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53BP1 Rabbit anti-Human, Mouse, Polyclonal, Bethyl Laboratories

Catalog No. 501557256
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Catalog No. Quantity
50-155-7256 100 μL
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Catalog No. 50-155-7256 Supplier Bethyl Laboratories, Inc Supplier No. A300273A
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Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt.

53BP1 (P53-binding protein 1) plays a critical role in tumor suppression and is a putative substrate of ATM kinase. Upon DNA damage, 53BP1 is phosphorylated and localizes to the presumptive sites of damage, specifically, double-strand breaks. 53BP1 may have a role in checkpoint signaling during mitosis, enhances TP53-mediated transcriptional activation, and participates in DNA repair by maintaining genomic stability.

Specifications

Antigen 53BP1
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/ml
Conjugate Unconjugated
Formulation phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene TP53BP1
Gene Accession No. P70399, Q12888
Gene Alias TP53BP1, p202
Gene Symbols TP53BP1, Trp53bp1
Host Species Rabbit
Immunogen Between 1925 and C-term
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 27223, 7158
Target Species Human, Mouse
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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