAC Name | anisole |
InChI Key | RDOXTESZEPMUJZ-UHFFFAOYSA-N |
Molecular Formula | C7H8O |
Karl Fischer Aqualine™ Complete 5, for Karl Fischer Titration By Volumetry, Fisher Chemical™
Single-component reagent; Pyridine free
Name Note | Karl Fischer Reagent |
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CAS | 7553-09-5 |
Health Hazard 3 | Emergency Overview Causes burns by all exposure routes. Harmful by inhalation. Possible risk of harm to the unborn child. NFPA Health: |
Health Hazard 2 | DANGER! |
Color | Brown |
Physical Form | Liquid |
Health Hazard 1 | Signal Word: DANGER! |
Chemical Name or Material | Aqualine™ Complete 5 |
Cleanup Symbol | Solvent |
ChemAlert Storage Symbol | Gray |
Karl Fischer Aqualine™ Electrolyte AG, for Karl Fischer Titration By Coulometry, Fisher Chemical™
Nonhalogenated anolyte solution for general use in conventional cells with a diaphragm
Karl Fischer Aqualine™ Solvent, for Karl Fischer Titration By Volumetry, Fisher Chemical™
Solvent for two-component system; Pyridine free
Name Note | Karl Fischer Reagent |
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CAS | 288-32-4 |
MDL Number | 81734 |
Color | Colorless |
Packaging | Amber glass bottle |
Physical Form | Liquid |
Health Hazard 1 | GHS Signal Word: Danger |
UN Number | 1992 |
DOT Information | DOT Class 3, : Flammable Liquid |
Chemical Name or Material | Aqualine™ Solvent |
Cleanup Symbol | Solvent |
ChemAlert Storage Symbol | Red |
HYDRANAL™ - Composite 2, Reagent for volumetric one-component Karl Fischer titration (methanol free), Honeywell™ Fluka™
SureTRACE
Supports traceability with guaranteed access to certificates and proactive change notifications.
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Supports traceability with guaranteed access to certificates and proactive change notifications.
Learn More


CAS | 111-90-0 |
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HYDRANAL™ - Composite 5, Reagent for volumetric one-component Karl Fischer titration (methanol free), Honeywell™ Fluka™
SureTRACE
Supports traceability with guaranteed access to certificates and proactive change notifications.
Learn More

Supports traceability with guaranteed access to certificates and proactive change notifications.
Learn More


CAS | 111-90-0 |
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HYDRANAL™ - Composite 5 K, Reagent for volumetric one-component Karl Fischer titration in aldehydes and ketones (methanol free), Honeywell™ Fluka™
SureTRACE
Supports traceability with guaranteed access to certificates and proactive change notifications.
Learn More

Supports traceability with guaranteed access to certificates and proactive change notifications.
Learn More


CAS | 111-90-0 |
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HYDRANAL™ - Water Standard 1.0, Standard for Karl Fischer titration (water content 1 mg/g = 0.1%), verified against NIST SRM 2890 & NMIJ CRM 4222, Honeywell™ Fluka™
SureTRACE
Supports traceability with guaranteed access to certificates and proactive change notifications.
Learn More

Supports traceability with guaranteed access to certificates and proactive change notifications.
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HYDRANAL™ - Methanol dry, Reagent for volumetric one-component KF titration (working medium), Honeywell Fluka™
SureTRACE
Supports traceability with guaranteed access to certificates and proactive change notifications.
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Supports traceability with guaranteed access to certificates and proactive change notifications.
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Synonym | Coulometric Single Solution |
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MDL Number | 240423 |
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