Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
5-Methylcytosine (5-mC) Monoclonal Antibody (A1), Active Motif™
Mouse Monoclonal Antibody
$144.60 - $572.38
Specifications
| Antigen | 5-Methylcytosine (5-mC) |
|---|---|
| Clone | A1 |
| Concentration | 1 mg/mL |
| Applications | ChIP sequencing (ChIP-seq), Dot Blot, Immunoprecipitation |
| Classification | Monoclonal |
| Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
50-199-3433
|
Active Motif
61480 |
10 μg |
Each for $144.60
|
|
|||||
|
50-199-3432
|
Active Motif
61479 |
100 μg |
Each for $572.38
|
|
|||||
Description
Methylation of DNA cytosine bases plays important roles in the regulation of gene transcription. It has been estimated that 60 to 90% of the cytosines in CpG dinucleotides are methylated. An increase in methyl-CpG correlates with transcriptional silencing for the whole chromosome especially in developmentally regulated genes. Methylation is believed to lead to transcriptional silencing by multiple mechanisms including alteration of transcription factor binding to promoters and alteration in chromatin structure.Specifications
| 5-Methylcytosine (5-mC) | |
| 1 mg/mL | |
| Monoclonal | |
| Liquid | |
| RUO | |
| PBS with 30% glycerol and 0.035% sodium azide; pH 7.5 | |
| This 5-Methylcytosine (5-mC) antibody was raised against 5-Methyl-cytidine conjugated to kLH and recognizes 5-Methylcytosine. | |
| Primary | |
| -20°C, Avoid Freeze/Thaw Cycles |
| A1 | |
| ChIP sequencing (ChIP-seq), Dot Blot, Immunoprecipitation | |
| Unconjugated | |
| Mouse | |
| Human | |
| 5mc; 5-mC; 5-meC; 5-Methyl-cytosine; C5H7NO3 | |
| IgG1 | |
| Protein A | |
| Antibody |
Spot an opportunity for improvement?Share a Content Correction
Product Content Correction
The Fisher Scientific Encompass Program offers items which are not part of our distribution portfolio. These products typically do not have pictures or detailed descriptions. However, we are committed to improving your shopping experience. Please use the form below to provide feedback related to the content on this product.
Product Title