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8-pCPT-2-O-Me-cAMP-AM, Tocris Bioscience™ Available on GSA/VA Contract for Federal Government customers only.

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Quantity:
100μg
This item is not returnable. View return policy
1152197-23-3
C20H21ClN5O8PS
557.899
FZMWUFYPEVDWPA-SILPBKOMSA-N
8-pcpt-2-o-me-camp-am,8-cpt-am,8-4-chlorophenylthio-2'-o-methyladenosine-3',5'-cyclic monophosphate acetoxymethyl ester
90488978
[(4aR,6R,7R,7aR)-6-[6-amino-8-(4-chlorophenyl)sulfanylpurin-9-yl]-7-methoxy-2-oxo-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-2-yl]oxymethyl acetate
CC(=O)OCOP1(=O)OCC2C(O1)C(C(O2)N3C4=C(C(=NC=N4)N)N=C3SC5=CC=C(C=C5)Cl)OC
This item is not returnable. View return policy
1152197-23-3
C20H21ClN5O8PS
557.899
FZMWUFYPEVDWPA-SILPBKOMSA-N
8-pcpt-2-o-me-camp-am,8-cpt-am,8-4-chlorophenylthio-2'-o-methyladenosine-3',5'-cyclic monophosphate acetoxymethyl ester
90488978
[(4aR,6R,7R,7aR)-6-[6-amino-8-(4-chlorophenyl)sulfanylpurin-9-yl]-7-methoxy-2-oxo-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-2-yl]oxymethyl acetate
CC(=O)OCOP1(=O)OCC2C(O1)C(C(O2)N3C4=C(C(=NC=N4)N)N=C3SC5=CC=C(C=C5)Cl)OC

Description

Selective Epac activator; cell-permeable analog of 8CPT-2Me-cAMP (Cat. No. 1645)

Selective Epac activator; cAMP analog. Induces Rap activation and junction tightening in HUVECs; triggers adhesion of Jurkat-Epac1 cells to fibronectin. Stimulates insulin secretion in rat INS-1 cells. More potent, cell-permeable analog of 8CPT-2Me-cAMP (Cat. No. 1645).

This product is a mixture of axial and equatorial isomers. Both isomers give 8CPT-2Me-cAMP after esterase cleavage.

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Quantity 100μg
Formula Weight 557.9
Percent Purity >97%
Chemical Name or Material EPAC Activators

Safety and Handling

Recommended Storage : Store at -80°C