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ACAP2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
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Catalog No. 501729166 Shop All Proteintech Group Inc Products
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50-172-9166 150 μL
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Catalog No. 50-172-9166 Supplier Proteintech Group Inc Supplier No. 140291AP150UL
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Description

Rabbit Polyclonal Antibody

The low density lipoprotein (LDL) receptor system coordinates the metabolism of cholesterol, an essential component of the plasma membrane of all mammalian cells. Study of this system has led to an enhanced understanding of the cellular basis of cholesterol homeostasis. It has also brought into focus an important mechanism of metabolic regulation-the process of receptor-mediated endocytosis. Data suggest that the juxtamembranous region of the cytoplasmic domain participates in protein:protein interactions that allow the low density lipoprotein receptor to cluster in coated pits. It has been shown that the family of LDL receptors may serve as viral receptors. Endocytosis of the Flaviviridae viruses, hepatitis C virus, GB virus C/hepatitis G virus, and bovine viral diarrheal virus (BVDV) was shown to be mediated by LDL receptors on cultured cells.

Specifications

Antigen ACAP2
Applications Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 0.15 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene ACAP2
Gene Accession No. Q15057, Q5FVC7, Q6ZQK5
Gene Alias ACAP2, Centaurin beta 2, CENTB2, CNT B2, KIAA0041
Gene Symbols Acap2
Host Species Rabbit
Immunogen ACAP2 Fusion Protein Ag5190
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23527, 619382, 78618
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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