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Chemical Resource Center

Chemical Resource Center

Find more detailed product information and resources for Thermo Scientific™, Fisher Chemical™, Fisher BioReagents™, Acros Organics™, Alfa Aesar™ and Maybridge™ products.

Chemical Essentials Handbook

New Fisher Scientific Chemical Essentials Handbook

In this handbook, you’ll find a selection of essential chemicals for analysis, synthesis, inorganic, and life sciences applications. Plus, read key information on safe storage, handling, and packaging to support your chemistry.

Download Now (PDF, 6.2MB)

Fisher Scientific Glove Sizing Guide

Selecting the right glove size means a comfortable, safe fit and helps ensure that workers will wear their gloves. Use this simple guide to find your glove size.

 

Glove Sizing Guide

Maybridge Hit-to-Lead Building Blocks Flyer

Hit-to-Lead Building Blocks... by and for medicinal chemists for medicinal chemists. Find the molecules you need.

Building Blocks Flyer

Fisher Chemical Resistance of Plastic Technical Bulletin

General guides for chemical resistance and physical properties of plastics.

Plastic Technical Bulletin

NMR Proton Shifts for Residual Solvent Impurities

This chart provides reference information about NMR proton shifts for residual solvent impurities (following GHS guidelines).

 

Residual Solvent Impurities

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Fisher Scientific Common Equations Technical Reference Guide

The technical reference guide includes: units of concentration, dilution equations, normality calculations, molar fraction, chemical alert storage codes and more.

Fisher Scientific Common Equations Technical Reference Guide (1.8 MB)

Fisher Scientific Tubing Sizer Guide

The Tubing Sizer Guide includes many of the most popular tubing sizes. Simply place your current tubing on top of the sizing chart to determine the best size for your needs.

Fisher Scientific Tubing Sizer Guide (342.3 KB)

Fisher Scientific Atomic Weights Data Sheet

The datasheet includes a list of the element's name, symbol, atomic number and atomic weight.

 Fisher Scientific Atomic Weights Data Sheet (89.1 KB)

Fisher Chemical and Fisher BioReagents Workflow Wheel

Use this wheel to find the chemicals needed for your analytical and life sciences research.

Fisher Chemical and Fisher BioReagents Workflow Wheel (2 MB)

Acros Organics and Alfa Aesar Workflow Wheel

Use this wheel to find Acros Organics and Alfa Aesar chemicals, metals and materials for research and development.

Acros Organics and Alfa Aesar Workflow Wheel (3.6 MB)


Fisher Scientific Chemical Essentials Handbook

Find chemicals for analysis, synthesis, inorganic, and life sciences applications and key information on safe storage, handling, and packaging.

 

Chemical Essentials Handbook

Fisher Chemical Stockroom Handbook

Within the handbook, you’ll find storage recommendations, chemical compatibility charts and recommended essential products to stock to accommodate various research applications.

 

Brouchers Chemical Stockroom Handbook

Acros Organics Acroseal Packaging Catlog

See how AcroSeal packaging protects organic solvents and pyrophoric and hazardous reagents that are sensitive to air and moisture.

 

Brouchers Acros Organics Acro Seal Packaging

Fisher BioReagents Buffers for Life Sciences Reasearch Brochure

Buffers for Life Sciences Research. CellPURE Biological Buffers | JustPURE “Good” Buffers | Core Essential Buffers

 

Brouchers Fisher Bio Reagents Buffers

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Fisher Chemical Histology Brochure

The Fisher Chemical Histology Brochure includes a product selection guide for: fixation, processing, embedding, sectioning, and staining.

Fisher Chemical Histology Brochure (1.7 MB)

Thermo Fisher Scientific Chemical Brands Overview

Browse our wide range of chemicals and reagents and learn about our packaging enhancements and how we can provide specialized services through our partnership with you.

Thermo Fisher Scientific Chemical Brands Overview (1.7 MB)

Fisher Chemical Tracemetal Grade Acids and Base Brochure

Read about the key features and packaging advantages of Fisher Chemical trace metal grade acids and bases.

Fisher Chemical Tracemetal Grade Acids and Base Brochure (1.4 MB)

LC/MS Guide: Increase Analytical Accuracy

An overview of solvents, blends, standards, surfactants, and acids to use when performing liquid chromatography/mass spectrometry work.

 LC/MS Guide: Increase Analytical Accuracy  (1.9 MB)

Fisher Chemical and Thermo Scientific Solvents Application Guide

Find out more about Fisher Chemical innovative packaging solutions and products offering purity grades for every application.

 Fisher Chemical and Thermo Scientific Solvents Application Guide (8.8 MB)

Fisher Chemical Inorganic Salts Guide

Our Specialized Chemical Services provide tailored chemical solutions and services required in research, scale-up, development and production.

Fisher Chemical Inorganic Salts Guide (542.5 KB)

Protein Electrophoresis Guide

An overview of Fisher BioReagents EZ-Run Protein Gel Solution, EZ-Run Protein Standards, EZ-Run Gel Staining Solution and traditional SDS-PAGE Reagents.

 Protein Electrophoresis Guide (885.9 KB)


New Solvent Grade Targeted for Trace Trace Analysis by UHLC-MS White Paper

Learn about a new solvent grade for mobile phases targeting UHPLC-MS that will show a very low-mass noise level in both positive and negative mode ionization, minimal metal ion content and very low UHPLC-UV response using photodiode array detection.

 

Publications Targeted For Trace Analysis

High Speed SDS-Page of Proteins Poster

Learn about the Thermo Scientific FASTRun buffer, which can be used at higher voltages without generating heat that could impact the clarity of the protein bands.

 

Publications High Speedsds Page

Acros Organosilanes in Organic Chemistry Publication

See how four of the most important applications of organosilanes from the Acros portfolio can meet your organic chemistry needs.

 

Publicatios Acros Organosilanes

Plasma and Brain Fatty Acid Profiles in Alzheimer's Disease Publication

Read the findings of the National Institutes of Health - Plasma and Brain Fatty Acid Profiles in Mild Cognitive Impairment and Alzheimer’s Disease.

 

Publications Plasma And Brain Fatty Acid

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Formic Acid - Ammonium Formate Buffer System for LC/MS Analysis of Vitamin D Study

In this study, acidic buffer system for mobile phase solutions was evaluated for trace level analysis of 25- OH vitamin D2 using ESI-LC/MS.

Formic Acid - Ammonium Formate Buffer System for LC/MS Analysis of Vitamin D Study (231.6 KB)

New Solvent Grade Targeted for Trace Analysis White Paper

Fisher Chemical has developed a new solvent grade, UHPLC-MS Optima, for mobile phases targeting trace analysis by UHPLC-MS.

New Solvent Grade Targeted for Trace Analysis White Paper (551.1 KB)

Enhanced LC-MS Sensitivity of Vitamin D Assay White Paper

Learn why liquid chromatography mass spectrometry is the best choice for the accurate measurement of vitamin D in clinical samples.

Enhanced LC-MS Sensitivity of Vitamin D Assay White Paper(1.2 MB)

Fisher-Chemical - GCMS Impurity Profiling of Methylene Chloride Workflow Data Sheet

This study reviews Methylene Chloride, a solvent widely used in pharmaceutical, environmental and chemical industries.

Fisher-Chemical - GCMS Impurity Profiling of Methylene Chloride Workflow Data Sheet(3.6 MB)

Acros Palladium-Catalysed Coupling Chemistry White Paper

Palladium catalysis has gained widespread use in chemistry laboratories as a powerful methodology for the formation of C-C and C-Heteroatom bonds.

 Acros Palladium-Catalysed Coupling Chemistry White Paper(996.9 KB)

Fisher Chemical Ultrapure Methylene Chloride Workflow Poster

View the Fisher Chemical Ultrapure Methylene Chloride for Interference-Free Analytical Work abstract and findings.

Fisher Chemical Ultrapure Methylene Chloride Workflow Poster(2 MB)

Selection of Negative Mode Standard in LC-MS White Paper

Learn about the selection of negative mode standard in LC-MS under neutral conditions for assessing solvent quality.

 Selection of Negative Mode Standard in LC-MS White Paper(2.3 MB)

Detecting Trace Amounts of Impurity in Methylene Chloride Data Sheet

Fisher Chemical: Detecting Trace Amounts of Impurity in Methylene Chloride Results.

Detecting Trace Amounts of Impurity in Methylene Chloride Data Sheet(2.6 MB)


Analysis of Opiates, Opioids and Their Metabolities i Human Urine Application Notes

Learn about developing a quantitative forensic method for analysis of opiates opioids and their metabolites in human urine without the time-consuming step of hydrolysis.

 

Analysis of Opiates Opioids

Quantitative Analysis of Low Testosterone Concentrations in plasma Application Notes

Learn about developing an LC/MS method meeting requirements for testosterone research analysis in female and juvenile plasma.

 

Quantitative Analysis Of Low Testosterone

Quantitation of Benzoylecgonine in Urine for Workplace Drug Testing Application Notes

Learn about developing a dilute-and-shoot quantitative method that meets SAMHSA cutoffs for the confirmation of benzoylecgonine in urine.

 

Quantitation Of Benzoylecgonine In Urine

Analysis of EtG and EtS in Dilute Urine Application Notes

To develop a HPLC-MS/MS method for the forensic toxicological analysis of EtG and EtS in urine.

 

Analysis Of ETG and ETS in Dilute

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Quantitation of Phencyclidine in Urine for Workplace Drug Confirmation Testing Application Notes

Learn about developing a quantitative method that meets SAMHSA cutoffs for the confirmation of phencyclidine in urine.

Quantitation of Phencyclidine in Urine for Workplace Drug Confirmation Testing Application Notes (497 KB)

Selected-Reaction Monitoring–Mass Spectrometric Immunoassay Analysis of Parathyroid Hormone and Related Variants Application Notes

Learn about developing a SRM-MSIA-based method for the concurrent detection and quantification of full-length parathyroid hormone and two N-terminal variants for clinical research use.

 Selected-Reaction Monitoring–Mass Spectrometric Immunoassay Analysis of Parathyroid Hormone and Related Variants Application Notes (1.5 MB)

Quantitation of Immunosuppressant Drugs in Blood Application Notes

Learn about evaluating the use of a second-generation Thermo Scientific Orbitrap-based high-resolution mass spectrometer and an immunosuppressants test kit for analysis of immunosuppressant drugs in whole blood.

Quantitation of Immunosuppressant Drugs in Blood Application Notes (1.1 MB)

Quantitation of Immunosuppressant Drugs in Whole Blood Application Notes

Learn about developing a LC-MS/MS method to determine the concentrations of cyclosporine A, tacrolimus sirolimus and everolimus in whole blood.

Quantitation of Immunosuppressant Drugs in Whole Blood Application Notes (1 MB)



FASTRun Tris SDS PAGE Running Buffer, 10X Video

See why the Fisher BioReagents FASTRun Tris SDS PAGE Running Buffer, 10X, sets the new standard for running Tris-Glycine gels.

Fisher Scientific Chemical's Overview

Overview of Fisher Scientific Chemicals production.

Safe-Cote Demonstration

Fisher Chemical offers the safest chemical storage containers available, due to its Safe-Cote shatter-resistant technology. See a demonstration of a Safe-Cote bottle vs. a regular bottle to see how Safe-Cote can help protect your chemicals, your lab, and most importantly, your people.

AcroSeal Protection

What sets AcroSeal apart? No accidental removal, adhesive-free sealing for less risk of contamination, better reseal, longer product life, higher package integrity, and more.

Optima LC/MS Interview

Cara Cesario, Product Manager for Optima LC/MS Solvents, discusses how Optima solvents and blended solvents save researchers time and money, allowing them to focus on the research. Additionally, Cara reviews Specialized Chemical Services, allowing customers to order a custom blended chemical or solvent.

ChemHarmony

Find the perfect solvent match! Your highly-calibrated scanning machinery deserves high-purity, high-intensity solvents to limit metal content and background peaks. Stop looking for solvents in all the wrong places, and find perfect chemistry with Fisher Chemical Optima.

General Information

A: A one-year stability study conducted in 2011 for the storage of trace metal acids, specifically nitric acid (A509) and hydrochloric acid (A508), in polyethylene vs. glass bottles yielded the following results:

  • Overall, the trace impurity values of the metal and non-metal analytes for the product in the polyethylene packaging were similar to the product in glass after one year of storage. Also, the concentrations of the product in polyethylene packaging were far below the maximum limits in the specifications.
  • The trace impurity concentrations for some metals measured in the polyethylene packaging were not only much lower than the concentrations measured in the glass bottle for both the nitric acid and hydrochloric acid, but also were far below the maximum specification limits. In the specification tables datasheet (PDF, 188KB), these data rows are highlighted in yellow.
  • Because the trace impurity concentrations for the metal and non-metal analytes in the polyethylene bottles were below the specification limits, this data suggests that after one year of storage there was no evidence of non-hydrocarbon plasticizers or plastic byproducts leaching from the polyethylene bottles
  • In addition, Thermo Fisher Scientific has sold the following TraceMetalTM Acids products for many years in high-density polyethylene bottles:
Cat. No.Product DescriptionPackage Size
A508-4Hydrochloric Acid, TraceMetal Grade4L
A513-500Hydrofluoric Acid, TraceMetal Grade500mL
A513-4Hydrofluoric Acid, TraceMetal Grade4L
A507-4 Acetic Acid, TraceMetal Grade4L
A512-4Ammonium Hydroxide, TraceMetal Grade4L

Download the specification tables datasheet (PDF, 188KB).

A: SDS for chemicals and reagents manufactured by Fisher Chemical can be easily viewed and printed from our website.

Find out detailed SDS instructions.

A: You can download a Certificate of Analysis from this site.

Find out detailed Certificate of Analysis instructions.

If a Certificate of Analysis is not available online, please contact Fisher Chemical Technical Support at 1-800-227-6701.

A: Some of the chemicals from Fisher Chemical may not have an outdate simply because those materials do not decompose under normal storage conditions. They should have an indefinite shelf life if they are not contaminated or adulterated. If the product you purchase from Fisher Chemical has a known instability, an outdate will be noted on the label. Unless otherwise specified, the outdate will be the last day of the month indicated.  It is good chemical practice, however, not to keep chemicals beyond five years. Over extended periods of time, conditions beyond your direct control could cause degradation of even stable compounds. Generally, the first two digits of the lot number will indicate the year of manufacture.

A: Storage conditions for all Fisher Chemical products are room temperature unless otherwise stated on the label.

A: Yes, our buffer solutions—manufactured by Fisher Chemical—are directly traceable to NIST. For traceability of specific product lots to specific standard lots, obtain a Certificate of Analysis.


Chemical Grades

A: Fisher Chemical and Fisher BioReagents products are available in a wide range of purity grades to meet all applications. Please refer to the purity charts below.

View the Fisher Chemical Purity Grade Chart (PDF, 1.44MB)
View the Fisher BioReagents Purity Grade Chart (PDF, 1.MB)


Alcohol

A: The term "alcohol" can mean pure ethanol, denatured ethanol (alcohol) or other alcohols that are not ethanol (ethyl alcohol). The term "alcohol" can refer to pure alcohol -- undenatured ethanol and suitable for consumption. 

The term "alcohol" can also refer to pure alcohol at any level of concentration (proof). Therefore, "pure alcohol" is a correct term for 100% ethanol (200 proof), 95% ethanol (190 proof) and any concentration of ethanol (vodka is 40% ethanol). The term "alcohol" can refer to denatured alcohol, ethanol which is unsuitable for consumption due to the addition of toxic solvents to the pure alcohol. It can therefore refer to any denatured ethanol product, regardless of the proof of ethanol and the concentration of ethanol in the denatured product. SDA-39C is referred to as Specially denatured "alcohol", even though it contains 1% diethyl phthalate as a denaturant and even though the ethanol content of this mixture can be 190 proof or 200 proof. There are several hundred standard formulas of denatured alcohol (ethanol), all of which can be called "alcohol". The term "alcohol" can refer to other solvents which are non ethanol-based but which are chemically classified as alcohols: Isopropyl alcohol, methyl alcohol, butyl alcohol, and propyl alcohol are all "alcohol" but none are ethanol (ethyl alcohol). Since Fisher distributes a wide range of alcohol products, care must be taken when using the term alcohol, to communicate what product or class of products is being requested.

A: Specially denatured alcohol is pure ethanol rendered unfit for drinking by adding solvents such as methanol, ethyl acetate, or IPA in quantities specified by the Federal Government. The addition of these solvents is what "denatures" the pure alcohol, making it unfit for consumption. "Denatured" does not imply an altered ethanol molecule (as when a protein is denatured by heat or a chemical agent), but indicates that the ethanol is "spoiled" or "poisoned".

Certain SDAs have additives as well as denaturants. For example, SDA-38B intended for use as a mouthwash has 1percent%, all of which are determined and regulated by the BATF (Bureau of Alcohol, Tobacco and Firearms).

One of the key differences between SDAs and other denatured ethanol products (General Use Formulas) is the level of added denaturants. SDAs are typically denatured at a level between 1 and 10 percent, and the BATF considers these products capable of being undenatured. Since there is no Federal Excise Tax collected on SDAs, the BATF wants to be sure of the intended, legal application. This is the primary reason why a permit is required for use, storage or resale of SDAs.

Specially Denatured Alcohols are used in a wide variety of common products including personal care products, flavorings, fragrances and industrial-grade products. They are also used in laboratories, hospitals and research facilities. While SDAs are not taxed, customers must obtain proper permits from the BATF in order to use more than five gallons of denatured product in a one-year period. Products, which do not require a BATF permit are referred to as "General Use Formulas". Fisher has the capability of manufacturing all SDAs, but chooses not to produce certain formulas due to the carcinogenic nature of certain denaturants the extreme danger hazardous denaturants may pose.

A: Yes, but a federal excise tax must be paid. Current federal tax is $13.50 per "proof gallon," which is $27.00 per gallon for 200-proof ethanol. Fisher includes the federal excise tax in your invoice.

A: Yes, but purchases are limited to up to five gallons of SDA product in one year. A BATF permit is required to purchase more than five gallons in one year.

A: Yes. Specialized Chemical Services can supply chemicals in a wide variety of innovative packaging options designed for safety, environmental protection, convenient handling and storage and preservation of product integrity, while complying with all relevant regulations. Custom packaging is also available for chemicals supplied by you.

A: Yes. Specialized Chemical Services includes extensive in-house laboratory, QC capabilities and utilization of accredited external partners, allowing us to respond quickly to specific quality control testing at your request.