53BP2 Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-173-5372	Proteintech Group Inc 265501AP150UL	150 μL

Description

Regulator that plays a central role in regulation of apoptosis and cell growth via its interactions. Regulates TP53 by enhancing the DNA binding and transactivation function of TP53 on the promoters of proapoptotic genes in vivo. Inhibits the ability of APPBP1 to conjugate NEDD8 to CUL1, and thereby decreases APPBP1 ability to induce apoptosis. Impedes cell cycle progression at G2/M. Its apoptosis-stimulating activity is inhibited by its interaction with DDX42.

Specifications

• Antigen: 53BP2
• Applications: Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human
• Gene Accession No.: Q13625
• Gene ID (Entrez): 7159
• Immunogen: 53BP2 Fusion Protein Ag24907
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: TP53BP2

• Concentration: 0.3 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene Alias: 53BP2, ASPP2, BBP, p53 binding protein 2, p53BP2, PPP1R13A, TP53BP2
• Gene Symbols: TP53BP2
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody