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Tocris Bioscience™ A 803467

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Quantity:
10 mg
50 mg
Description
Selective blocker of NaV1.8 channels (IC50 values are 8, 2450, 6740, 7340 and 7380 nM for hNaV1.8, hNaV1.3, hNaV1.7, hNaV1.5 and hNaV1.2 channels respectively). Shows no significant activity against TRPV1, P2X2/3, CaV2.2 and KCNQ2/3 channels. Antinociceptive; potently attenuates mechanical allodynia in two models of neuropathic pain following i.p. administration.
Specifications
Specifications
Quantity | 10 mg |
Formula Weight | 357.79 |
Purity | >98% |
Molecular Weight (g/mol) | 357.79 |
Chemical Name or Material | A 803467 |
Safety and Handling
Recommended Storage | Store at +4°C |
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