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4-Thiouridine, 98+%, PROMO, Thermo Scientific Chemicals
Description
Applications
4-Thiouridine is a constituent of several transfer RNA's. 4-Thiouridine is a thionucleobase used as an antisense agent. Widely used for RNA analysis including RNA-RNA cross coupling and RNA labelling. 4-Thiouridine is a photoreactive (crosslinking) uridine analogue that upon phosphorylation to 4-thioUTP may be incorporated into RNA structures. 4-Thiouridine may be used to study the specificity and kinetics of uridine-cytidine kinases. 4-Thio Uridine is typically used to modify oligos slated for RNA, or RNA-protein, structural studies. A 4-thio-rU modified RNA pentamer was used to study the effect of this modification on codon-anticodon interaction when it is in the wobble position of tRNA.
Solubility
Soluble in water (20 mg/mL), and methanol (10 mg/mL).
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents, heat.

Specifications
Specifications
Color | Yellow |
Quantity | 250 mg |
Solubility Information | Soluble in water, and methanol. |
IUPAC Name | 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-sulfanylidene-1,2,3,4-tetrahydropyrimidin-2-one |
Percent Purity | ≥98% |
Physical Form | Crystalline |
Chemical Name or Material | 4-Thiouridine |
Safety and Handling
EINECSNumber | 237-735-3 |
TSCA | No |
Recommended Storage | Store at -20°C |
RUO - Research Use Only
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